Exploring the role of sex differences in Alzheimer's disease pathogenesis in Down syndrome
出版年份 2022 全文链接
标题
Exploring the role of sex differences in Alzheimer's disease pathogenesis in Down syndrome
作者
关键词
-
出版物
Frontiers in Neuroscience
Volume 16, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2022-08-12
DOI
10.3389/fnins.2022.954999
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Estrogen receptor α: a critical role in successful female cognitive aging
- (2021) N. E. Baumgartner et al. CLIMACTERIC
- Astrocyte-immune cell interactions in physiology and pathology
- (2021) Rafael T. Han et al. IMMUNITY
- In-depth quantitative proteomic characterization of organotypic hippocampal slice culture reveals sex-specific differences in biochemical pathways
- (2021) Simone Nardin Weis et al. Scientific Reports
- Increase of blood-brain barrier leakage is related to cognitive decline in vascular mild cognitive impairment
- (2021) Man Li et al. BMC Neurology
- The Behavioral and Psychological Symptoms of Dementia in Down Syndrome scale (BPSD-DS II): Optimization and Further Validation
- (2021) Alain D. Dekker et al. JOURNAL OF ALZHEIMERS DISEASE
- Synaptophysin‐dependent synaptobrevin‐2 trafficking at the presynapse‐Mechanism and function
- (2021) Michael A. Cousin JOURNAL OF NEUROCHEMISTRY
- Diagnostic and prognostic performance and longitudinal changes in plasma neurofilament light chain concentrations in adults with Down syndrome: a cohort study
- (2021) Maria Carmona-Iragui et al. LANCET NEUROLOGY
- Association of Apolipoprotein E ɛ4 Allele With Clinical and Multimodal Biomarker Changes of Alzheimer Disease in Adults With Down Syndrome
- (2021) Alexandre Bejanin et al. JAMA Neurology
- The Association between Sex and Risk of Alzheimer’s Disease in Adults with Down Syndrome
- (2021) Pooja Girish Mhatre et al. Journal of Clinical Medicine
- Sex differences in levels of plasma neurofilament light and total tau in adults with Down syndrome
- (2021) Lam‐Ha T Dang et al. Alzheimers & Dementia
- Menopause moderates sex differences in tau PET signal: Findings from the Framingham Study
- (2021) Rachel F. Buckley et al. Alzheimers & Dementia
- Alzheimer's disease associated with Down syndrome: a genetic form of dementia
- (2021) Juan Fortea et al. LANCET NEUROLOGY
- Health comorbidities and cognitive abilities across the lifespan in Down syndrome
- (2020) Carla M. Startin et al. Journal of Neurodevelopmental Disorders
- Down syndrome
- (2020) Stylianos E. Antonarakis et al. Nature Reviews Disease Primers
- The X Files: “The Mystery of X Chromosome Instability in Alzheimer’s Disease”
- (2020) Vladan P. Bajic et al. Frontiers in Genetics
- Microglial and Astrocytic Function in Physiological and Pathological Conditions: Estrogenic Modulation
- (2020) Andrea Crespo-Castrillo et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- APOE4 leads to blood–brain barrier dysfunction predicting cognitive decline
- (2020) Axel Montagne et al. NATURE
- Association of Factors With Elevated Amyloid Burden in Clinically Normal Older Individuals
- (2020) Reisa A. Sperling et al. JAMA Neurology
- Sex-driven modifiers of Alzheimer risk
- (2020) Aneela Rahman et al. NEUROLOGY
- Cause of death in adults with Down syndrome in the US
- (2020) Scott D. Landes et al. Disability and Health Journal
- Alzheimer‐Related Cerebrovascular Disease in Down Syndrome
- (2020) Patrick J. Lao et al. ANNALS OF NEUROLOGY
- The peri-menopause in a woman’s life: a systemic inflammatory phase that enables later neurodegenerative disease
- (2020) Micheline McCarthy et al. Journal of Neuroinflammation
- GnRH protective effects against amyloid β-induced cognitive decline: A potential role of the 17β-estradiol
- (2020) Ladan Marbouti et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Association of sleep with cognition and beta amyloid accumulation in adults with Down syndrome
