Synthesis of Axially Chiral Biaryls via Enantioselective Ullmann Coupling of ortho ‐Chlorinated Aryl Aldehydes Enabled by a Chiral 2,2′‐Bipyridine Ligand

Catalytic Asymmetric Synthesis of Axially Chiral 3,3'‐Bisindoles by Direct Coupling of Indole Rings

(2022) Feng‐Tao Sheng et al.   CHINESE JOURNAL OF CHEMISTRY

Enantioselective Au(I)/Au(III) Redox Catalysis Enabled by Chiral (P,N)-Ligands

(2022) Chetan C. Chintawar et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Asymmetric Construction of Axially and Centrally Chiral Heterobiaryls by Minisci Reaction

(2022) Dong Liang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Atropisomeric Phosphine Ligands Bearing C–N Axial Chirality: Applications in Enantioselective Suzuki–Miyaura Cross-Coupling Towards the Assembly of Tetra-ortho-Substituted Biaryls

(2022) Kin Boon Gan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Pd-Catalyzed Atroposelective C–H Acyloxylation Enabling Access to an Axially Chiral Biaryl Phenol Organocatalyst

(2022) Jitan Zhang et al.   ORGANIC LETTERS

Construction of axial chirality via asymmetric radical trapping by cobalt under visible light

(2022) Xuan Jiang et al.   Nature Catalysis

Synthesis of Axially Chiral 2,2′-Bisphosphobiarenes via a Nickel-Catalyzed Asymmetric Ullmann Coupling: General Access to Privileged Chiral Ligands without Optical Resolution

(2021) Ziqing Zuo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chiral Phosphoric Acid Catalyzed Asymmetric Synthesis of Axially Chiral Compounds

(2021) Bing‐Chao Da et al.   CHINESE JOURNAL OF CHEMISTRY

Enantioselective Synthesis of Axially Chiral Biaryls by Diels–Alder/Retro-Diels–Alder Reaction of 2-Pyrones with Alkynes

(2021) Meng-Meng Xu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Development of a Tunable Chiral Pyridine Ligand Unit for Enantioselective Iridium-Catalyzed C–H Borylation

(2021) Peidong Song et al.   ACS Catalysis

Asymmetric C–H Activation for the Synthesis of P- and Axially Chiral Biaryl Phosphine Oxides by an Achiral Cp*Ir Catalyst with Chiral Carboxylic Amide

(2021) Chao-Wei Zhang et al.   ACS Catalysis

Catalytic Atroposelective Catellani Reaction Enables Construction of Axially Chiral Biaryl Monophosphine Oxides

(2021) Qiang Feng et al.   CCS Chemistry

Stereochemistry and Recent Applications of Axially Chiral Organic Molecules.

(2020) Michele Mancinelli et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Axially Chiral Biaryl Monophosphine Oxides Enabled by Palladium/WJ-Phos-Catalyzed Asymmetric Suzuki–Miyaura Cross-coupling

(2020) Wangqin Ji et al.   ACS Catalysis

Enantioselective Cross-Coupling for Axially Chiral Tetra-ortho-Substituted Biaryls and Asymmetric Synthesis of Gossypol

(2020) He Yang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Ni-Catalyzed Electrochemical Synthesis of Biaryl Atropisomers

(2020) Hui Qiu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Atroposelective Synthesis of Axially Chiral N‐Arylpyrroles by Chiral‐at‐Rhodium Catalysis

(2020) Chen‐Xi Ye et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nickel-Catalyzed Asymmetric Cross-Electrophile Coupling Reactions

(2020) Chuan Wang et al.   SYNLETT

Nickel-Catalyzed Enantioselective Reductive Cross-Coupling Reactions

(2020) Kelsey E. Poremba et al.   ACS Catalysis

Construction of axial chirality via palladium/chiral norbornene cooperative catalysis

(2020) Ze-Shui Liu et al.   Nature Catalysis

Combining Chiral Aldehyde Catalysis and Transition-Metal Catalysis for Enantioselective α-Allylic Alkylation of Amino Acid Esters

(2019) Lei Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Synthesis of Biaryl Atropisomers via Pd-Catalyzed C-H Olefination using Chiral Spiro Phosphoric Acid Ligands

(2019) Jun Luo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Design of Phosphinic Acid Catalysts with the Closest Stereogenicity at the α-Position: Synthesis and Application of α-Stereogenic Perfluoroalkyl Phosphinic Acid Catalysts

