标题
Structural integration in hypoxia-inducible factors
作者
关键词
-
出版物
NATURE
Volume 524, Issue 7565, Pages 303-308
出版商
Springer Nature
发表日期
2015-08-04
DOI
10.1038/nature14883
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Coiled-coil Coactivators Play a Structural Role Mediating Interactions in Hypoxia-inducible Factor Heterodimerization
- (2015) Yirui Guo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Targeting hypoxia signalling for the treatment of ischaemic and inflammatory diseases
- (2014) Holger K. Eltzschig et al. NATURE REVIEWS DRUG DISCOVERY
- COSMIC: exploring the world's knowledge of somatic mutations in human cancer
- (2014) Simon A. Forbes et al. NUCLEIC ACIDS RESEARCH
- Deciphering key features in protein structures with the new ENDscript server
- (2014) Xavier Robert et al. NUCLEIC ACIDS RESEARCH
- ThePDB_REDOserver for macromolecular structure model optimization
- (2014) Robbie P. Joosten et al. IUCrJ
- Hypoxia-Inducible Factor 1 and Cardiovascular Disease
- (2013) Gregg L. Semenza Annual Review of Physiology
- Deletions of chromosomes 3p and 14q molecularly subclassify clear cell renal cell carcinoma
- (2013) Nils Kroeger et al. CANCER
- The Exomes of the NCI-60 Panel: A Genomic Resource for Cancer Biology and Systems Pharmacology
- (2013) O. D. Abaan et al. CANCER RESEARCH
- HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations
- (2013) Gregg L. Semenza JOURNAL OF CLINICAL INVESTIGATION
- Development of Inhibitors of the PAS-B Domain of the HIF-2α Transcription Factor
- (2013) Jamie L. Rogers et al. JOURNAL OF MEDICINAL CHEMISTRY
- A Cyclic Peptide Inhibitor of HIF-1 Heterodimerization That Inhibits Hypoxia Signaling in Cancer Cells
- (2013) Elena Miranda et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Structure and Dimerization Properties of the Aryl Hydrocarbon Receptor PAS-A Domain
- (2013) D. Wu et al. MOLECULAR AND CELLULAR BIOLOGY
- Allosteric inhibition of hypoxia inducible factor-2 with small molecules
- (2013) Thomas H Scheuermann et al. Nature Chemical Biology
- Integrated molecular analysis of clear-cell renal cell carcinoma
- (2013) Yusuke Sato et al. NATURE GENETICS
- Regulating the ARNT/TACC3 Axis: Multiple Approaches to Manipulating Protein/Protein Interactions with Small Molecules
- (2012) Yirui Guo et al. ACS Chemical Biology
- Hypoxia-Inducible Factors in Physiology and Medicine
- (2012) Gregg L. Semenza CELL
- Intermolecular recognition revealed by the complex structure of human CLOCK-BMAL1 basic helix-loop-helix domains with E-box DNA
- (2012) Zixi Wang et al. CELL RESEARCH
- The transcriptional landscape and mutational profile of lung adenocarcinoma
- (2012) J.-S. Seo et al. GENOME RESEARCH
- Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma
- (2012) Cécile Guichard et al. NATURE GENETICS
- Identification of Cys255 in HIF-1α as a novel site for development of covalent inhibitors of HIF-1α/ARNT PasB domain protein-protein interaction
- (2012) Rosa Cardoso et al. PROTEIN SCIENCE
- Crystal Structure of the Heterodimeric CLOCK:BMAL1 Transcriptional Activator Complex
- (2012) N. Huang et al. SCIENCE
- Novel links between HIFs, type 2 diabetes, and metabolic syndrome
- (2012) Christian M. Girgis et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy
- (2012) Gregg L. Semenza TRENDS IN PHARMACOLOGICAL SCIENCES
- Roles of the human hypoxia-inducible factor (HIF)-3α variants in the hypoxia response
- (2011) Minna Heikkilä et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Exactly the Same but Different: Promiscuity and Diversity in the Molecular Mechanisms of Action of the Aryl Hydrocarbon (Dioxin) Receptor
- (2011) Michael S. Denison et al. TOXICOLOGICAL SCIENCES
- Genetic and Functional Studies Implicate HIF1 as a 14q Kidney Cancer Suppressor Gene
- (2011) C. Shen et al. Cancer Discovery
- Features and development ofCoot
- (2010) P. Emsley et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- PHENIX: a comprehensive Python-based system for macromolecular structure solution
- (2010) Paul D. Adams et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Ligand-Binding PAS Domains in a Genomic, Cellular, and Structural Context
- (2010) Jonathan T. Henry et al. Annual Review of Microbiology
- Mammalian Per-Arnt-Sim Proteins in Environmental Adaptation
- (2010) Brian E. McIntosh et al. Annual Review of Physiology
- Casein kinase 1 regulates human hypoxia-inducible factor HIF-1
- (2010) A. Kalousi et al. JOURNAL OF CELL SCIENCE
- MolProbity: all-atom structure validation for macromolecular crystallography
- (2009) Vincent B. Chen et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Principles of Ligand Binding within a Completely Buried Cavity in HIF2α PAS-B
- (2009) Jason Key et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics
- (2009) G L Semenza ONCOGENE
- Artificial ligand binding within the HIF2 PAS-B domain of the HIF2 transcription factor
- (2009) T. H. Scheuermann et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Acriflavine inhibits HIF-1 dimerization, tumor growth, and vascularization
- (2009) K. Lee et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structure and Signaling Mechanism of Per-ARNT-Sim Domains
- (2009) Andreas Möglich et al. STRUCTURE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now