LncRNA Airn maintains LSEC differentiation to alleviate liver fibrosis via the KLF2-eNOS-sGC pathway

Glycolysis-associated lncRNAs identify a subgroup of cancer patients with poor prognoses and a high-infiltration immune microenvironment

(2021) Kuo-Hao Ho et al.   BMC Medicine

Angiodiversity and organotypic functions of sinusoidal endothelial cells

(2021) Philipp-Sebastian Koch et al.   ANGIOGENESIS

HBeAg mediates inflammatory functions of macrophages by TLR2 contributing to hepatic fibrosis

(2021) Xiaoyu Xie et al.   BMC Medicine

OTULIN protects the liver against cell death, inflammation, fibrosis, and cancer

(2020) Rune Busk Damgaard et al.   CELL DEATH AND DIFFERENTIATION

Transcriptional factor ATF3 promotes liver fibrosis via activating hepatic stellate cells

(2020) Zhemin Shi et al.   Cell Death & Disease

KLF2 regulates eNOS uncoupling via Nrf2/HO-1 in endothelial cells under hypoxia and reoxygenation

(2019) WeiDang Wu et al.   CHEMICO-BIOLOGICAL INTERACTIONS

lncRNA Spehd Regulates Hematopoietic Stem and Progenitor Cells and Is Required for Multilineage Differentiation

(2019) M. Joaquina Delás et al.   Cell Reports

AirnRegulates Igf2bp2 Translation in CardiomyocytesNovelty and Significance

(2018) Mohammed Rabiul Hosen et al.   CIRCULATION RESEARCH

Inhibition of hsa-miR-6086 protects human umbilical vein endothelial cells against TNFα-induced proliferation inhibition and apoptosis via CDH5

(2018) Xueli Cai et al.   GENE

Endothelial Notch activation reshapes the angiocrine of sinusoidal endothelia to aggravate liver fibrosis and blunt regeneration in mice

(2018) Juan-Li Duan et al.   HEPATOLOGY

Incomplete differentiation of engrafted bone marrow endothelial progenitor cells initiates hepatic fibrosis in the rat

(2018) Ana C. Maretti-Mira et al.   HEPATOLOGY

Targeting Endothelial Erk1/2-Akt Axis as a Regeneration Strategy to Bypass Fibrosis during Chronic Liver Injury in Mice

(2018) Yuanxiang Lao et al.   MOLECULAR THERAPY

LncRNA GHET1 predicts poor prognosis in hepatocellular carcinoma and promotes cell proliferation by silencing KLF2

(2017) Li Jin et al.   JOURNAL OF CELLULAR PHYSIOLOGY

GATA4-dependent organ-specific endothelial differentiation controls liver development and embryonic hematopoiesis

(2017) Cyrill Géraud et al.   JOURNAL OF CLINICAL INVESTIGATION

Liver sinusoidal endothelial cells: Physiology and role in liver diseases

(2017) Johanne Poisson et al.   JOURNAL OF HEPATOLOGY

Long Noncoding RNA LINC00673 Is Activated by SP1 and Exerts Oncogenic Properties by Interacting with LSD1 and EZH2 in Gastric Cancer

(2017) Mingde Huang et al.   MOLECULAR THERAPY

Mechanotransduction-modulated fibrotic microniches reveal the contribution of angiogenesis in liver fibrosis

(2017) Longwei Liu et al.   NATURE MATERIALS

The liver-enriched lnc-LFAR1 promotes liver fibrosis by activating TGFβ and Notch pathways

(2017) Kun Zhang et al.   Nature Communications

Sinusoidal communication in liver fibrosis and regeneration

(2016) Giusi Marrone et al.   JOURNAL OF HEPATOLOGY

Novel matrine derivative MD-1 attenuates hepatic fibrosis by inhibiting EGFR activation of hepatic stellate cells

(2016) Yi Feng et al.   Protein & Cell

Targeting EZH2 and PRC2 dependence as novel anticancer therapy

(2015) Bowen Xu et al.   EXPERIMENTAL HEMATOLOGY

Liver sinusoidal endothelial cells in hepatic fibrosis

(2015) Laurie D. DeLeve   HEPATOLOGY

Exosome Adherence and Internalization by Hepatic Stellate Cells Triggers Sphingosine 1-Phosphate-dependent Migration

(2015) Ruisi Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

KLF2 exerts antifibrotic and vasoprotective effects in cirrhotic rat livers: behind the molecular mechanisms of statins

(2014) Giusi Marrone et al.   GUT

RNA in unexpected places: long non-coding RNA functions in diverse cellular contexts

(2013) Sarah Geisler et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A mammalian pseudogene lncRNA at the interface of inflammation and anti-inflammatory therapeutics

(2013) Nicole A Rapicavoli et al.   eLife

Hedgehog signalling regulates liver sinusoidal endothelial cell capillarisation

(2012) Guanhua Xie et al.   GUT

The transcription factor KLF2 mediates hepatic endothelial protection and paracrine endothelial–stellate cell deactivation induced by statins

(2012) Giusi Marrone et al.   JOURNAL OF HEPATOLOGY

Role of Differentiation of Liver Sinusoidal Endothelial Cells in Progression and Regression of Hepatic Fibrosis in Rats

(2011) Guanhua Xie et al.   GASTROENTEROLOGY

Intestinal decontamination inhibits TLR4 dependent fibronectin-mediated cross-talk between stellate cells and endothelial cells in liver fibrosis in mice

(2011) Qiang Zhu et al.   JOURNAL OF HEPATOLOGY

Endothelial expression of transcription factor Kruppel-like factor 2 and its vasoprotective target genes in the normal and cirrhotic rat liver

(2010) J. Gracia-Sancho et al.   GUT

Liver sinusoidal endothelium: A microenvironment-dependent differentiation program in rat including the novel junctional protein liver endothelial differentiation-associated protein-1

(2010) Cyrill Géraud et al.   HEPATOLOGY

Inductive angiocrine signals from sinusoidal endothelium are required for liver regeneration

(2010) Bi-Sen Ding et al.   NATURE

Hepatic Stellate Cells Secrete Angiopoietin 1 That Induces Angiogenesis in Liver Fibrosis

(2008) Kojiro Taura et al.   GASTROENTEROLOGY

Sinusoidal endothelial cells prevent rat stellate cell activation and promote reversion to quiescence

(2008) Laurie D. DeLeve et al.   HEPATOLOGY

Murine CD146 is widely expressed on endothelial cells and is recognized by the monoclonal antibody ME-9F1

(2008) Arnhild Schrage et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Hepatic Stellate Cells: Protean, Multifunctional, and Enigmatic Cells of the Liver

(2008) Scott L. Friedman   PHYSIOLOGICAL REVIEWS

Hepatic fibrosis—Overview

(2008) Scott L. Friedman   TOXICOLOGY