Regulatory T Cells Require TCR Signaling for Their Suppressive Function

Continuous T Cell Receptor Signals Maintain a Functional Regulatory T Cell Pool

(2014) J. Christoph Vahl et al.   IMMUNITY

Cytotoxic-T-Lymphocyte Antigen 4 Receptor Signaling for Lymphocyte Adhesion Is Mediated by C3G and Rap1

(2014) Y. Kloog et al.   MOLECULAR AND CELLULAR BIOLOGY

Continuous requirement for the TCR in regulatory T cell function

(2014) Andrew G Levine et al.   NATURE IMMUNOLOGY

The adaptor protein Crk in immune response

(2013) Dongfang Liu   IMMUNOLOGY AND CELL BIOLOGY

Thymus-derived regulatory T cells contribute to tolerance to commensal microbiota

(2013) Anna Cebula et al.   NATURE

Diacylglycerol Kinase   Limits the Generation of Natural Regulatory T Cells

(2013) A. M. Schmidt et al.   Science Signaling

Conditional deletion of SLP-76 in mature T cells abrogates peripheral immune responses

(2011) Gregory F. Wu et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Foxp3+ regulatory T cells, immune stimulation and host defence against infection

(2011) Jared H. Rowe et al.   IMMUNOLOGY

T cell receptor signal strength in Tregand iNKT cell development demonstrated by a novel fluorescent reporter mouse

(2011) Amy E. Moran et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Trans-Endocytosis of CD80 and CD86: A Molecular Basis for the Cell-Extrinsic Function of CTLA-4

(2011) O. S. Qureshi et al.   SCIENCE

Cell-autonomous and -non-autonomous roles of CTLA-4 in immune regulation

(2011) Kajsa Wing et al.   TRENDS IN IMMUNOLOGY

Loss of tonic T-cell receptor signals alters the generation but not the persistence of CD8+ memory T cells

(2010) K. R. Wiehagen et al.   BLOOD

Phospholipase Cγ1 is essential for T cell development, activation, and tolerance

(2010) Guoping Fu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A genetically selective inhibitor demonstrates a function for the kinase Zap70 in regulatory T cells independent of its catalytic activity

(2010) Byron B Au-Yeung et al.   NATURE IMMUNOLOGY

ZAP-70: An Essential Kinase in T-cell Signaling

(2010) H. Wang et al.   Cold Spring Harbor Perspectives in Biology

T Cell Activation

(2009) Jennifer E. Smith-Garvin et al.   Annual Review of Immunology

A hypomorphic allele of ZAP-70 reveals a distinct thymic threshold for autoimmune disease versus autoimmune reactivity

(2009) Lih-Yun Hsu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cutting Edge: Regulatory T Cells Do Not Require Stimulation through Their TCR to Suppress

(2009) A. L. Szymczak-Workman et al.   JOURNAL OF IMMUNOLOGY

Analysis of Adhesion Molecules, Target Cells, and Role of IL-2 in Human FOXP3+ Regulatory T Cell Suppressor Function

(2009) D. Q. Tran et al.   JOURNAL OF IMMUNOLOGY

Impact of the TCR Signal on Regulatory T Cell Homeostasis, Function, and Trafficking

(2009) Joong Kyu Kim et al.   PLoS One

Ablation of SLP-76 signaling after T cell priming generates memory CD4 T cells impaired in steady-state and cytokine-driven homeostasis

(2009) N. D. Bushar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Complementation In Trans of Altered Thymocyte Development in Mice Expressing Mutant Forms of the Adaptor Molecule SLP76

(2008) Martha S. Jordan et al.   IMMUNITY

The WAVE2 complex regulates T cell receptor signaling to integrins via Abl- and CrkL–C3G-mediated activation of Rap1

(2008) Jeffrey C. Nolz et al.   JOURNAL OF CELL BIOLOGY

Foxp3+ natural regulatory T cells preferentially form aggregates on dendritic cells in vitro and actively inhibit their maturation

(2008) Y. Onishi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CTLA-4 Control over Foxp3+ Regulatory T Cell Function

(2008) K. Wing et al.   SCIENCE