Investigating the Role of the NLRP3 Inflammasome Pathway in Acute Intestinal Inflammation: Use of THP-1 Knockout Cell Lines in an Advanced Triple Culture Model

Model Complexity as Determining Factor for In Vitro Nanosafety Studies: Effects of Silver and Titanium Dioxide Nanomaterials in Intestinal Models

(2021) Angela A. M. Kämpfer et al.   Small

Fast but not furious: a streamlined selection method for genome-edited cells

(2021) Haribaskar Ramachandran et al.   Life Science Alliance

TNF-α synergises with IFN-γ to induce caspase-8-JAK1/2-STAT1-dependent death of intestinal epithelial cells

(2021) Jerzy A. Woznicki et al.   Cell Death & Disease

Characterization of increased mucus production of HT29-MTX-E12 cells grown under Semi-Wet interface with Mechanical Stimulation

(2021) Janneke Elzinga et al.   PLoS One

Muc5ac Expression Protects the Colonic Barrier in Experimental Colitis

(2020) Kristine E Olli et al.   INFLAMMATORY BOWEL DISEASES

NLRP3 inflammasome priming: A riddle wrapped in a mystery inside an enigma

(2020) Chloe M. McKee et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Investigations of acute effects of polystyrene and polyvinyl chloride micro- and nanoplastics in an advanced in vitro triple culture model of the healthy and inflamed intestine

(2020) Mathias Busch et al.   ENVIRONMENTAL RESEARCH

Anti-TNF Therapy in Crohn’s Disease

(2018) Samuel O. Adegbola et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

NLRP3 inflammasome in colitis and colitis-associated colorectal cancer

(2018) Agampodi Promoda Perera et al.   MAMMALIAN GENOME

IL-8 promotes proliferation and inhibition of apoptosis via STAT3/AKT/NF-κB pathway in prostate cancer

(2017) Yidi Guo et al.   Molecular Medicine Reports

Development of an in vitro co-culture model to mimic the human intestine in healthy and diseased state

(2017) Angela A.M. Kämpfer et al.   TOXICOLOGY IN VITRO

IL-1β induces apoptosis and autophagy via mitochondria pathway in human degenerative nucleus pulposus cells

(2017) Jieliang Shen et al.   Scientific Reports

NLRP3 inflammasome has a protective effect against oxazolone-induced colitis: a possible role in ulcerative colitis

(2016) Shigehiro Itani et al.   Scientific Reports

Differential Expression of MUC12, MUC16, and MUC20 in Patients with Active and Remission Ulcerative Colitis

(2015) Jesús K. Yamamoto-Furusho et al.   MEDIATORS OF INFLAMMATION

Silica-induced NLRP3 inflammasome activation in vitro and in rat lungs

(2014) Paul M Peeters et al.   Particle and Fibre Toxicology

Nlrp3 activation in the intestinal epithelium protects against a mucosal pathogen

(2013) G X Song-Zhao et al.   Mucosal Immunology

A clinical review of recent findings in the epidemiology of inflammatory bowel disease

(2013) Millie Long et al.   Clinical Epidemiology

Protective and Aggravating Effects of Nlrp3 Inflammasome Activation in IBD Models: Influence of Genetic and Environmental Factors

(2012) Christian Bauer et al.   DIGESTIVE DISEASES

Amino-Functionalized Polystyrene Nanoparticles Activate the NLRP3 Inflammasome in Human Macrophages

(2011) Oleg Lunov et al.   ACS Nano

NLRP6 Inflammasome Regulates Colonic Microbial Ecology and Risk for Colitis

(2011) Eran Elinav et al.   CELL

Understanding the mechanism of IL-1β secretion

(2011) Gloria Lopez-Castejon et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Recent Insights Into the Genetics of Inflammatory Bowel Disease

(2011) Judy H. Cho et al.   GASTROENTEROLOGY

The MUC13 cell-surface mucin protects against intestinal inflammation by inhibiting epithelial cell apoptosis

(2011) Y. H. Sheng et al.   GUT

Altered O-glycosylation profile of MUC2 mucin occurs in active ulcerative colitis and is associated with increased inflammation

(2011) Jessica M. Holmn Larsson et al.   INFLAMMATORY BOWEL DISEASES

Mucins in inflammatory bowel diseases and colorectal cancer

(2011) Yong H Sheng et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Intestinal homeostasis and its breakdown in inflammatory bowel disease

(2011) Kevin J. Maloy et al.   NATURE

The nuclear factor- B-interleukin-6 signalling pathway mediating vascular inflammation

(2010) A. R. Brasier   CARDIOVASCULAR RESEARCH

Triggered human mucosal T cells release tumour necrosis factor-alpha and interferon-gamma which kill human colonic epithelial cells

(2010) R. L. DEEM et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Colitis induced in mice with dextran sulfate sodium (DSS) is mediated by the NLRP3 inflammasome

(2010) C. Bauer et al.   GUT

The NLRP3 Inflammasome Protects against Loss of Epithelial Integrity and Mortality during Experimental Colitis

(2010) Md. Hasan Zaki et al.   IMMUNITY

Control of Intestinal Homeostasis, Colitis, and Colitis-Associated Colorectal Cancer by the Inflammatory Caspases

(2010) Jeremy Dupaul-Chicoine et al.   IMMUNITY

NLRP3 inflammasome plays a key role in the regulation of intestinal homeostasis

(2010) Simon A. Hirota et al.   INFLAMMATORY BOWEL DISEASES

The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer

(2010) Irving C. Allen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Organotypical tissue cultures from adult murine colon as an in vitro model of intestinal mucosa

(2008) Petra M. Bareiss et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Thickness and continuity of the adherent colonic mucus barrier in active and quiescent ulcerative colitis and Crohn’s disease

(2008) V. Strugala et al.   INTERNATIONAL JOURNAL OF CLINICAL PRACTICE

Common variants in the NLRP3 region contribute to Crohn's disease susceptibility

(2008) Alexandra-Chloé Villani et al.   NATURE GENETICS

Aberrant Expression of MUC1 Mucin in Pediatric Inflammatory Bowel Disease

(2008) Anna E. Furr et al.   PEDIATRIC AND DEVELOPMENTAL PATHOLOGY