The Tryptophan Catabolite or Kynurenine Pathway in Alzheimer’s Disease: A Systematic Review and Meta-Analysis

Inflammation and nitro-oxidative stress in current suicidal attempts and current suicidal ideation: a systematic review and meta-analysis

(2022) Asara Vasupanrajit et al.   MOLECULAR PSYCHIATRY

The Kynurenine Pathway and Kynurenine 3-Monooxygenase Inhibitors

(2022) Tamera D. Hughes et al.   MOLECULES

The tryptophan catabolite or kynurenine pathway’s role in major depression

(2022) Abbas F. Almulla et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

The tryptophan catabolite or kynurenine pathway in schizophrenia: meta-analysis reveals dissociations between central, serum, and plasma compartments

(2022) Abbas F. Almulla et al.   MOLECULAR PSYCHIATRY

Metabolic phenotyping reveals a reduction in the bioavailability of serotonin and kynurenine pathway metabolites in both the urine and serum of individuals living with Alzheimer’s disease

(2021) Luke Whiley et al.   Alzheimers Research & Therapy

Implication of Nicotinamide Adenine Dinucleotide Phosphate (NADPH) Oxidase and Its Inhibitors in Alzheimer’s Disease Murine Models

(2021) Leticia Guadalupe Fragoso-Morales et al.   Antioxidants

Inflammation, Negative Affect, and Amyloid Burden in Alzheimer’s Disease: Insights from the Kynurenine Pathway

(2021) Auriel A. Willette et al.   BRAIN BEHAVIOR AND IMMUNITY

Neuroplasticity and depression: Rewiring the brain's networks through pharmacological therapy (Review)

(2021) Ioana Rădulescu et al.   Experimental and Therapeutic Medicine

Mitochondrial dysfunction, oxidative stress, neuroinflammation, and metabolic alterations in the progression of Alzheimer’s disease: A meta-analysis of in vivo magnetic resonance spectroscopy studies

(2021) Tao Song et al.   AGEING RESEARCH REVIEWS

Suicide attempts are associated with activated immune-inflammatory, nitro-oxidative, and neurotoxic pathways: A systematic review and meta-analysis

(2021) Asara Vasupanrajit et al.   JOURNAL OF AFFECTIVE DISORDERS

Gram-negative bacteria and their lipopolysaccharides in Alzheimer’s disease: pathologic roles and therapeutic implications

(2021) Hyeon soo Kim et al.   Translational Neurodegeneration

Kynurenic Acid Levels are Increased in the CSF of Alzheimer’s Disease Patients

(2020) Marta González-Sánchez et al.   Biomolecules

Serum albumin and beta-amyloid deposition in the human brain

(2020) Jee Wook Kim et al.   NEUROLOGY

Inflammatory markers in Alzheimer’s disease and mild cognitive impairment: a meta-analysis and systematic review of 170 studies

(2019) Xue-Ning Shen et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Age‐ and disease‐specific changes of the kynurenine pathway in Parkinson’s and Alzheimer’s disease

(2019) Freek J. H. Sorgdrager et al.   JOURNAL OF NEUROCHEMISTRY

Correlation between plasma and CSF concentrations of kynurenine pathway metabolites in Alzheimer's disease and relationship to amyloid-β and tau

(2019) Kelly R. Jacobs et al.   NEUROBIOLOGY OF AGING

Systemic and central nervous system metabolic alterations in Alzheimer’s disease

(2019) Vera van der Velpen et al.   Alzheimers Research & Therapy

Alzheimer’s Disease: Recent Concepts on the Relation of Mitochondrial Disturbances, Excitotoxicity, Neuroinflammation, and Kynurenines

(2018) Dénes Zádori et al.   JOURNAL OF ALZHEIMERS DISEASE

Could Alzheimer’s Disease Originate in the Periphery and If So How So?

(2018) Gerwyn Morris et al.   MOLECULAR NEUROBIOLOGY

Alterations in serum kynurenine pathway metabolites in individuals with high neocortical amyloid-β load: A pilot study

(2018) Pratishtha Chatterjee et al.   Scientific Reports

Kynurenine Pathway Metabolites in Alzheimer’s Disease

(2017) Lasse Melvaer Giil et al.   JOURNAL OF ALZHEIMERS DISEASE

Deficit, but Not Nondeficit, Schizophrenia Is Characterized by Mucosa-Associated Activation of the Tryptophan Catabolite (TRYCAT) Pathway with Highly Specific Increases in IgA Responses Directed to Picolinic, Xanthurenic, and Quinolinic Acid

