The renal lineage factor PAX8 controls oncogenic signalling in kidney cancer

Pan-cancer analysis of whole genomes

(2020)   NATURE

The landscape of viral associations in human cancers

(2020) Marc Zapatka et al.   NATURE GENETICS

Index and biological spectrum of human DNase I hypersensitive sites

(2020) Wouter Meuleman et al.   NATURE

Pervasive chromosomal instability and karyotype order in tumour evolution

(2020) Thomas B. K. Watkins et al.   NATURE

The GTEx Consortium atlas of genetic regulatory effects across human tissues

(2020)   SCIENCE

HIF-1α and HIF-2α differently regulate tumour development and inflammation of clear cell renal cell carcinoma in mice

(2020) Rouven Hoefflin et al.   Nature Communications

A KLF6-driven transcriptional network links lipid homeostasis and tumour growth in renal carcinoma

(2019) Saiful E. Syafruddin et al.   Nature Communications

Tissue-specificity in cancer: The rule, not the exception

(2019) Kevin M. Haigis et al.   SCIENCE

Pan-cancer whole-genome analyses of metastatic solid tumours

(2019) Peter Priestley et al.   NATURE

PAX8 activates metabolic genes via enhancer elements in Renal Cell Carcinoma

(2019) Melusine Bleu et al.   Nature Communications

Deterministic Evolutionary Trajectories Influence Primary Tumor Growth: TRACERx Renal

(2018) Samra Turajlic et al.   CELL

A quantitative mass spectrometry-based approach to monitor the dynamics of endogenous chromatin-associated protein complexes

(2018) Evangelia K. Papachristou et al.   Nature Communications

NF-κB–Dependent Lymphoid Enhancer Co-option Promotes Renal Carcinoma Metastasis

(2018) Paulo Rodrigues et al.   Cancer Discovery

Endogenous retroviral signatures predict immunotherapy response in clear cell renal cell carcinoma

(2018) Christof C. Smith et al.   JOURNAL OF CLINICAL INVESTIGATION

The PRIDE database and related tools and resources in 2019: improving support for quantification data

(2018) Yasset Perez-Riverol et al.   NUCLEIC ACIDS RESEARCH

The chromatin accessibility landscape of primary human cancers

(2018) M. Ryan Corces et al.   SCIENCE

Computational correction of copy number effect improves specificity of CRISPR–Cas9 essentiality screens in cancer cells

(2017) Robin M Meyers et al.   NATURE GENETICS

Genome-wide association study identifies multiple risk loci for renal cell carcinoma

(2017) Ghislaine Scelo et al.   Nature Communications

VHL Deficiency Drives Enhancer Activation of Oncogenes in Clear Cell Renal Cell Carcinoma

(2017) Xiaosai Yao et al.   Cancer Discovery

Multiple renal cancer susceptibility polymorphisms modulate the HIF pathway

(2017) Steffen Grampp et al.   PLoS Genetics

Capture‐C reveals preformed chromatin interactions between HIF‐binding sites and distant promoters

(2016) James L Platt et al.   EMBO REPORTS

Direct reprogramming of fibroblasts into renal tubular epithelial cells by defined transcription factors

(2016) Michael M. Kaminski et al.   NATURE CELL BIOLOGY

A zebrafish melanoma model reveals emergence of neural crest identity during melanoma initiation

(2016) C. K. Kaufman et al.   SCIENCE

Genetic variation at the 8q24.21 renal cancer susceptibility locus affects HIF binding to a MYC enhancer

(2016) Steffen Grampp et al.   Nature Communications

Metastatic Competence Can Emerge with Selection of Preexisting Oncogenic Alleles without a Need of New Mutations

(2015) Leni S. Jacob et al.   CANCER RESEARCH

Structural integration in hypoxia-inducible factors

(2015) Dalei Wu et al.   NATURE

DNA-dependent formation of transcription factor pairs alters their binding specificity

(2015) Arttu Jolma et al.   NATURE

CRISPR interference (CRISPRi) for sequence-specific control of gene expression

(2013) Matthew H Larson et al.   Nature Protocols

Sox10 promotes the formation and maintenance of giant congenital naevi and melanoma

(2012) Olga Shakhova et al.   NATURE CELL BIOLOGY

Common genetic variants at the 11q13.3 renal cancer susceptibility locus influence binding of HIF to an enhancer of cyclin D1 expression

(2012) Johannes Schödel et al.   NATURE GENETICS

Epigenetic expansion of VHL-HIF signal output drives multiorgan metastasis in renal cancer

(2012) Sakari Vanharanta et al.   NATURE MEDICINE

Genome-wide association study of renal cell carcinoma identifies two susceptibility loci on 2p21 and 11q13.3

(2010) Mark P Purdue et al.   NATURE GENETICS

HIF-α Effects on c-Myc Distinguish Two Subtypes of Sporadic VHL-Deficient Clear Cell Renal Carcinoma

(2008) John D. Gordan et al.   CANCER CELL