- (2020) Karly A. Cody et al. NEUROBIOLOGY OF AGING
- A second X chromosome contributes to resilience in a mouse model of Alzheimer’s disease
- (2020) Emily J. Davis et al. Science Translational Medicine
- Nerve growth factor (NGF) pathway biomarkers in Down syndrome prior to and after the onset of clinical Alzheimer's disease: A paired CSF and plasma study
- (2020) Rowan Pentz et al. Alzheimers & Dementia
- Evolution of neuroinflammation across the lifespan of individuals with Down syndrome
- (2020) Lisi Flores-Aguilar et al. BRAIN
- Plasma Total-Tau and Neurofilament Light Chain as Diagnostic Biomarkers of Alzheimer’s Disease Dementia and Mild Cognitive Impairment in Adults with Down Syndrome
- (2020) Melissa E. Petersen et al. JOURNAL OF ALZHEIMERS DISEASE
- Aβ oligomers induce pathophysiological mGluR5 signaling in Alzheimer’s disease model mice in a sex-selective manner
- (2020) Khaled S. Abd-Elrahman et al. Science Signaling
- Blood–brain barrier breakdown is an early biomarker of human cognitive dysfunction
- (2019) Daniel A. Nation et al. NATURE MEDICINE
- Sex Differences in the Association of Global Amyloid and Regional Tau Deposition Measured By Positron Emission Tomography in Clinically Normal Older Adults
- (2019) Rachel F. Buckley et al. JAMA Neurology
- Astrocyte Heterogeneity: Impact to Brain Aging and Disease
- (2019) Isadora Matias et al. Frontiers in Aging Neuroscience
- Reproductive period and risk of dementia in a diverse cohort of health care members
- (2019) Paola Gilsanz et al. NEUROLOGY
- Associations between baseline amyloid, sex and APOE on subsequent tau accumulation in cerebrospinal fluid
- (2019) Rachel F. Buckley et al. NEUROBIOLOGY OF AGING
- Dementia in Down syndrome: unique insights for Alzheimer disease research
- (2019) Ira T. Lott et al. Nature Reviews Neurology
- ApoE4: an emerging therapeutic target for Alzheimer’s disease
- (2019) Mirna Safieh et al. BMC Medicine
- Comparison between amyloid-PET and CSF amyloid-β biomarkers in a clinical cohort with memory deficits
- (2019) Caroline Bouter et al. CLINICA CHIMICA ACTA
- Neurofilament light chain as a biomarker in neurological disorders
- (2019) Lorenzo Gaetani et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- White matter hyperintensities: relationship to amyloid and tau burden
- (2019) Jonathan Graff-Radford et al. BRAIN
- Diagnostic Value of Cerebrospinal Fluid Neurofilament Light Protein in Neurology
- (2019) Claire Bridel et al. JAMA Neurology
- Plasma amyloid and tau as dementia biomarkers in Down syndrome: Systematic review and meta‐analyses
- (2019) Falah Alhajraf et al. Developmental Neurobiology
- Comparison of variables associated with cerebrospinal fluid neurofilament, total-tau, and neurogranin
- (2019) Michelle M. Mielke et al. Alzheimers & Dementia
- White matter hyperintensities and their relationship to cognition: Effects of segmentation algorithm
- (2019) Meral A. Tubi et al. NEUROIMAGE
- Sex differences for major congenital heart defects in Down Syndrome: A population based study
- (2018) Michele Santoro et al. European Journal of Medical Genetics
- Epidemiology of estrogen and dementia in women with Down syndrome
- (2018) Nicole Schupf et al. FREE RADICAL BIOLOGY AND MEDICINE
- Exosomal biomarkers in Down syndrome and Alzheimer's disease
- (2018) Eric D. Hamlett et al. FREE RADICAL BIOLOGY AND MEDICINE
- Down syndrome, beta-amyloid and neuroimaging
- (2018) Elizabeth Head et al. FREE RADICAL BIOLOGY AND MEDICINE
- Association of Plasma Neurofilament Light Chain with Neocortical Amyloid-β Load and Cognitive Performance in Cognitively Normal Elderly Participants
- (2018) Pratishtha Chatterjee et al. JOURNAL OF ALZHEIMERS DISEASE
- Microglia-Mediated Synapse Loss in Alzheimer's Disease
- (2018) Lawrence Rajendran et al. JOURNAL OF NEUROSCIENCE
