Indole-3-propionic acid alleviates ischemic brain injury in a mouse middle cerebral artery occlusion model

The Role of Gut Microbiota in an Ischemic Stroke

(2021) Ryszard Pluta et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Propionic Acid Shapes the Multiple Sclerosis Disease Course by an Immunomodulatory Mechanism

(2020) Alexander Duscha et al.   CELL

Gut Microbiota-Derived Short-Chain Fatty Acids Promote Post-Stroke Recovery in Aged Mice

(2020) Juneyoung Lee et al.   CIRCULATION RESEARCH

Immune responses to stroke: mechanisms, modulation, and therapeutic potential

(2020) Costantino Iadecola et al.   JOURNAL OF CLINICAL INVESTIGATION

Gut microbiota-derived indole 3-propionic acid protects against radiation toxicity via retaining acyl-CoA-binding protein

(2020) Hui-wen Xiao et al.   Microbiome

Dysbiosis, gut barrier dysfunction and inflammation in dementia: a pilot study

(2020) Vanessa Stadlbauer et al.   BMC Geriatrics

Gut microbiota–specific IgA+ B cells traffic to the CNS in active multiple sclerosis

(2020) Anne-Katrin Pröbstel et al.   Science Immunology

Sex-specific effects of microbiome perturbations on cerebral Aβ amyloidosis and microglia phenotypes

(2019) Hemraj B. Dodiya et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Immunomodulatory Therapeutic Strategies in Stroke

(2019) Kyle Malone et al.   Frontiers in Pharmacology

Bile acid metabolites control TH17 and Treg cell differentiation

(2019) Saiyu Hang et al.   NATURE

Alterations of the gut microbiota with antibiotics protects dopamine neuron loss and improve motor deficits in a pharmacological rodent model of Parkinson's disease

(2019) Dimitri N. Koutzoumis et al.   EXPERIMENTAL NEUROLOGY

Microbiota-Derived Indole Metabolites Promote Human and Murine Intestinal Homeostasis through Regulation of Interleukin-10 Receptor

(2018) Erica E. Alexeev et al.   AMERICAN JOURNAL OF PATHOLOGY

Peripheral Th17/Treg imbalance in elderly patients with ischemic stroke

(2018) Sanam Dolati et al.   NEUROLOGICAL SCIENCES

An insight into intestinal mucosal microbiota disruption after stroke

(2018) Dragana Stanley et al.   Scientific Reports

Nonalcoholic fatty liver disease is associated with dysbiosis independent of body mass index and insulin resistance

(2018) Hannah E. Da Silva et al.   Scientific Reports

Associations of serum indolepropionic acid, a gut microbiota metabolite, with type 2 diabetes and low-grade inflammation in high-risk individuals

(2018) Marjo Tuomainen et al.   Nutrition & Diabetes

Microbial tryptophan catabolites in health and disease

(2018) Henrik M. Roager et al.   Nature Communications

The role of the microbiome in NAFLD and NASH

(2018) Aleksandra A Kolodziejczyk et al.   EMBO Molecular Medicine

Stroke target identification guided by astrocyte transcriptome analysis

(2018) Cordula Rakers et al.   GLIA

Bacteria engineered to produce IL-22 in intestine induce expression of REG3G to reduce ethanol-induced liver disease in mice

(2018) Tim Hendrikx et al.   GUT

A tryptophan metabolite of the skin microbiota attenuates inflammation in patients with atopic dermatitis through the aryl hydrocarbon receptor

(2018) Jinlei Yu et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Brain regulatory T cells suppress astrogliosis and potentiate neurological recovery

(2018) Minako Ito et al.   NATURE

Homeostatic Immunity and the Microbiota

(2017) Yasmine Belkaid et al.   IMMUNITY

Infiltration and persistence of lymphocytes during late-stage cerebral ischemia in middle cerebral artery occlusion and photothrombotic stroke models

(2017) Yan Feng et al.   Journal of Neuroinflammation

Plasma microbiome-modulated indole- and phenyl-derived metabolites associate with advanced atherosclerosis and postoperative outcomes

(2017) Cori A. Cason et al.   JOURNAL OF VASCULAR SURGERY

Stroke

(2017) Graeme J Hankey   LANCET

A gut bacterial pathway metabolizes aromatic amino acids into nine circulating metabolites

(2017) Dylan Dodd et al.   NATURE

Lactobacillus reuteriinduces gut intraepithelial CD4+CD8αα+T cells

(2017) Luisa Cervantes-Barragan et al.   SCIENCE

Microbiota Dysbiosis Controls the Neuroinflammatory Response after Stroke

(2016) V. Singh et al.   JOURNAL OF NEUROSCIENCE

Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and central nervous system inflammation via the aryl hydrocarbon receptor

(2016) Veit Rothhammer et al.   NATURE MEDICINE

Commensal microbiota affects ischemic stroke outcome by regulating intestinal γδ T cells

(2016) Corinne Benakis et al.   NATURE MEDICINE

Astrocytes: a central element in neurological diseases

(2015) Milos Pekny et al.   ACTA NEUROPATHOLOGICA

Use of 16S rRNA Gene-Targeted Group-Specific Primers for Real-Time PCR Analysis of Predominant Bacteria in Mouse Feces

(2015) Yun-Wen Yang et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Functional Role of Regulatory Lymphocytes in Stroke: Facts and Controversies

(2015) A. Liesz et al.   STROKE

Symbiotic Bacterial Metabolites Regulate Gastrointestinal Barrier Function via the Xenobiotic Sensor PXR and Toll-like Receptor 4

(2014) Madhukumar Venkatesh et al.   IMMUNITY

Regulation of astrocyte activation by glycolipids drives chronic CNS inflammation

(2014) Lior Mayo et al.   NATURE MEDICINE

Tryptophan Catabolites from Microbiota Engage Aryl Hydrocarbon Receptor and Balance Mucosal Reactivity via Interleukin-22

(2013) Teresa Zelante et al.   IMMUNITY

Boosting Regulatory T Cells Limits Neuroinflammation in Permanent Cortical Stroke

(2013) A. Liesz et al.   JOURNAL OF NEUROSCIENCE

Stroke and the immune system: from pathophysiology to new therapeutic strategies

(2011) Richard Macrez et al.   LANCET NEUROLOGY

The immunology of stroke: from mechanisms to translation

(2011) Costantino Iadecola et al.   NATURE MEDICINE

Inducible Foxp3+ regulatory T-cell development by a commensal bacterium of the intestinal microbiota

(2010) J. L. Round et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Investigation of Human Blood Plasma Sample Preparation for Performing Metabolomics Using Ultrahigh Performance Liquid Chromatography/Mass Spectrometry

(2009) Stephen J. Bruce et al.   ANALYTICAL CHEMISTRY

Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria

(2009) Ivaylo I. Ivanov et al.   CELL

Indole-3-propionic acid attenuates neuronal damage and oxidative stress in the ischemic hippocampus

(2009) In Koo Hwang et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Regulatory T cells are key cerebroprotective immunomodulators in acute experimental stroke

(2009) Arthur Liesz et al.   NATURE MEDICINE

Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites

(2009) W. R. Wikoff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA