Knockdown of circHIPK3 promotes the osteogenic differentiation of human bone marrow mesenchymal stem cells through activating the autophagy flux

Exosomal hsa_circ_0006859 is a potential biomarker for postmenopausal osteoporosis and enhances adipogenic versus osteogenic differentiation in human bone marrow mesenchymal stem cells by sponging miR-431-5p

(2021) Feng Zhi et al.   Stem Cell Research & Therapy

circHIPK3 regulates proliferation and differentiation of myoblast through the miR‐7/ TCF12 pathway

(2021) Mengjin Gao et al.   JOURNAL OF CELLULAR PHYSIOLOGY

CircHIPK3 regulates the autophagy and apoptosis of hypoxia/reoxygenation-stimulated cardiomyocytes via the miR-20b-5p/ATG7 axis

(2021) Zhimei Qiu et al.   Cell Death Discovery

Mesenchymal stem cell-derived extracellular vesicles prevent the development of osteoarthritis via the circHIPK3/miR-124-3p/MYH9 axis

(2021) Shenglong Li et al.   JOURNAL OF NANOBIOTECHNOLOGY

Autophagy, Mesenchymal Stem Cell Differentiation, and Secretion

(2021) Mikhail Menshikov et al.   Biomedicines

Extracellular IL-37 promotes osteogenic and odontogenic differentiation of human dental pulp stem cells via autophagy

(2021) Na Li et al.   EXPERIMENTAL CELL RESEARCH

Circular RNA CircHIPK3 Promotes Homeostasis of the Intestinal Epithelium by Reducing MicroRNA 29b Function

(2021) Lan Xiao et al.   GASTROENTEROLOGY

Insulin impedes osteogenesis of BMSCs by inhibiting autophagy and promoting premature senescence via the TGF-β1 pathway

(2020) Ping Zhang et al.   Aging-US

Melatonin attenuates vascular calcification by activating autophagy via an AMPK/mTOR/ULK1 signaling pathway

(2020) Wei Ren Chen et al.   EXPERIMENTAL CELL RESEARCH

Validation of a long bone fracture non-union healing score after treatment with mesenchymal stromal cells combined to biomaterials

(2020) Enrique Gómez-Barrena et al.   INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED

The functional interplay of lncRNA EGOT and HuR regulates hypoxia‐induced autophagy in renal tubular cells

(2020) I‐Kuan Wang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

The circular RNA HIPK3 (circHIPK3) and its regulation in cancer progression: Review

(2020) Yimin Xie et al.   LIFE SCIENCES

Interaction between HuR and circPABPN1 Modulates Autophagy in the Intestinal Epithelium by Altering ATG16L1 Translation

(2020) Xiao-Xue Li et al.   MOLECULAR AND CELLULAR BIOLOGY

The roles of autophagy in osteogenic differentiation in rat ligamentum fibroblasts: Evidence and possible implications

(2020) Yuehua Yang et al.   FASEB JOURNAL

Long non-coding RNA MIR22HG promotes osteogenic differentiation of bone marrow mesenchymal stem cells via PTEN/ AKT pathway

(2020) Chanyuan Jin et al.   Cell Death & Disease

Irisin promotes osteogenic differentiation of bone marrow mesenchymal stem cells by activating autophagy via the Wnt//β-catenin signal pathway

(2020) Xi Chen et al.   CYTOKINE

AMP-activated protein kinase and the down-stream activated process of autophagy regulate the osteogenic differentiation of human dental follicle cells

(2020) Oliver Pieles et al.   ARCHIVES OF ORAL BIOLOGY

circDCUN1D4 suppresses tumor metastasis and glycolysis in lung adenocarcinoma by stabilizing TXNIP expression

(2020) Yingkuan Liang et al.   Molecular Therapy-Nucleic Acids

Circular RNA circHIPK3 Promotes the Proliferation and Differentiation of Chicken Myoblast Cells by Sponging miR-30a-3p

(2019) Biao Chen et al.   Cells

Translation of a standardized manufacturing protocol for mesenchymal stromal cells: A systematic comparison of validation and manufacturing data

(2019) MARKUS THOMAS ROJEWSKI et al.   CYTOTHERAPY

Crosstalk between autophagy and epithelial-mesenchymal transition and its application in cancer therapy

(2019) Hong-Tao Chen et al.   Molecular Cancer

Circular RNA circHIPK3 modulates autophagy via MIR124-3p-STAT3-PRKAA/AMPKα signaling in STK11 mutant lung cancer

(2019) Xiuyuan Chen et al.   Autophagy

Autophagy drives osteogenic differentiation of human gingival mesenchymal stem cells

