Genetic loss of function of Ptbp1 does not induce glia-to-neuron conversion in retina

Turning lead into gold: reprogramming retinal cells to cure blindness

(2021) Seth Blackshaw et al.   JOURNAL OF CLINICAL INVESTIGATION

Therapeutically viable generation of neurons with antisense oligonucleotide suppression of PTB

(2021) Roy Maimon et al.   NATURE NEUROSCIENCE

Revisiting astrocyte to neuron conversion with lineage tracing in vivo

(2021) Lei-Lei Wang et al.   CELL

Glia-to-Neuron Conversion by CRISPR-CasRx Alleviates Symptoms of Neurological Disease in Mice

(2020) Haibo Zhou et al.   CELL

A Widespread Neurogenic Potential of Neocortical Astrocytes Is Induced by Injury

(2020) Margherita Zamboni et al.   Cell Stem Cell

Reversing a model of Parkinson’s disease with in situ converted nigral neurons

(2020) Hao Qian et al.   NATURE

Developmental Attenuation of Neuronal Apoptosis by Neural-Specific Splicing of Bak1 Microexon

(2020) Lin Lin et al.   NEURON

Gene regulatory networks controlling vertebrate retinal regeneration

(2020) Thanh Hoang et al.   SCIENCE

In vivo glial trans‐differentiation for neuronal replacement and functional recovery in central nervous system

(2020) Cheng Qian et al.   FEBS Journal

Comprehensive Integration of Single-Cell Data

(2019) Tim Stuart et al.   CELL

Direct Lineage Reprogramming for Brain Repair: Breakthroughs and Challenges

(2019) Rory Vignoles et al.   TRENDS IN MOLECULAR MEDICINE

Stimulation of functional neuronal regeneration from Müller glia in adult mice

(2017) Nikolas L. Jorstad et al.   NATURE

Induction of functional dopamine neurons from human astrocytes in vitro and mouse astrocytes in a Parkinson's disease model

(2017) Pia Rivetti di Val Cervo et al.   NATURE BIOTECHNOLOGY

PTBP1 and PTBP2 Serve Both Specific and Redundant Functions in Neuronal Pre-mRNA Splicing

(2016) John K. Vuong et al.   Cell Reports

PTBP1 and PTBP2 Repress Nonconserved Cryptic Exons

(2016) Jonathan P. Ling et al.   Cell Reports

Small Molecules Efficiently Reprogram Human Astroglial Cells into Functional Neurons

(2015) Lei Zhang et al.   Cell Stem Cell

Ascl1 Converts Dorsal Midbrain Astrocytes into Functional Neurons In Vivo

(2015) Y. Liu et al.   JOURNAL OF NEUROSCIENCE

Epigenomic Signatures of Neuronal Diversity in the Mammalian Brain

(2015) Alisa Mo et al.   NEURON

Neuronal Transgene Expression in Dominant-Negative SNARE Mice

(2014) T. Fujita et al.   JOURNAL OF NEUROSCIENCE

Direct Conversion of Fibroblasts to Neurons by Reprogramming PTB-Regulated MicroRNA Circuits

(2013) Yuanchao Xue et al.   CELL

In vivo reprogramming of astrocytes to neuroblasts in the adult brain

(2013) Wenze Niu et al.   NATURE CELL BIOLOGY

PTB Deficiency Causes the Loss of Adherens Junctions in the Dorsal Telencephalon and Leads to Lethal Hydrocephalus

(2012) Takayuki Shibasaki et al.   CEREBRAL CORTEX

Injury-independent induction of reactive gliosis in retina by loss of function of the LIM homeodomain transcription factor Lhx2

(2012) J. de Melo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Direct generation of functional dopaminergic neurons from mouse and human fibroblasts

(2011) Massimiliano Caiazzo et al.   NATURE

Polypyrimidine tract-binding protein is essential for early mouse development and embryonic stem cell proliferation

(2009) Masaki Shibayama et al.   FEBS Journal