Early onset combined immunodeficiency and autoimmunity in patients with loss-of-function mutation in LAT

Low level of LAT–PLC-γ1 interaction is associated with Th2 polarized differentiation: A contributing factor to the etiology of asthma

(2014) Xiaohua Peng et al.   CELLULAR IMMUNOLOGY

Palmitoylated transmembrane adaptor proteins in leukocyte signaling

(2014) Ondrej Stepanek et al.   CELLULAR SIGNALLING

Sos1 regulates sustained TCR-mediated Erk activation

(2014) Mateusz Poltorak et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Quantitative proteomics analysis of signalosome dynamics in primary T cells identifies the surface receptor CD6 as a Lat adaptor–independent TCR signaling hub

(2014) Romain Roncagalli et al.   NATURE IMMUNOLOGY

Integrative biology of T cell activation

(2014) Bernard Malissen et al.   NATURE IMMUNOLOGY

The CD3 Conformational Change in the γδ T Cell Receptor Is Not Triggered by Antigens but Can Be Enforced to Enhance Tumor Killing

(2014) Elaine P. Dopfer et al.   Cell Reports

Murine natural killer immunoreceptors use distinct proximal signaling complexes to direct cell function

(2013) R. M. May et al.   BLOOD

The Thr224Asn mutation in the VPS45 gene is associated with the congenital neutropenia and primary myelofibrosis of infancy

(2013) P. Stepensky et al.   BLOOD

Diacylglycerol Kinases: Regulated Controllers of T Cell Activation, Function, and Development

(2013) Rohan Joshi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cutting Edge: CD1d Restriction and Th1/Th2/Th17 Cytokine Secretion by Human V 3 T Cells

(2013) B. A. Mangan et al.   JOURNAL OF IMMUNOLOGY

Primary T-cell immunodeficiency with immunodysregulation caused by autosomal recessive LCK deficiency

(2012) Fabian Hauck et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Loss-of-function mutations within the IL-2 inducible kinase ITK in patients with EBV-associated lymphoproliferative diseases

(2012) R M Linka et al.   LEUKEMIA

Role of LAT in the Granule-Mediated Cytotoxicity of CD8 T Cells

(2012) C.-w. Ou-Yang et al.   MOLECULAR AND CELLULAR BIOLOGY

Paediatric Reference Values for the Peripheral T cell Compartment

(2012) E. J. H. Schatorjé et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Strength of TCR-Peptide/MHC Interactions and In Vivo T Cell Responses

(2011) E. Corse et al.   JOURNAL OF IMMUNOLOGY

The role of V 2-negative    T cells during cytomegalovirus reactivation in recipients of allogeneic stem cell transplantation

(2010) A. Knight et al.   BLOOD

Characterization of ζ-associated protein, 70 kd (ZAP70)–deficient human lymphocytes

(2010) Chaim M. Roifman et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

LAT signaling pathology: an “autoimmune” condition without T cell self-reactivity

(2010) Romain Roncagalli et al.   TRENDS IN IMMUNOLOGY

The LAT Story: A Tale of Cooperativity, Coordination, and Choreography

(2010) L. Balagopalan et al.   Cold Spring Harbor Perspectives in Biology

T Cell Activation

(2009) Jennifer E. Smith-Garvin et al.   Annual Review of Immunology

Refined characterization and reference values of the pediatric T- and B-cell compartments

(2009) R. van Gent et al.   CLINICAL IMMUNOLOGY

STAT6 Deletion Converts the Th2 Inflammatory Pathology Afflicting LatY136F Mice into a Lymphoproliferative Disorder Involving Th1 and CD8 Effector T Cells

(2009) C. Archambaud et al.   JOURNAL OF IMMUNOLOGY

Enzymatic assembly of DNA molecules up to several hundred kilobases

(2009) Daniel G Gibson et al.   NATURE METHODS

Phenotypic classification of human CD4+ T cell subsets and their differentiation

(2008) R. Okada et al.   INTERNATIONAL IMMUNOLOGY

Omenn syndrome: Inflammation in leaky severe combined immunodeficiency

(2008) Anna Villa et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Scalable signaling mediated by T cell antigen receptor–CD3 ITAMs ensures effective negative selection and prevents autoimmunity

(2008) Jeff Holst et al.   NATURE IMMUNOLOGY