Metformin Reduces the Senescence of Renal Tubular Epithelial Cells in Diabetic Nephropathy via the MBNL1/miR-130a-3p/STAT3 Pathway

STAT3 Regulates the Onset of Oxidant-Induced Senescence in Lung Fibroblasts

(2019) David W Waters et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

The Alcohol Extract of Coreopsis tinctoria Nutt Ameliorates Diabetes and Diabetic Nephropathy in db/db Mice through miR-192/miR-200b and PTEN/AKT and ZEB2/ECM Pathways

(2019) Shunjie Yu et al.   Biomed Research International

Inhibition of lymphatic proliferation by the selective VEGFR-3 inhibitor SAR131675 ameliorates diabetic nephropathy in db/db mice

(2019) Seun Deuk Hwang et al.   Cell Death & Disease

Scutellarin Exerts Hypoglycemic and Renal Protective Effects in db/db Mice via the Nrf2/HO-1 Signaling Pathway

(2019) Yange Liu et al.   Oxidative Medicine and Cellular Longevity

FXR1 promotes the malignant biological behavior of glioma cells via stabilizing MIR17HG

(2019) Shuo Cao et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

MiR-320a induces diabetic nephropathy via inhibiting MafB

(2019) Mengying He et al.   Aging-US

MiR-455-3p suppresses renal fibrosis through repression of ROCK2 expression in diabetic nephropathy

(2018) Jian Wu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Nifuroxazide, a STAT3 inhibitor, mitigates inflammatory burden and protects against diabetes-induced nephropathy in rats

(2018) Eman Said et al.   CHEMICO-BIOLOGICAL INTERACTIONS

LINC01287/miR-298/STAT3 feedback loop regulates growth and the epithelial-to-mesenchymal transition phenotype in hepatocellular carcinoma cells

(2018) Yichao Mo et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

The protective effects of metformin in an in vitro model of aging 3T3 fibroblast under the high glucose conditions

(2018) Tugba Soydas et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

Systematic Discovery of RNA Binding Proteins that Regulate MicroRNA Levels

(2018) Julia K. Nussbacher et al.   MOLECULAR CELL

Oxidative stress mediated by lipid metabolism contributes to high glucose-induced senescence in retinal pigment epithelium

(2018) Qingqiu Chen et al.   FREE RADICAL BIOLOGY AND MEDICINE

Variations in MicroRNA-25 Expression Influence the Severity of Diabetic Kidney Disease

(2017) Yunshuang Liu et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

MBNL expression in autoregulatory feedback loops

(2017) Patryk Konieczny et al.   RNA Biology

Spatial and Temporal Control of Senescence

(2017) Yoko Ito et al.   TRENDS IN CELL BIOLOGY

Overexpression of miR‑130a‑3p/301a‑3p attenuates high glucose‑induced MPC5 podocyte dysfunction through suppression of TNF‑α signaling

(2017) Yan Jiang et al.   Experimental and Therapeutic Medicine

Reverse Expression of Aging-Associated Molecules through Transfection of miRNAs to Aged Mice

(2017) Jung-Hee Kim et al.   Molecular Therapy-Nucleic Acids

hnRNP A1 antagonizes cellular senescence and senescence-associated secretory phenotype via regulation of SIRT1 mRNA stability

(2016) Hui Wang et al.   AGING CELL

Muscleblind-like 1 suppresses breast cancer metastatic colonization and stabilizes metastasis suppressor transcripts

(2016) Lisa Fish et al.   GENES & DEVELOPMENT

Nephroprotective Effects of Metformin in Diabetic Nephropathy

(2016) Sreenithya Ravindran et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Cellular senescence in renal ageing and disease

(2016) Ines Sturmlechner et al.   Nature Reviews Nephrology

Egg antigen p40 of Schistosoma japonicum promotes senescence in activated hepatic stellate cells by activation of the STAT3/p53/p21 pathway

(2016) Jinling Chen et al.   Cell Death & Disease

Impact of ER stress-regulated ATF4/p16 signaling on the premature senescence of renal tubular epithelial cells in diabetic nephropathy

(2015) Jun Liu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Metformin Suppresses Pancreatic Tumor Growth With Inhibition of NFκB/STAT3 Inflammatory Signaling

(2015) Xiang-Lin Tan et al.   PANCREAS

The ACE2/Apelin Signaling, MicroRNAs, and Hypertension

(2015) Lai-Jiang Chen et al.   International Journal of Hypertension

A Novel Function of MicroRNA 130a-3p in Hepatic Insulin Sensitivity and Liver Steatosis

(2014) F. Xiao et al.   DIABETES

Hyperosmolarity induced by high glucose promotes senescence in human glomerular mesangial cells

(2014) Maria del Nogal et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

miRNA-130b is required for the ERK/FOXM1 pathway activation-mediated protective effects of isosorbide dinitrate against mesenchymal stem cell senescence induced by high glucose

(2014) JIANFENG XU et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

QKI deficiency promotes FoxO1 mediated nitrosative stress and endoplasmic reticulum stress contributing to increased vulnerability to ischemic injury in diabetic heart

(2014) Wangang Guo et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Metformin modulates hyperglycaemia-induced endothelial senescence and apoptosis through SIRT1

(2013) Gnanapragasam Arunachalam et al.   BRITISH JOURNAL OF PHARMACOLOGY

Compound loss of muscleblind-like function in myotonic dystrophy

(2013) Kuang-Yung Lee et al.   EMBO Molecular Medicine

Mechanisms Involved in the Protective Effects of Metformin Against Nonalcoholic Fatty Liver Disease

(2012) V. J. Barbero-Becerra et al.   CURRENT MEDICINAL CHEMISTRY

Cellular and molecular mechanisms of metformin: an overview

(2011) Benoit Viollet et al.   CLINICAL SCIENCE

Autoregulated Splicing ofmuscleblind-like 1 (MBNL1) Pre-mRNA

(2011) Devika P. Gates et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Post-transcriptional Up-regulation of Tsc-22 by Ybx1, a Target of miR-216a, Mediates TGF-β-induced Collagen Expression in Kidney Cells

(2010) Mitsuo Kato et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Global estimates of the prevalence of diabetes for 2010 and 2030

(2009) J.E. Shaw et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Progression of diabetic nephropathy in type 1 diabetic patients

(2008) Behzad Najafian et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

RNA-binding proteins and post-transcriptional gene regulation

(2008) Tina Glisovic et al.   FEBS LETTERS

Podocyte-Specific Loss of Functional MicroRNAs Leads to Rapid Glomerular and Tubular Injury

(2008) J. Ho et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY