Gut microbiota–specific IgA+ B cells traffic to the CNS in active multiple sclerosis

Integrated single cell analysis of blood and cerebrospinal fluid leukocytes in multiple sclerosis

(2020) David Schafflick et al.   Nature Communications

A Genomic Toolkit for the Mechanistic Dissection of Intractable Human Gut Bacteria

(2020) Jordan E. Bisanz et al.   Cell Host & Microbe

Mucosal or systemic microbiota exposures shape the B cell repertoire

(2020) Hai Li et al.   NATURE

A pathogenic and clonally expanded B cell transcriptome in active multiple sclerosis

(2020) Akshaya Ramesh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Silent Progression in Disease Activity-Free Relapsing Multiple Sclerosis

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Recirculating Intestinal IgA-Producing Cells Regulate Neuroinflammation via IL-10

(2019) Olga L. Rojas et al.   CELL

Misfolded SOD1 inclusions in patients with mutations in C9orf72 and other ALS/FTD-associated genes

(2019) Karin Forsberg et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Association of Intrathecal Immunoglobulin G Synthesis With Disability Worsening in Multiple Sclerosis

(2019) Christiane Gasperi et al.   JAMA Neurology

The neuropathology of fatal encephalomyelitis in human Borna virus infection

(2019) Friederike Liesche et al.   ACTA NEUROPATHOLOGICA

Neuronal vulnerability and multilineage diversity in multiple sclerosis

(2019) Lucas Schirmer et al.   NATURE

The antibody/microbiota interface in health and disease

(2019) Delphine Sterlin et al.   Mucosal Immunology

Analysis of the B cell receptor repertoire in six immune-mediated diseases

(2019) R. J. M. Bashford-Rogers et al.   NATURE

IgA and the intestinal microbiota: the importance of being specific

(2019) Oliver Pabst et al.   Mucosal Immunology

Anti-commensal Ig—from enormous diversity to clear function

(2019) Tim Rollenske et al.   Mucosal Immunology

B cells in autoimmune and neurodegenerative central nervous system diseases

(2019) Joseph J. Sabatino et al.   NATURE REVIEWS NEUROSCIENCE

Multiple sclerosis

(2018) Alan J Thompson et al.   LANCET

Diagnosis of multiple sclerosis: 2017 revisions of the McDonald criteria

(2018) Alan J Thompson et al.   LANCET NEUROLOGY

Cross-specificity of protective human antibodies against Klebsiella pneumoniae LPS O-antigen

(2018) Tim Rollenske et al.   NATURE IMMUNOLOGY

Chronic Meningitis Investigated via Metagenomic Next-Generation Sequencing

(2018) Michael R. Wilson et al.   JAMA Neurology

IgA Responses to Microbiota

(2018) Jeffrey J. Bunker et al.   IMMUNITY

Definition and Consensus Diagnostic Criteria for Neurosarcoidosis

(2018) Barney J. Stern et al.   JAMA Neurology

Multiple Sclerosis-Associated Changes in the Composition and Immune Functions of Spore-Forming Bacteria

(2018) Egle Cekanaviciute et al.   mSystems

Increased cerebrospinal fluid albumin and immunoglobulin A fractions forecast cortical atrophy and longitudinal functional deterioration in relapsing-remitting multiple sclerosis

(2017) Julia Kroth et al.   Multiple Sclerosis Journal

Inflammation-induced IgA+ cells dismantle anti-liver cancer immunity

(2017) Shabnam Shalapour et al.   NATURE

The Role of the Gut Microbiome in Multiple Sclerosis Risk and Progression: Towards Characterization of the “MS Microbiome”

(2017) Anne-Katrin Pröbstel et al.   Neurotherapeutics

Ocrelizumab versus Interferon Beta-1a in Relapsing Multiple Sclerosis

(2017) Stephen L. Hauser et al.   NEW ENGLAND JOURNAL OF MEDICINE

Gut bacteria from multiple sclerosis patients modulate human T cells and exacerbate symptoms in mouse models

(2017) Egle Cekanaviciute et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gut microbiota from multiple sclerosis patients enables spontaneous autoimmune encephalomyelitis in mice

(2017) Kerstin Berer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IgA-coatedE. colienriched in Crohn’s disease spondyloarthritis promote TH17-dependent inflammation

(2017) Monica Viladomiu et al.   Science Translational Medicine

Increased cerebrospinal fluid albumin and immunoglobulin A fractions forecast cortical atrophy and longitudinal functional deterioration in relapsing-remitting multiple sclerosis

(2017) Julia Kroth et al.   Multiple Sclerosis Journal

Associations between the gut microbiota and host immune markers in pediatric multiple sclerosis and controls

(2016) Helen Tremlett et al.   BMC Neurology

Comparison of three analytical platforms for quantification of the neurofilament light chain in blood samples: ELISA, electrochemiluminescence immunoassay and Simoa

(2016) Jens Kuhle et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Gut microbiota in early pediatric multiple sclerosis: a case−control study