(2019) Kohei Fujii et al.   ORGANIC LETTERS

Enantioselective Synthesis of Axially Chiral Biaryls via Cu-Catalyzed Acyloxylation of Cyclic Diaryliodonium Salts

(2019) Kai Zhu et al.   ACS Catalysis

Synthesis of Chiral Aldehyde Catalysts by Pd-Catalyzed Atroposelective C−H Naphthylation

(2019) Gang Liao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Z‐bpy, a New C 2 ‐Symmetric Bipyridine Ligand and Its Application in Enantioselective Copper(I)‐Catalyzed Cyclopropanation of Olefins

(2019) Yizhao Ouyang et al.   CHINESE JOURNAL OF CHEMISTRY

LiCl-Accelerated Multimetallic Cross-Coupling of Aryl Chlorides with Aryl Triflates

(2019) Liangbin Huang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rhodium-Catalyzed Atroposelective C–H Arylation: Efficient Synthesis of Axially Chiral Heterobiaryls

(2019) Qiang Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

NHC-catalyzed atropoenantioselective synthesis of axially chiral biaryl amino alcohols via a cooperative strategy

(2019) Gongming Yang et al.   Nature Communications

A Bulky Chiral N-Heterocyclic Carbene Palladium Catalyst Enables Highly Enantioselective Suzuki–Miyaura Cross-Coupling Reactions for the Synthesis of Biaryl Atropisomers

(2019) Di Shen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Atroposelective synthesis of tetra-ortho-substituted biaryls by catalyst-controlled non-canonical polyketide cyclizations

(2019) Reto M. Witzig et al.   Nature Catalysis

Chiral-Organotin-Catalyzed Kinetic Resolution of Vicinal Amino Alcohols

(2019) Hui Yang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Strategy for Synthesizing Axially Chiral Naphthyl-Indoles: Catalytic Asymmetric Addition Reactions of Racemic Substrates

(2019) Fei Jiang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Construction of Axially Chiral Compounds via Asymmetric Organocatalysis

(2018) Yong-Bin Wang et al.   ACCOUNTS OF CHEMICAL RESEARCH

Chiral Aldehyde Catalysis for the Catalytic Asymmetric Activation of Glycine Esters

(2018) Wei Wen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Direct Dehydrogenative Arylation of Benzaldehydes with Arenes Using Transient Directing Groups

(2018) Da-Yu Wang et al.   ORGANIC LETTERS

Carbonyl catalysis enables a biomimetic asymmetric Mannich reaction

(2018) Jianfeng Chen et al.   SCIENCE

Catalyst-Controlled Stereoselective Synthesis of Atropisomers

(2018) Bouthayna Zilate et al.   ACS Catalysis

Enantioselective Synthesis of Biaryl Atropisomers via Pd/Norbornene-Catalyzed Three-Component Cross-Couplings

(2018) Linlin Ding et al.   ACS Catalysis

Enantioselective Carbonyl Catalysis Enabled by Chiral Aldehydes

(2018) Shuli You et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ni-Catalyzed Reductive Coupling of Electron-Rich Aryl Iodides with Tertiary Alkyl Halides

(2018) Xuan Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Recent advances in gossypol derivatives and analogs: a chemistry and biology view

(2017) Yuzhi Lu et al.   Future Medicinal Chemistry

Brønsted acid-catalysed enantioselective construction of axially chiral arylquinazolinones

(2017) Yong-Bin Wang et al.   Nature Communications

Enantioselective Synthesis of Indole-Based Biaryl Atropisomers via Palladium-Catalyzed Dynamic Kinetic Intramolecular C–H Cyclization

(2017) Congfa He et al.   ACS Catalysis

Synthesis of axially chiral biaryl compounds by asymmetric catalytic reactions with transition metals

(2016) Pauline Loxq et al.   COORDINATION CHEMISTRY REVIEWS

N,B-Bidentate Boryl Ligand-Supported Iridium Catalyst for Efficient Functional-Group-Directed C–H Borylation

(2016) Guanghui Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nickel-Catalyzed Reductive Couplings

(2016) Xuan Wang et al.   Topics in Current Chemistry

Methods and Mechanisms for Cross-Electrophile Coupling of Csp2 Halides with Alkyl Electrophiles

(2015) Daniel J. Weix   ACCOUNTS OF CHEMICAL RESEARCH

Nonbiaryl and Heterobiaryl Atropisomers: Molecular Templates with Promise for Atropselective Chemical Transformations

