Therapeutic effects of sulforaphane in ulcerative colitis: effect on antioxidant activity, mitochondrial biogenesis and DNA polymerization

The Attenuation of Chronic Ulcerative Colitis by (R)-salbutamol in Repeated DSS-Induced Mice

(2022) Liangjun Deng et al.   Oxidative Medicine and Cellular Longevity

Eat Your Broccoli: Oxidative Stress, NRF2, and Sulforaphane in Chronic Kidney Disease

(2021) Scott E. Liebman et al.   Nutrients

Sulforaphane Improves Lipid Metabolism by Enhancing Mitochondrial Function and Biogenesis In Vivo and In Vitro

(2021) Peng Lei et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Next-generation multimodality of nutrigenomic cancer therapy: sulforaphane in combination with acetazolamide actively target bronchial carcinoid cancer in disabling the PI3K/Akt/mTOR survival pathway and inducing apoptosis

(2021) Reza Bayat Mokhtari et al.   Oncotarget

Preventive Effect of Lycopene in Dextran Sulfate Sodium-Induced Ulcerative Colitis Mice through the Regulation of TLR4/TRIF/NF-κB Signaling Pathway and Tight Junctions

(2021) Yaping Li et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

mTOR inhibitor PP242 increases antitumor activity of sulforaphane by blocking Akt/mTOR pathway in esophageal squamous cell carcinoma

(2021) Zhaoming Lu et al.   MOLECULAR BIOLOGY REPORTS

MUC2 and related bacterial factors: Therapeutic targets for ulcerative colitis

(2021) Dianbo Yao et al.   EBioMedicine

Sulforaphane: A Broccoli Bioactive Phytocompound with Cancer Preventive Potential

(2021) Anna E. Kaiser et al.   Cancers

Cherry Polyphenol Extract Ameliorated Dextran Sodium Sulfate-Induced Ulcerative Colitis in Mice by Suppressing Wnt/β-Catenin Signaling Pathway

(2021) Fuhua Li et al.   Foods

FA-97, a New Synthetic Caffeic Acid Phenethyl Ester Derivative, Ameliorates DSS-Induced Colitis Against Oxidative Stress by Activating Nrf2/HO-1 Pathway

(2020) Yu Mei et al.   Frontiers in Immunology

Chronic Sulforaphane Administration Inhibits Resistance to the mTOR-Inhibitor Everolimus in Bladder Cancer Cells

(2020) Saira Justin et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Sulforaphane alter the microbiota and mitigate colitis severity on mice ulcerative colitis induced by DSS

(2020) Yan Zhang et al.   AMB Express

Preclinical Efficacy and Involvement of AKT, mTOR, and ERK Kinases in the Mechanism of Sulforaphane against Endometrial Cancer

(2020) Rajani Rai et al.   Cancers

Emerging views of mitophagy in immunity and autoimmune diseases

(2019) Ye Xu et al.   Autophagy

Sulfoaphane - role in aging and neurodegeneration

(2019) Roberto Santín-Márquez et al.   GeroScience

SIRT1/PGC-1 pathway activation triggers autophagy/mitophagy and attenuates oxidative damage in intestinal epithelial cells

(2019) Danyang Liang et al.   BIOCHIMIE

Inhibition of PDE4 protects neurons against oxygen-glucose deprivation-induced endoplasmic reticulum stress through activation of the Nrf-2/HO-1 pathway

(2019) Bingtian Xu et al.   Redox Biology

Effects of Alpinetin on Intestinal Barrier Function, Inflammation and Oxidative Stress in Dextran Sulfate Sodium-Induced Ulcerative Colitis Mice

(2018) Yue Tan et al.   AMERICAN JOURNAL OF THE MEDICAL SCIENCES

Natural History of Adult Ulcerative Colitis in Population-based Cohorts: A Systematic Review

(2018) Mathurin Fumery et al.   Clinical Gastroenterology and Hepatology

Lightly Cooked Broccoli Is as Effective as Raw Broccoli in Mitigating Dextran Sulfate Sodium-Induced Colitis in Mice

(2018) Yanling Wang et al.   Nutrients

Sulforaphane Alleviates Lipopolysaccharide-induced Spatial Learning and Memory Dysfunction in Mice: The Role of BDNF-mTOR Signaling Pathway

(2018) Jie Gao et al.   NEUROSCIENCE

PCNA and JNK1-Stat3 pathways respectively promotes and inhibits diabetes-associated centrosome amplification by targeting at the ROCK1/14-3-3σ complex in human colon cancer HCT116 cells

(2018) Yu Cheng Lu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Broccoli-Derived Nanoparticle Inhibits Mouse Colitis by Activating Dendritic Cell AMP-Activated Protein Kinase

(2017) Zhongbin Deng et al.   MOLECULAR THERAPY

Increased seizure susceptibility and other toxicity symptoms following acute sulforaphane treatment in mice

(2017) Katarzyna Socała et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Markers of inflammation and influence of nitric oxide on platelet activation in the course of ulcerative colitis

(2017) Beata Gawrońska et al.   Oncotarget

Nitric oxide as a potential biomarker in inflammatory bowel disease

(2017) Nesina Avdagić et al.   Bosnian Journal of Basic Medical Sciences

Carvedilol promotes mitochondrial biogenesis by regulating the PGC-1/TFAM pathway in human umbilical vein endothelial cells (HUVECs)

(2016) Kai Yao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

mTORC1 and mTORC2 Kinase Signaling and Glucose Metabolism Drive Follicular Helper T Cell Differentiation

(2016) Hu Zeng et al.   IMMUNITY

The effect of sulforaphane on the cell cycle, apoptosis and expression of cyclin D1 and p21 in the A549 non-small cell lung cancer cell line

(2016) AGNIESZKA ŻURYŃ et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Gastroprotective effects of sulforaphane and thymoquinone against acetylsalicylic acid–induced gastric ulcer in rats

(2016) Sezgin Zeren et al.   JOURNAL OF SURGICAL RESEARCH

Sulforaphane protects against rotenone-induced neurotoxicity in vivo: Involvement of the mTOR, Nrf2 and autophagy pathways

(2016) Qian Zhou et al.   Scientific Reports

Shenling Baizhu San supresses colitis associated colorectal cancer through inhibition of epithelial-mesenchymal transition and myeloid-derived suppressor infiltration

(2015) Xiaochang Lin et al.   BMC Complementary and Alternative Medicine

Sulforaphane Attenuates Muscle Inflammation in Dystrophin-deficientmdxMice via NF-E2-related Factor 2 (Nrf2)-mediated Inhibition of NF-κB Signaling Pathway

(2015) Cheng-Cao Sun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Vitamin A exerts its antiinflammatory activities in colitis through preservation of mitochondrial activity

(2015) Ram Reifen et al.   NUTRITION

The importance of antioxidants which play the role in cellular response against oxidative/nitrosative stress: current state

(2015) Ergul Belge Kurutas   Nutrition Journal

Sulforaphane Protects against Cardiovascular Disease via Nrf2 Activation

(2015) Yang Bai et al.   Oxidative Medicine and Cellular Longevity

Modulation of mitochondrial functions by the indirect antioxidant sulforaphane: A seemingly contradictory dual role and an integrative hypothesis

(2013) Mario Negrette-Guzmán et al.   FREE RADICAL BIOLOGY AND MEDICINE

DSS-induced acute colitis in C57BL/6 mice is mitigated by sulforaphane pre-treatment

(2013) Anika E. Wagner et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Mitochondria and Tumor Progression in Ulcerative Colitis

(2013) Cigdem Himmetoglu Ussakli et al.   JNCI-Journal of the National Cancer Institute

Mitochondrial Reactive Oxygen Species Promote Epidermal Differentiation and Hair Follicle Development

(2013) R. B. Hamanaka et al.   Science Signaling

Expression of interleukin-22/STAT3 signaling pathway in ulcerative colitis and related carcinogenesis

(2013) Lian-Zhen Yu   WORLD JOURNAL OF GASTROENTEROLOGY

Development and verification of sulforaphane extraction method in cabbage (Brassica oleracea L. var. capitata) and broccoli (Brassica oleracea L. var. italica Planch.)

(2012) Zhansheng Li   Journal of Medicinal Plants Research

Mammalian transcription factor A is a core component of the mitochondrial transcription machinery

(2012) Y. Shi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Frequent Truncating Mutation of TFAM Induces Mitochondrial DNA Depletion and Apoptotic Resistance in Microsatellite-Unstable Colorectal Cancer

(2011) J. Guo et al.   CANCER RESEARCH

Modulation of Longevity and Tissue Homeostasis by the Drosophila PGC-1 Homolog

(2011) Michael Rera et al.   Cell Metabolism

New Biomarkers for Monitoring the Levels of Isothiocyanates in Humans

(2010) Anoop Kumar et al.   CHEMICAL RESEARCH IN TOXICOLOGY