(2016) H. Tremlett et al.   EUROPEAN JOURNAL OF NEUROLOGY

A human gut ecosystem protects against C. difficile disease by targeting TcdA

(2016) Sarah Lynn Martz et al.   JOURNAL OF GASTROENTEROLOGY

Altered intestinal permeability in patients with relapsing–remitting multiple sclerosis: A pilot study

(2016) Maria Chiara Buscarinu et al.   Multiple Sclerosis Journal

Neonatal gut microbiota associates with childhood multisensitized atopy and T cell differentiation

(2016) Kei E Fujimura et al.   NATURE MEDICINE

Analysis of bacterial-surface-specific antibodies in body fluids using bacterial flow cytometry

(2016) Kathrin Moor et al.   Nature Protocols

High-quality full-length immunoglobulin profiling with unique molecular barcoding

(2016) M A Turchaninova et al.   Nature Protocols

Identifying species of symbiont bacteria from the human gut that, alone, can induce intestinal Th17 cells in mice

(2016) Tze Guan Tan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alterations of the human gut microbiome in multiple sclerosis

(2016) Sushrut Jangi et al.   Nature Communications

Altered intestinal permeability in patients with relapsing–remitting multiple sclerosis: A pilot study

(2016) Maria Chiara Buscarinu et al.   Multiple Sclerosis Journal

High-affinity monoclonal IgA regulates gut microbiota and prevents colitis in mice

(2016) Shinsaku Okai et al.   Nature Microbiology

Error filtering, pair assembly and error correction for next-generation sequencing reads

(2015) Robert C. Edgar et al.   BIOINFORMATICS

Gut Microbiota in Multiple Sclerosis

(2015) Brandi L. Cantarel et al.   JOURNAL OF INVESTIGATIVE MEDICINE

Anti-MOG antibodies are present in a subgroup of patients with a neuromyelitis optica phenotype

(2015) Anne-Katrin Pröbstel et al.   Journal of Neuroinflammation

MiXCR: software for comprehensive adaptive immunity profiling

(2015) Dmitriy A Bolotin et al.   NATURE METHODS

Functional characterization of IgA-targeted bacterial taxa from undernourished Malawian children that produce diet-dependent enteropathy

(2015) Andrew L. Kau et al.   Science Translational Medicine

On the origin of Neurostatus

(2015) Ludwig Kappos et al.   Multiple Sclerosis and Related Disorders

Dysbiosis in the Gut Microbiota of Patients with Multiple Sclerosis, with a Striking Depletion of Species Belonging to Clostridia XIVa and IV Clusters

(2015) Sachiko Miyake et al.   PLoS One

Differential loss of KIR4.1 immunoreactivity in multiple sclerosis lesions

(2014) Lucas Schirmer et al.   ANNALS OF NEUROLOGY

Immunoglobulin A Coating Identifies Colitogenic Bacteria in Inflammatory Bowel Disease

(2014) Noah W. Palm et al.   CELL

IgA Targets the Troublemakers

(2014) W. Zac Stephens et al.   Cell Host & Microbe

Atacicept in multiple sclerosis (ATAMS): a randomised, placebo-controlled, double-blind, phase 2 trial

(2014) Ludwig Kappos et al.   LANCET NEUROLOGY

B cells populating the multiple sclerosis brain mature in the draining cervical lymph nodes

(2014) J. N. H. Stern et al.   Science Translational Medicine

Predictive functional profiling of microbial communities using 16S rRNA marker gene sequences

(2013) Morgan G I Langille et al.   NATURE BIOTECHNOLOGY

IgBLAST: an immunoglobulin variable domain sequence analysis tool

(2013) Jian Ye et al.   NUCLEIC ACIDS RESEARCH

Feasibility of the Use of Combinatorial Chemokine Arrays to Study Blood and CSF in Multiple Sclerosis

(2013) Keith R. Edwards et al.   PLoS One

FLASH: fast length adjustment of short reads to improve genome assemblies

(2011) T. Magoc et al.   BIOINFORMATICS

Meningeal inflammation is widespread and linked to cortical pathology in multiple sclerosis

(2011) Owain W. Howell et al.   BRAIN

Commensal microbiota and myelin autoantigen cooperate to trigger autoimmune demyelination

(2011) Kerstin Berer et al.   NATURE

An automated tool for detection of FLAIR-hyperintense white-matter lesions in Multiple Sclerosis

(2011) Paul Schmidt et al.   NEUROIMAGE

Antibodies to MOG are transient in childhood acute disseminated encephalomyelitis

(2011) A. K. Probstel et al.   NEUROLOGY

QIIME allows analysis of high-throughput community sequencing data

(2010) J Gregory Caporaso et al.   NATURE METHODS

Inducible Foxp3+ regulatory T-cell development by a commensal bacterium of the intestinal microbiota

(2010) J. L. Round et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Blood-borne human plasma cells in steady state are derived from mucosal immune responses

(2008) H. E. Mei et al.   BLOOD

B-Cell Depletion with Rituximab in Relapsing–Remitting Multiple Sclerosis

(2008) Stephen L. Hauser et al.   NEW ENGLAND JOURNAL OF MEDICINE