(2015) Elango Kumarasamy et al.   CHEMICAL REVIEWS

Enantioselective and Enantiospecific Transition-Metal-Catalyzed Cross-Coupling Reactions of Organometallic Reagents To Construct C–C Bonds

(2015) Alan H. Cherney et al.   CHEMICAL REVIEWS

Recent advances and new concepts for the synthesis of axially stereoenriched biaryls

(2015) J. Wencel-Delord et al.   CHEMICAL SOCIETY REVIEWS

Double N,B-Type Bidentate Boryl Ligands Enabling a Highly Active Iridium Catalyst for C–H Borylation

(2015) Guanghui Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A twist of nature – the significance of atropisomers in biological systems

(2015) Jamie E. Smyth et al.   NATURAL PRODUCT REPORTS

Multimetallic catalysed cross-coupling of aryl bromides with aryl triflates

(2015) Laura K. G. Ackerman et al.   NATURE

Design and synthesis of the first triply twisted Möbius annulene

(2014) Gaston R. Schaller et al.   Nature Chemistry

Chemoselective Tin–Boron Exchange Aided by the Use of Dummy Ligands at the Tin Atom

(2014) Julia Hermeke et al.   ORGANOMETALLICS

Catalytic asymmetric direct α-alkylation of amino esters by aldehydes via imine activation

(2014) Biao Xu et al.   Chemical Science

Synthesis of binaphthyl based phosphine and phosphite ligands

(2013) Mariette M. Pereira et al.   CHEMICAL SOCIETY REVIEWS

Efficient Syntheses of Korupensamines A, B and Michellamine B by Asymmetric Suzuki-Miyaura Coupling Reactions

(2013) Guangqing Xu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric Bromine–Lithium Exchange: Application toward the Synthesis of Natural Product

(2013) Julien Graff et al.   ORGANIC LETTERS

Therapeutic potential of gossypol: An overview

(2013) Hoda Keshmiri-Neghab et al.   PHARMACEUTICAL BIOLOGY

Ring-Expansion Reactions of Binaphthyl Azepines and Ferrocenophanes through Metal-Catalyzed [1,2]-Stevens Rearrangements

(2013) Jérôme Lacour et al.   SYNTHESIS-STUTTGART

Atroposelective Total Synthesis of Axially Chiral Biaryl Natural Products

(2010) Gerhard Bringmann et al.   CHEMICAL REVIEWS

Nickel-Catalyzed Cross-Couplings Involving Carbon−Oxygen Bonds

(2010) Brad M. Rosen et al.   CHEMICAL REVIEWS

Enantioselective Synthesis of Axially Chiral Biaryls by the Pd-Catalyzed Suzuki−Miyaura Reaction: Substrate Scope and Quantum Mechanical Investigations

(2010) Xiaoqiang Shen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Development of Binaphthyl-Based Chiral Dienes for Rhodium(I)-Catalyzed Asymmetric Arylation ofN,N-Dimethylsulfamoyl-Protected Aldimines

(2010) Ziping Cao et al.   ORGANIC LETTERS

Nickel-Catalyzed Asymmetric Ullmann Coupling for the Synthesis of Axially Chiral Tetra-ortho-Substituted Biaryl Dials

(2010) Wen-Wen Chen et al.   ORGANIC LETTERS

Chiral Diene as the Ligand for the Synthesis of Axially Chiral Compounds via Palladium-Catalyzed Suzuki−Miyaura Coupling Reaction

(2010) Shu-Sheng Zhang et al.   ORGANIC LETTERS

The Challenge of Atropisomerism in Drug Discovery

(2009) Jonathan Clayden et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Total synthesis of chiral biaryl natural products by asymmetric biaryl coupling

(2009) Marisa C. Kozlowski et al.   CHEMICAL SOCIETY REVIEWS

An Open-Label, Multicenter, Phase I/II Study of Single-Agent AT-101 in Men with Castrate-Resistant Prostate Cancer

(2009) G. Liu et al.   CLINICAL CANCER RESEARCH

An Efficient and Versatile Approach for Optical Resolution ofC2-Symmetric Axially Chiral Biaryl Dials. Synthesis of Enantiopure Biaryl-Derived Cyclictrans-1,2-Diols

(2008) Chen Zhu et al.   ORGANIC LETTERS

Combinatorial approach for the design of new, simplified chiral phase-transfer catalysts with high catalytic performance for practical asymmetric synthesis of α-alkyl-α-amino acids

(2008) Masanori Kitamura et al.   TETRAHEDRON LETTERS