- Sex differences in Alzheimer disease — the gateway to precision medicine
- (2018) Maria Teresa Ferretti et al. Nature Reviews Neurology
- Neuroimaging and other modalities to assess Alzheimer's disease in Down syndrome
- (2018) Natalie Neale et al. NeuroImage-Clinical
- Inflammation: the link between comorbidities, genetics, and Alzheimer’s disease
- (2018) Estella A. Newcombe et al. Journal of Neuroinflammation
- Sex differences in Alzheimer’s disease and common neuropathologies of aging
- (2018) Shahram Oveisgharan et al. ACTA NEUROPATHOLOGICA
- Blood-brain barrier breakdown, neuroinflammation, and cognitive decline in older adults
- (2018) Gene L. Bowman et al. Alzheimers & Dementia
- Microbleeds and Cerebral Amyloid Angiopathy in the Brains of People with Down Syndrome with Alzheimer’s Disease
- (2018) Alex M. Helman et al. JOURNAL OF ALZHEIMERS DISEASE
- Peripheral immune system in aging and Alzheimer’s disease
- (2018) Wei Cao et al. Molecular Neurodegeneration
- In vivo modeling of human neuron dynamics and Down syndrome
- (2018) Raquel Real et al. SCIENCE
- PET Imaging of Tau Pathology and Relationship to Amyloid, Longitudinal MRI, and Cognitive Change in Down Syndrome: Results from the Down Syndrome Biomarker Initiative (DSBI)
- (2017) Michael S. Rafii et al. JOURNAL OF ALZHEIMERS DISEASE
- Down Syndrome, Partial Trisomy 21, and Absence of Alzheimer’s Disease: The Role of APP
- (2017) Eric Doran et al. JOURNAL OF ALZHEIMERS DISEASE
- The Down syndrome brain in the presence and absence of fibrillar β-amyloidosis
- (2017) Tiina Annus et al. NEUROBIOLOGY OF AGING
- Brain-predicted age in Down syndrome is associated with beta amyloid deposition and cognitive decline
- (2017) James H. Cole et al. NEUROBIOLOGY OF AGING
- Cerebrospinal fluid biomarkers for Alzheimer's and vascular disease vary by age, gender, and APOE genotype in cognitively normal adults
- (2017) Ge Li et al. Alzheimers Research & Therapy
- Cerebrovascular pathology in Down syndrome and Alzheimer disease
- (2017) Elizabeth Head et al. Acta Neuropathologica Communications
- Early-Versus Late-Onset Alzheimer's Disease: More than Age Alone
- (2017) Esther L.G.E. Koedam et al. JOURNAL OF ALZHEIMERS DISEASE
- Early Age at Menopause is Associated with Increased risk of Dementia and Mortality in Women with Down Syndrome
- (2017) Antonia M.W. Coppus et al. JOURNAL OF ALZHEIMERS DISEASE
- Sex biology contributions to vulnerability to Alzheimer's disease: A think tank convened by the Women's Alzheimer's Research Initiative
- (2016) Heather M. Snyder et al. Alzheimers & Dementia
- The effects of normal aging on amyloid-β deposition in nondemented adults with Down syndrome as imaged by carbon 11–labeled Pittsburgh compound B
- (2016) Patrick J. Lao et al. Alzheimers & Dementia
- Mosaic Loss of Chromosome Y in Blood Is Associated with Alzheimer Disease
- (2016) Jan P. Dumanski et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Cerebrovascular contributions to aging and Alzheimer's disease in Down syndrome
- (2016) Donna M. Wilcock et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Estrogen protects the blood–brain barrier from inflammation-induced disruption and increased lymphocyte trafficking
- (2016) E. Maggioli et al. BRAIN BEHAVIOR AND IMMUNITY
- Sex differences in the association between AD biomarkers and cognitive decline
- (2016) Mary Ellen I. Koran et al. Brain Imaging and Behavior
- The Prevalence and Incidence of Dementia Due to Alzheimer’s Disease: a Systematic Review and Meta-Analysis
- (2016) Kirsten M. Fiest et al. CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES
- Cerebrospinal fluid tau, neurogranin, and neurofilament light in Alzheimer's disease
- (2016) Niklas Mattsson et al. EMBO Molecular Medicine
- Epigenetic dysregulation in the developing Down syndrome cortex
- (2016) Nady El Hajj et al. Epigenetics
