Effects of Metformin on Renal Function, Cardiac Function, and Inflammatory Response in Diabetic Nephropathy and Its Protective Mechanism

Metformin treatment in late middle age improves cognitive function with alleviation of microglial activation and enhancement of autophagy in the hippocampus

(2021) Maheedhar Kodali et al.   AGING CELL

Metformin: current clinical applications in nondiabetic patients with cancer

(2020) Kailin Chen et al.   Aging-US

Metformin Reduces the Senescence of Renal Tubular Epithelial Cells in Diabetic Nephropathy via the MBNL1/miR-130a-3p/STAT3 Pathway

(2020) Xue Jiang et al.   Oxidative Medicine and Cellular Longevity

Prevalence of Diabetic Nephropathy among Patients with Type 2 Diabetes Mellitus in China: A Meta-Analysis of Observational Studies

(2020) Xin-Xin Zhang et al.   Journal of Diabetes Research

An updated overview of diabetic nephropathy: Diagnosis, prognosis, treatment goals and latest guidelines

(2020) Nicholas M. Selby et al.   DIABETES OBESITY & METABOLISM

The Metformin Mechanism on Gluconeogenesis and AMPK Activation: The Metabolite Perspective

(2020) Loranne Agius et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Pathogenic Pathways and Therapeutic Approaches Targeting Inflammation in Diabetic Nephropathy

(2020) Sandra Rayego-Mateos et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A Novel Approach Based on Metabolomics Coupled With Intestinal Flora Analysis and Network Pharmacology to Explain the Mechanisms of Action of Bekhogainsam Decoction in the Improvement of Symptoms of Streptozotocin-Induced Diabetic Nephropathy in Mice

(2020) Xianglong Meng et al.   Frontiers in Pharmacology

Mechanisms of action of metformin in type 2 diabetes: Effects on mitochondria and leukocyte-endothelium interactions

(2020) Nadezda Apostolova et al.   Redox Biology

Metformin and colorectal cancer: a systematic review, meta-analysis and meta-regression

(2020) Cheng-Ann Winston Ng et al.   INTERNATIONAL JOURNAL OF COLORECTAL DISEASE

Human umbilical cord-derived mesenchymal stem cells prevent the progression of early diabetic nephropathy through inhibiting inflammation and fibrosis

(2020) E Xiang et al.   Stem Cell Research & Therapy

Insights into predicting diabetic nephropathy using urinary biomarkers

(2020) Naseer Ullah Khan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Metformin, chronic nephropathy and lactic acidosis: a multi-faceted issue for the nephrologist

(2020) Filippo Mariano et al.   JOURNAL OF NEPHROLOGY

Autophagy blockade mechanistically links proton pump inhibitors to worsened diabetic nephropathy and aborts the renoprotection of metformin/enalapril

(2020) Dalia Kamal Mostafa et al.   LIFE SCIENCES

Tripterygium and its extracts for diabetic nephropathy: Efficacy and pharmacological mechanisms

(2019) Wei-jun Huang et al.   BIOMEDICINE & PHARMACOTHERAPY

Metformin alleviates oxidative stress and enhances autophagy in diabetic kidney disease via AMPK/SIRT1-FoxO1 pathway

(2019) Huiwen Ren et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Metformin-associated lactic acidosis: Current perspectives on causes and risk

(2016) Ralph DeFronzo et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Metformin—mode of action and clinical implications for diabetes and cancer

(2014) Ida Pernicova et al.   Nature Reviews Endocrinology