CD6 modulates thymocyte selection and peripheral T cell homeostasis

The Link Between CD6 and Autoimmunity: Genetic and Cellular Associations

(2016) David M. Kofler et al.   CURRENT DRUG TARGETS

Therapeutic Targeting of CD6 in Autoimmune Diseases: A Review of Cuban Clinical Studies with the Antibodies IOR-T1 and Itolizumab

(2016) Patricia Hernández et al.   CURRENT DRUG TARGETS

Tuning T Cell Activation: The Function of CD6 At the Immunological Synapse and in T Cell Responses

(2016) Rita F. Santos et al.   CURRENT DRUG TARGETS

Regulatory T Cells Require TCR Signaling for Their Suppressive Function

(2015) Amanda M. Schmidt et al.   JOURNAL OF IMMUNOLOGY

Structures of CD6 and Its Ligand CD166 Give Insight into Their Interaction

(2015) Paul E. Chappell et al.   STRUCTURE

Modulation of CD6 function through interaction with Galectin-1 and -3

(2014) Cristina Escoda-Ferran et al.   FEBS LETTERS

Quantitative proteomics analysis of signalosome dynamics in primary T cells identifies the surface receptor CD6 as a Lat adaptor–independent TCR signaling hub

(2014) Romain Roncagalli et al.   NATURE IMMUNOLOGY

The TCR's sensitivity to self peptide–MHC dictates the ability of naive CD8+ T cells to respond to foreign antigens

(2014) Ross B Fulton et al.   NATURE IMMUNOLOGY

Identification of functionally relevant phoshorylatable serine clusters in the cytoplasmic region of the human CD6 lymphocyte surface receptor

(2013) Lizette Bonet et al.   FEBS LETTERS

ORMDL3 modulates store-operated calcium entry and lymphocyte activation

(2012) Amado Carreras-Sureda et al.   HUMAN MOLECULAR GENETICS

Exacerbation of type II collagen-induced arthritis in apolipoprotein E-deficient mice in association with the expansion of Th1 and Th17 cells

(2011) Jorge Postigo et al.   ARTHRITIS AND RHEUMATISM

The immunomodulatory properties of the CD5 lymphocyte receptor in health and disease

(2011) Gloria Soldevila et al.   CURRENT OPINION IN IMMUNOLOGY

CD6 attenuates early and late signaling events, setting thresholds for T-cell activation

(2011) Marta I. Oliveira et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

A conditional knockout resource for the genome-wide study of mouse gene function

(2011) William C. Skarnes et al.   NATURE

Increased numbers of thymic and peripheral CD4+ CD25+Foxp3+ cells in the absence of CD5 signaling

(2009) Diana Ordoñez-Rueda et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Low Ligand Requirement for Deletion and Lack of Synapses in Positive Selection Enforce the Gauntlet of Thymic T Cell Maturation

(2008) Peter J.R. Ebert et al.   IMMUNITY

CD5 plays an inhibitory role in the suppressive function of murine CD4+ CD25+ Treg cells

(2008) Trivikram Dasu et al.   IMMUNOLOGY LETTERS