(2017) Buranee Kanchanatawan et al.   MOLECULAR NEUROBIOLOGY

Deficit Schizophrenia Is Characterized by Defects in IgM-Mediated Responses to Tryptophan Catabolites (TRYCATs): a Paradigm Shift Towards Defects in Natural Self-Regulatory Immune Responses Coupled with Mucosa-Derived TRYCAT Pathway Activation

(2017) Buranee Kanchanatawan et al.   MOLECULAR NEUROBIOLOGY

Secretory Products of the Human GI Tract Microbiome and Their Potential Impact on Alzheimer's Disease (AD): Detection of Lipopolysaccharide (LPS) in AD Hippocampus

(2017) Yuhai Zhao et al.   Frontiers in Cellular and Infection Microbiology

The Many Neuroprogressive Actions of Tryptophan Catabolites (TRYCATs) that may be Associated with the Pathophysiology of Neuro-Immune Disorders

(2016) Gerwyn Morris et al.   CURRENT PHARMACEUTICAL DESIGN

Gram-negative bacterial molecules associate with Alzheimer disease pathology

(2016) Xinhua Zhan et al.   NEUROLOGY

Oxidant/Antioxidant Imbalance and the Risk of Alzheimer's Disease

(2015) Ahmed Moneim   Current Alzheimer Research

Neuroinflammation in Alzheimer's disease

(2015) Michael T Heneka et al.   LANCET NEUROLOGY

Lowered Levels of Carbonyl Proteins after Vitamin B Supplementation in Patients with Mild Cognitive Impairment and Alzheimer's Disease

(2015) Paulus S. Rommer et al.   Neurodegenerative Diseases

Estimating the sample mean and standard deviation from the sample size, median, range and/or interquartile range

(2015) Xiang Wan et al.   BMC Medical Research Methodology

IFN-γ and TNF-α Are Involved During Alzheimer Disease Progression and Correlate with Nitric Oxide Production: A Study in Algerian Patients

(2014) Mourad Belkhelfa et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Body Fluid Cytokine Levels in Mild Cognitive Impairment and Alzheimer’s Disease: a Comparative Overview

(2014) Frederic Brosseron et al.   MOLECULAR NEUROBIOLOGY

Oxidative stress in blood in Alzheimer's disease and mild cognitive impairment: A meta-analysis

(2013) M. Schrag et al.   NEUROBIOLOGY OF DISEASE

Quinolinic Acid: An Endogenous Neurotoxin with Multiple Targets

(2013) Rafael Lugo-Huitrón et al.   Oxidative Medicine and Cellular Longevity

Plasma cortisol in Alzheimer’s disease with or without depressive symptoms

(2013) Jiří Raboch   MEDICAL SCIENCE MONITOR

Amyloid imaging in cognitively normal individuals, at-risk populations and preclinical Alzheimer's disease

(2013) Gaël Chételat et al.   NeuroImage-Clinical

Increased 3-Hydroxykynurenine serum concentrations differentiate Alzheimer’s disease patients from controls

(2012) Markus J. Schwarz et al.   EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE

Amyloid Precursor Protein Processing and Alzheimer's Disease

(2011) Richard J. O'Brien et al.   Annual Review of Neuroscience

Protective effects of tryptophan on neuro-inflammation in rats after administering lipopolysaccharide

(2011) A.R. Del Angel-Meza et al.   BIOMEDICINE & PHARMACOTHERAPY

Kynurenine and its metabolites in Alzheimer's disease patients

(2010) E Gulaj et al.   Advances in Medical Sciences

The new ‘5-HT’ hypothesis of depression: Cell-mediated immune activation induces indoleamine 2,3-dioxygenase, which leads to lower plasma tryptophan and an increased synthesis of detrimental tryptophan catabolites (TRYCATs), both of which contribute to the onset of depression

(2010) M. Maes et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

A review on the oxidative and nitrosative stress (O&NS) pathways in major depression and their possible contribution to the (neuro)degenerative processes in that illness

(2010) Michael Maes et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

5-Hydroxyanthranilic Acid, a Tryptophan Metabolite, Generates Oxidative Stress and Neuronal Death via p38 Activation in Cultured Cerebellar Granule Neurones

(2009) Andrew J. Smith et al.   NEUROTOXICITY RESEARCH

The Excitotoxin Quinolinic Acid Induces Tau Phosphorylation in Human Neurons

(2009) Abdur Rahman et al.   PLoS One

Circulating endotoxin and systemic immune activation in sporadic amyotrophic lateral sclerosis (sALS)

(2008) Rongzhen Zhang et al.   JOURNAL OF NEUROIMMUNOLOGY

Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease

(2008) P. Hemachandra Reddy et al.   TRENDS IN MOLECULAR MEDICINE