Silica-induced NLRP3 inflammasome activation in vitro and in rat lungs

Asbestos modulates thioredoxin-thioredoxin interacting protein interaction to regulate inflammasome activation

(2014) Joyce K Thompson et al.   Particle and Fibre Toxicology

Thioredoxin/Txnip: Redoxisome, as a Redox Switch for the Pathogenesis of Diseases

(2014) Eiji Yoshihara et al.   Frontiers in Immunology

Neutralization of interleukin-1 beta attenuates silica-induced lung inflammation and fibrosis in C57BL/6 mice

(2013) Jiali Guo et al.   ARCHIVES OF TOXICOLOGY

Different Anti-Oxidant Effects of Thioredoxin 1 and Thioredoxin 2 in Retinal Epithelial Cells

(2013) Eriko Sugano et al.   CELL STRUCTURE AND FUNCTION

Bioreactivity of the crystalline silica polymorphs, quartz and cristobalite, and implications for occupational exposure limits (OELs)

(2013) Brooke T. Mossman et al.   CRITICAL REVIEWS IN TOXICOLOGY

Asbestos and erionite prime and activate the NLRP3 inflammasome that stimulates autocrine cytokine release in human mesothelial cells

(2013) Jedd M Hillegass et al.   Particle and Fibre Toxicology

Silica induces NLRP3 inflammasome activation in human lung epithelial cells

(2013) Paul M Peeters et al.   Particle and Fibre Toxicology

Potential Determinants of Coal Workers’ Pneumoconiosis, Advanced Pneumoconiosis, and Progressive Massive Fibrosis Among Underground Coal Miners in the United States, 2005–2009

(2012) A. Scott Laney et al.   AMERICAN JOURNAL OF PUBLIC HEALTH

Differential activation of the inflammasome in THP-1 cells exposed to chrysotile asbestos and Libby “six-mix” amphiboles and subsequent activation of BEAS-2B cells

(2012) Muyao Li et al.   CYTOKINE

Redox control of NLRP3 inflammasome activation in health and disease

(2012) Anna Rubartelli   JOURNAL OF LEUKOCYTE BIOLOGY

Differences in gene expression and cytokine production by crystalline vs. amorphous silica in human lung epithelial cells

(2012) Timothy N Perkins et al.   Particle and Fibre Toxicology

Molecular Pathways: Targeting Mechanisms of Asbestos and Erionite Carcinogenesis in Mesothelioma

(2011) M. Carbone et al.   CLINICAL CANCER RESEARCH

Inflammasome-Dependent Release of the Alarmin HMGB1 in Endotoxemia

(2010) M. Lamkanfi et al.   JOURNAL OF IMMUNOLOGY

Activation of the inflammasome by amorphous silica and TiO2nanoparticles in murine dendritic cells

(2010) Meike Winter et al.   Nanotoxicology

Nanoparticles activate the NLR pyrin domain containing 3 (Nlrp3) inflammasome and cause pulmonary inflammation through release of IL-1  and IL-1 

(2010) A. S. Yazdi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Thioredoxin 1 delivery as new therapeutics

(2009) Hajime Nakamura et al.   ADVANCED DRUG DELIVERY REVIEWS

Thioredoxin-interacting protein links oxidative stress to inflammasome activation

(2009) Rongbin Zhou et al.   NATURE IMMUNOLOGY

Assessing nanotoxicity in cells in vitro

(2009) Jedd M. Hillegass et al.   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

Active Caspase-1 Is a Regulator of Unconventional Protein Secretion

(2008) Martin Keller et al.   CELL

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

(2008) Veit Hornung et al.   NATURE IMMUNOLOGY

The NALP3 inflammasome is involved in the innate immune response to amyloid-β

(2008) Annett Halle et al.   NATURE IMMUNOLOGY

The Nalp3 inflammasome is essential for the development of silicosis

(2008) Suzanne L. Cassel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica

(2008) C. Dostert et al.   SCIENCE