(2019) Chiara Vidoni et al.   Cell Communication and Signaling

Involvement of HuR in the serum starvation induced autophagy through regulation of Beclin1 in breast cancer cell-line, MCF-7

(2019) Soumasree De et al.   CELLULAR SIGNALLING

Mitochondrial phosphoenolpyruvate carboxykinase (PCK2) regulates osteogenic differentiation by modulating AMPK/ULK1-dependent autophagy

(2019) Zheng Li et al.   STEM CELLS

Circ-HIPK3 plays an active role in regulating myoblast differentiation

(2019) Rui Yao et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

LncRNA-HGBC stabilized by HuR promotes gallbladder cancer progression by regulating miR-502-3p/SET/AKT axis

(2019) Yun-ping Hu et al.   Molecular Cancer

circHIPK3 promotes oxaliplatin-resistance in colorectal cancer through autophagy by sponging miR-637

(2019) Yanli Zhang et al.   EBioMedicine

Toll-like receptor 4 knockout protects against diabetic-induced imbalance of bone metabolism via autophagic suppression

(2019) Yongze Zhang et al.   MOLECULAR IMMUNOLOGY

Functional reconstruction of critical-sized load-bearing bone defects using a Sclerostin-targeting miR-210-3p-based construct to enhance osteogenic activity

(2018) Bin Hu et al.   Acta Biomaterialia

CircHIPK3 promotes colorectal cancer growth and metastasis by sponging miR-7

(2018) Kaixuan Zeng et al.   Cell Death & Disease

A Multicentric, Open-Label, Randomized, Comparative Clinical Trial of Two Different Doses of Expanded hBM-MSCs Plus Biomaterial versus Iliac Crest Autograft, for Bone Healing in Nonunions after Long Bone Fractures: Study Protocol

(2018) Enrique Gómez-Barrena et al.   Stem Cells International

Circular RNA CDR1as regulates osteoblastic differentiation of periodontal ligament stem cells via the miR-7/GDF5/SMAD and p38 MAPK signaling pathway

(2018) Xiaobei Li et al.   Stem Cell Research & Therapy

Circular RNA circAGO2 drives cancer progression through facilitating HuR-repressed functions of AGO2-miRNA complexes

(2018) Yajun Chen et al.   CELL DEATH AND DIFFERENTIATION

RNA-binding protein, human antigen R regulates hypoxia-induced autophagy by targeting ATG7/ATG16L1 expressions and autophagosome formation

(2018) Kalaiselvi Palanisamy et al.   JOURNAL OF CELLULAR PHYSIOLOGY

A peptide encoded by circular form of LINC-PINT suppresses oncogenic transcriptional elongation in glioblastoma

(2018) Maolei Zhang et al.   Nature Communications

The Circular RNA Landscape of Periodontal Ligament Stem Cells During Osteogenesis

(2017) Yunfei Zheng et al.   JOURNAL OF PERIODONTOLOGY

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

(2016) Daniel J Klionsky et al.   Autophagy

Healing of osteoporotic bone defects by baculovirus-engineered bone marrow-derived MSCs expressing MicroRNA sponges

(2016) Kuei-Chang Li et al.   BIOMATERIALS

Foxo3 circular RNA retards cell cycle progression via forming ternary complexes with p21 and CDK2

(2016) William W. Du et al.   NUCLEIC ACIDS RESEARCH

Inhibition of lncRNA MIR31HG Promotes Osteogenic Differentiation of Human Adipose-Derived Stem Cells

(2016) Chanyuan Jin et al.   STEM CELLS

Circular RNA profiling reveals an abundant circHIPK3 that regulates cell growth by sponging multiple miRNAs

(2016) Qiupeng Zheng et al.   Nature Communications

Posttranslational control of HuR function

(2016) Ioannis Grammatikakis et al.   Wiley Interdisciplinary Reviews-RNA

CircInteractome: A web tool for exploring circular RNAs and their interacting proteins and microRNAs

(2015) Dawood B. Dudekula et al.   RNA Biology

circRNA Biogenesis Competes with Pre-mRNA Splicing

(2014) Reut Ashwal-Fluss et al.   MOLECULAR CELL

Circular RNAs are a large class of animal RNAs with regulatory potency

(2013) Sebastian Memczak et al.   NATURE

Predicting RNA-Protein Interactions Using Only Sequence Information

(2011) Usha K Muppirala et al.   BMC BIOINFORMATICS

Autophagy: Renovation of Cells and Tissues

(2011) Noboru Mizushima et al.   CELL