Curcumin mitigates deoxynivalenol-induced intestinal epithelial barrier disruption by regulating Nrf2/p53 and NF-κB/MLCK signaling in mice

Curcumin Alleviates Dextran Sulfate Sodium‐Induced Colitis in Mice Through Regulating Gut Microbiota

(2022) Xiaoxuan Guo et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Dissecting the Crosstalk Between Nrf2 and NF-κB Response Pathways in Drug-Induced Toxicity

(2022) Wen Gao et al.   Frontiers in Cell and Developmental Biology

Aflatoxin B1 disrupts blood-testis barrier integrity by reducing junction protein and promoting apoptosis in mice testes

(2021) Wanyue Huang et al.   FOOD AND CHEMICAL TOXICOLOGY

Pterostilbene Ameliorates DSS-Induced Intestinal Epithelial Barrier Loss in Mice via Suppression of the NF-κB-Mediated MLCK-MLC Signaling Pathway

(2021) Juan Wang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Protective effects of curcumin against rat intestinal inflammation‑related motility disorders

(2021) Yang Yao et al.   Molecular Medicine Reports

Mechanism of deoxynivalenol mediated gastrointestinal toxicity: Insights from mitochondrial dysfunction

(2021) Shuai Wang et al.   FOOD AND CHEMICAL TOXICOLOGY

Total glucosides of Paeony restores intestinal barrier function through inhibiting Lyn/Snail signaling pathway in colitis mice

(2021) Xin-Yue Cao et al.   PHYTOMEDICINE

Deoxynivalenol and Zearalenone—Synergistic or Antagonistic Agri-Food Chain Co-Contaminants?

(2021) Asmita Thapa et al.   Toxins

Lycopene Protects Intestinal Epithelium from Deoxynivalenol-Induced Oxidative Damage via Regulating Keap1/Nrf2 Signaling

(2021) Shahid Ali Rajput et al.   Antioxidants

Deoxynivalenol photocatalytic detoxification products alleviate intestinal barrier damage and gut flora disorder in BLAB/c mice

(2021) You Zhou et al.   FOOD AND CHEMICAL TOXICOLOGY

Dietary Exposure to the Food Contaminant Deoxynivalenol Triggers Colonic Breakdown by Activating the Mitochondrial and the Death Receptor Pathways

(2021) Delphine Payros et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Deoxynivalenol induced spermatogenesis disorder by blood-testis barrier disruption associated with testosterone deficiency and inflammation in mice

(2020) Zheng Cao et al.   ENVIRONMENTAL POLLUTION

Gly-Pro-Ala peptide and FGSHF3 exert protective effects in DON-induced toxicity and intestinal damage via decreasing oxidative stress

(2020) Zhao Deng et al.   FOOD RESEARCH INTERNATIONAL

The LipoxinA4 receptor agonist BML-111 ameliorates intestinal disruption following acute pancreatitis through the Nrf2-regulated antioxidant pathway

(2020) Zhehao Shi et al.   FREE RADICAL BIOLOGY AND MEDICINE

The impact of chlorophyllin on deoxynivalenol transport across jejunum mucosa explants obtained from adult pigs

(2019) Marta Mendel et al.   Mycotoxin Research

A Protective Role of the NRF2-Keap1 Pathway in Maintaining Intestinal Barrier Function

(2019) Zhiyong Wen et al.   Oxidative Medicine and Cellular Longevity

Deoxynivalenol induced apoptosis and inflammation of IPEC-J2 cells by promoting ROS production

(2019) Ruifen Kang et al.   ENVIRONMENTAL POLLUTION

Curcumin Mitigates Immune-Induced Epithelial Barrier Dysfunction by Campylobacter jejuni

(2019) Fábia Daniela Lobo de Sá et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Curcumin prevents high-fat diet-induced hepatic steatosis in ApoE−/− mice by improving intestinal barrier function and reducing endotoxin and liver TLR4/NF-κB inflammation

