Quantitative proteomics analysis of signalosome dynamics in primary T cells identifies the surface receptor CD6 as a Lat adaptor–independent TCR signaling hub

Murine natural killer immunoreceptors use distinct proximal signaling complexes to direct cell function

(2013) R. M. May et al.   BLOOD

Temporal regulation of EGF signalling networks by the scaffold protein Shc1

(2013) Yong Zheng et al.   NATURE

Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS

(2013) Markku Varjosalo et al.   NATURE METHODS

Convergent and divergent effects of costimulatory molecules in conventional and regulatory CD4+ T cells

(2013) E. Wakamatsu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phosphorylation of CDK9 at Ser175 Enhances HIV Transcription and Is a Marker of Activated P-TEFb in CD4+ T Lymphocytes

(2013) Uri R. Mbonye et al.   PLoS Pathogens

Role of LAT in the Granule-Mediated Cytotoxicity of CD8 T Cells

(2012) C.-w. Ou-Yang et al.   MOLECULAR AND CELLULAR BIOLOGY

STING and the innate immune response to nucleic acids in the cytosol

(2012) Dara L Burdette et al.   NATURE IMMUNOLOGY

The integrin LFA-1 signals through ZAP-70 to regulate expression of high-affinity LFA-1 on T lymphocytes

(2011) R. Evans et al.   BLOOD

CD6 attenuates early and late signaling events, setting thresholds for T-cell activation

(2011) Marta I. Oliveira et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Release of serine/threonine-phosphorylated adaptors from signaling microclusters down-regulates T cell activation

(2011) Rémi Lasserre et al.   JOURNAL OF CELL BIOLOGY

The CD6 Multiple Sclerosis Susceptibility Allele Is Associated with Alterations in CD4+ T Cell Proliferation

(2011) D. M. Kofler et al.   JOURNAL OF IMMUNOLOGY

Abacus: A computational tool for extracting and pre-processing spectral count data for label-free quantitative proteomic analysis

(2011) Damian Fermin et al.   PROTEOMICS

Direct Transfer of α-Synuclein from Neuron to Astroglia Causes Inflammatory Responses in Synucleinopathies

(2010) He-Jin Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Role of the LAT–PLC-γ1 Interaction in T Regulatory Cell Function

(2010) Mariana I. Chuck et al.   JOURNAL OF IMMUNOLOGY

A guided tour of the Trans-Proteomic Pipeline

(2010) Eric W. Deutsch et al.   PROTEOMICS

LAT signaling pathology: an “autoimmune” condition without T cell self-reactivity

(2010) Romain Roncagalli et al.   TRENDS IN IMMUNOLOGY

The LAT Story: A Tale of Cooperativity, Coordination, and Choreography

(2010) L. Balagopalan et al.   Cold Spring Harbor Perspectives in Biology

Identifying differences in protein expression levels by spectral counting and feature selection

(2009) P.C. Carvalho et al.   GENETICS AND MOLECULAR RESEARCH

Loss of the LAT Adaptor Converts Antigen-Responsive T Cells into Pathogenic Effectors that Function Independently of the T Cell Receptor

(2009) Michael Mingueneau et al.   IMMUNITY

An integrated workflow for charting the human interaction proteome: insights into the PP2A system

(2009) Timo Glatter et al.   Molecular Systems Biology

Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci

(2009) Philip L De Jager et al.   NATURE GENETICS

Agouti C57BL/6N embryonic stem cells for mouse genetic resources

(2009) Stephen J Pettitt et al.   NATURE METHODS

Quantitative Phosphoproteomic Analysis of T Cell Receptor Signaling Reveals System-Wide Modulation of Protein-Protein Interactions

(2009) V. Mayya et al.   Science Signaling

The proline-rich sequence of CD3ε controls T cell antigen receptor expression on and signaling potency in preselection CD4+CD8+ thymocytes

(2008) Michaël Mingueneau et al.   NATURE IMMUNOLOGY