- Corticotropin-releasing factor overexpression gives rise to sex differences in Alzheimer’s disease-related signaling
- (2016) D A Bangasser et al. MOLECULAR PSYCHIATRY
- A two decade dementia incidence comparison from the Cognitive Function and Ageing Studies I and II
- (2016) F. E. Matthews et al. Nature Communications
- Estrogen receptor β in Alzheimer’s disease: From mechanisms to therapeutics
- (2015) Liqin Zhao et al. AGEING RESEARCH REVIEWS
- Estrogen receptors in the central nervous system and their implication for dopamine-dependent cognition in females
- (2015) Anne Almey et al. HORMONES AND BEHAVIOR
- Low Testosterone Level and Risk of Alzheimer’s Disease in the Elderly Men: a Systematic Review and Meta-Analysis
- (2015) Wenshan Lv et al. MOLECULAR NEUROBIOLOGY
- Down syndrome individuals with Alzheimer's disease have a distinct neuroinflammatory phenotype compared to sporadic Alzheimer's disease
- (2015) Donna M. Wilcock et al. NEUROBIOLOGY OF AGING
- Everyday executive functions in Down syndrome from early childhood to young adulthood: evidence for both unique and shared characteristics compared to youth with sex chromosome trisomy (XXX and XXY)
- (2015) Nancy Raitano Lee et al. Frontiers in Behavioral Neuroscience
- Sex modifies theAPOE-related risk of developing Alzheimer disease
- (2014) Andre Altmann et al. ANNALS OF NEUROLOGY
- Estrogen receptor agonists for attenuation of neuroinflammation and neurodegeneration
- (2014) Mrinmay Chakrabarti et al. BRAIN RESEARCH BULLETIN
- Alterations of ectonucleotidases and acetylcholinesterase activities in lymphocytes of Down syndrome subjects: Relation with inflammatory parameters
- (2014) Rodrigo Rodrigues et al. CLINICA CHIMICA ACTA
- X chromosome regulation: diverse patterns in development, tissues and disease
- (2014) Xinxian Deng et al. NATURE REVIEWS GENETICS
- Apolipoprotein E: Structure and function in lipid metabolism, neurobiology, and Alzheimer's diseases
- (2014) Yadong Huang et al. NEUROBIOLOGY OF DISEASE
- A Starring Role for Microglia in Brain Sex Differences
- (2014) Kathryn M. Lenz et al. NEUROSCIENTIST
- Genomic integrity of the Y chromosome sequence-tagged-sites in infertile and Down syndrome Jordanian males
- (2013) S. R. Yasin et al. ANDROLOGIA
- Atypical aging in down syndrome
- (2013) Warren B. Zigman Developmental Disabilities Research Reviews
- Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy
- (2013) Chia-Chen Liu et al. Nature Reviews Neurology
- Neuroserpin up-regulation in the Alzheimer’s disease brain is associated with elevated thyroid hormone receptor-β1 and HuD expression
- (2013) Bobban Subhadra et al. NEUROCHEMISTRY INTERNATIONAL
- Age at surgical menopause influences cognitive decline and Alzheimer pathology in older women
- (2013) R. Bove et al. NEUROLOGY
- Imaging brain amyloid in nondemented young adults with Down syndrome using Pittsburgh compound B
- (2012) Benjamin L. Handen et al. Alzheimers & Dementia
- Neuroprotection and Estrogen Receptors
- (2012) James W. Simpkins et al. NEUROENDOCRINOLOGY
- Using Positron Emission Tomography and Carbon 11–Labeled Pittsburgh Compound B to Image Brain Fibrillar β-Amyloid in Adults With Down Syndrome
- (2011) Jennifer Landt ARCHIVES OF NEUROLOGY
- Genes that escape from X inactivation
- (2011) Joel B. Berletch et al. HUMAN GENETICS
- Timing of hormone therapy and dementia: The critical window theory revisited
- (2010) Rachel A. Whitmer et al. ANNALS OF NEUROLOGY
- Molecular mechanisms of neurodegeneration in Alzheimer's disease
- (2010) L. Crews et al. HUMAN MOLECULAR GENETICS
- Association between male gender and cortical Lewy body pathology in large autopsy series
- (2010) Peter T. Nelson et al. JOURNAL OF NEUROLOGY
- Hashimoto’s Thyroiditis in Down’s Syndrome: Clinical Presentation and Evolution
- (2008) Galina Popova et al. HORMONE RESEARCH
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