(2019) Dan Feng et al.   Nutrition & Metabolism

Apoptosis and Clearance of Apoptotic Cells

(2018) Shigekazu Nagata   Annual Review of Immunology

Combined effects of deoxynivalenol and zearalenone on oxidative injury and apoptosis in porcine splenic lymphocytes in vitro

(2017) Zhihua Ren et al.   EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY

Curcumin Alleviates the Functional Gastrointestinal Disorders of Mice In Vivo

(2017) Jing Yu et al.   JOURNAL OF MEDICINAL FOOD

The intestinal barrier: a fundamental role in health and disease

(2017) Maaike Vancamelbeke et al.   Expert Review of Gastroenterology & Hepatology

Physiology of Intestinal Absorption and Secretion

(2016) Pawel R. Kiela et al.   BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY

Curcumin, the golden nutraceutical: multitargeting for multiple chronic diseases

(2016) Ajaikumar B Kunnumakkara et al.   BRITISH JOURNAL OF PHARMACOLOGY

Nrf2 Knockdown Disrupts the Protective Effect of Curcumin on Alcohol-Induced Hepatocyte Necroptosis

(2016) Chunfeng Lu et al.   MOLECULAR PHARMACEUTICS

The intestinal epithelial barrier: a therapeutic target?

(2016) Matthew A. Odenwald et al.   Nature Reviews Gastroenterology & Hepatology

Deoxynivalenol induces apoptosis in mouse thymic epithelial cells through mitochondria-mediated pathway

(2014) Daotong Li et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Role of oxidative stress in Deoxynivalenol induced toxicity

(2014) Sakshi Mishra et al.   FOOD AND CHEMICAL TOXICOLOGY

Lipopolysaccharide-Induced Expression of NAD(P)H:Quinone Oxidoreductase 1 and Heme Oxygenase-1 Protects against Excessive Inflammatory Responses in Human Monocytes

(2014) S. A. Rushworth et al.   JOURNAL OF IMMUNOLOGY

The Impact of Fusarium Mycotoxins on Human and Animal Host Susceptibility to Infectious Diseases

(2014) Gunther Antonissen et al.   Toxins

Role of Nrf2 in Oxidative Stress and Toxicity

(2013) Qiang Ma   Annual Review of Pharmacology and Toxicology

Myosin light chain kinase: pulling the strings of epithelial tight junction function

(2012) Kevin E. Cunningham et al.   Annals of the New York Academy of Sciences

Glutathione synthesis

(2012) Shelly C. Lu   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Regulation of intestinal epithelial permeability by tight junctions

(2012) Takuya Suzuki   CELLULAR AND MOLECULAR LIFE SCIENCES

Apoptosis, necrosis and necroptosis: cell death regulation in the intestinal epithelium

(2012) Claudia Günther et al.   GUT

Inhibition of NF-κB nuclear translocation via HO-1 activation underlies α-tocopheryl succinate toxicity

(2012) Ilaria Bellezza et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Cyclo(His-Pro) exerts anti-inflammatory effects by modulating NF-κB and Nrf2 signalling

(2011) Alba Minelli et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Small Interfering RNA Targeting Heme Oxygenase-1 (HO-1) Reinforces Liver Apoptosis Induced by Ischemia–Reperfusion Injury in Mice: HO-1 Is Necessary for Cytoprotection

(2009) Bibo Ke et al.   HUMAN GENE THERAPY

NF-κB/p65 antagonizes Nrf2-ARE pathway by depriving CBP from Nrf2 and facilitating recruitment of HDAC3 to MafK

(2008) Guang-Hui Liu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

DNA-PK suppresses a p53-independent apoptotic response to DNA damage

(2008) Kay E Gurley et al.   EMBO REPORTS

Inflammation and Intestinal Function: Where Does It Start and What Does It Mean?

(2008) Kelly A. Tappenden   JOURNAL OF PARENTERAL AND ENTERAL NUTRITION