Regulated Expression of lpxC Allows for Reduction of Endotoxicity in Bordetella pertussis

Variation, Modification and Engineering of Lipid A in Endotoxin of Gram-Negative Bacteria

(2021) Kazuyoshi Kawahara   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

YejM Modulates Activity of the YciM/FtsH Protease Complex To Prevent Lethal Accumulation of Lipopolysaccharide

(2020) Randi L. Guest et al.   mBio

An Essential Membrane Protein Modulates the Proteolysis of LpxC to Control Lipopolysaccharide Synthesis in Escherichia coli

(2020) Elayne M. Fivenson et al.   mBio

Structure of the essential inner membrane lipopolysaccharide–PbgA complex

(2020) Thomas Clairfeuille et al.   NATURE

Border Control: Regulating LPS Biogenesis

(2020) Randi L. Guest et al.   TRENDS IN MICROBIOLOGY

Shortening the Lipid A Acyl Chains of Bordetella pertussis Enables Depletion of Lipopolysaccharide Endotoxic Activity

(2020) Jesús Arenas et al.   Vaccines

Regulation of the First Committed Step in Lipopolysaccharide Biosynthesis Catalyzed by LpxC Requires the Essential Protein LapC (YejM) and HslVU Protease

(2020) Daria Biernacka et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Fundamental differences in physiology of Bordetella pertussis dependent on the two-component system Bvg revealed by gene essentiality studies

(2020) Thomas Belcher et al.   Microbial Genomics

Regulated Assembly of LPS, Its Structural Alterations and Cellular Response to LPS Defects

(2019) Gracjana Klein et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Pushing the envelope: LPS modifications and their consequences

(2019) Brent W. Simpson et al.   NATURE REVIEWS MICROBIOLOGY

In Vivo Gene Essentiality and Metabolism in Bordetella pertussis

(2019) Laura A. Gonyar et al.   mSphere

Pertussis Prevention: Reasons for Resurgence, and Differences in the Current Acellular Pertussis Vaccines

(2019) Susanna Esposito et al.   Frontiers in Immunology

Pertussis vaccines and protective immunity

(2019) Parul Kapil et al.   CURRENT OPINION IN IMMUNOLOGY

Robust suppression of lipopolysaccharide deficiency in Acinetobacter baumannii by growth in minimal medium

(2019) Emma Nagy et al.   JOURNAL OF BACTERIOLOGY

The Escherichia coli Phospholipase PldA Regulates Outer Membrane Homeostasis via Lipid Signaling

(2018) Kerrie L. May et al.   mBio

Phospholipid retention in the absence of asymmetry strengthens the outer membrane permeability barrier to last-resort antibiotics

(2018) Matthew J. Powers et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Disruption of lipid homeostasis in the Gram-negative cell envelope activates a novel cell death pathway

(2016) Holly A. Sutterlin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A novel mechanism for the biogenesis of outer membrane vesicles in Gram-negative bacteria

(2016) Sandro Roier et al.   Nature Communications

Modulating endotoxin activity by combinatorial bioengineering of meningococcal lipopolysaccharide

(2016) Afshin Zariri et al.   Scientific Reports

Bordetella pertussis outer membrane vesicle vaccine confers equal efficacy in mice with milder inflammatory responses compared to a whole-cell vaccine

(2016) René H. M. Raeven et al.   Scientific Reports

Outer-membrane vesicles from Gram-negative bacteria: biogenesis and functions

(2015) Carmen Schwechheimer et al.   NATURE REVIEWS MICROBIOLOGY

Assembly of Lipopolysaccharide inEscherichia coliRequires the Essential LapB Heat Shock Protein

(2014) Gracjana Klein et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ght Protein of Neisseria meningitidis Is Involved in the Regulation of Lipopolysaccharide Biosynthesis

(2013) F. Putker et al.   JOURNAL OF BACTERIOLOGY

Bexsero

(2012) Andrew R. Gorringe et al.   Human Vaccines & Immunotherapeutics

An improved whole cell pertussis vaccine with reduced content of endotoxin

(2012) Waldely Dias et al.   Human Vaccines & Immunotherapeutics

Colistin Resistance in Acinetobacter baumannii Is Mediated by Complete Loss of Lipopolysaccharide Production

(2010) J. H. Moffatt et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Control of Lipopolysaccharide Biosynthesis by FtsH-Mediated Proteolysis of LpxC Is Conserved in Enterobacteria but Not in All Gram-Negative Bacteria

(2010) S. Langklotz et al.   JOURNAL OF BACTERIOLOGY

The Bacterial Cell Envelope

(2010) T. J. Silhavy et al.   Cold Spring Harbor Perspectives in Biology

Immunogenicity of a Whole-Cell Pertussis Vaccine with Low Lipopolysaccharide Content in Infants

(2009) T. Q. Zorzeto et al.   Clinical and Vaccine Immunology

The structural basis of lipopolysaccharide recognition by the TLR4–MD-2 complex

(2009) Beom Seok Park et al.   NATURE