Autophagy: an adaptive physiological countermeasure to cellular senescence and ischaemia/reperfusion-associated cardiac arrhythmias

Activation of autophagy improved the neurologic outcome after cardiopulmonary resuscitation in rats

(2016) Xin Li et al.   AMERICAN JOURNAL OF EMERGENCY MEDICINE

Type-2 diabetes increases autophagy in the human heart through promotion of Beclin-1 mediated pathway

(2016) Pujika Emani Munasinghe et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Is “Attenuation of Oxidative Stress” Helpful to Understand the Mechanism of Remote Ischemic Preconditioning in Cardiac Surgery?

(2016) Funda Yildirim et al.   JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA

Pinocembrin reduces cardiac arrhythmia and infarct size in rats subjected to acute myocardial ischemia/reperfusion

(2015) Anusorn Lungkaphin et al.   Applied Physiology Nutrition and Metabolism

Autophagic adaptations in diabetic cardiomyopathy differ between type 1 and type 2 diabetes

(2015) Hiromitsu Kanamori et al.   Autophagy

The interplay between autophagy and the ubiquitin–proteasome system in cardiac proteotoxicity

(2015) Changhua Wang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The Effect of Autophagy on Inflammation Cytokines in Renal Ischemia/Reperfusion Injury

(2015) Haibin Ling et al.   INFLAMMATION

Combining Epinephrine and Esmolol Attenuates Excessive Autophagy and Mitophagy in Rat Cardiomyocytes After Cardiac Arrest

(2015) Jian Lu et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Heat shock protein responses to aging and proteotoxicity in the olfactory bulb

(2015) Tyler S. Crum et al.   JOURNAL OF NEUROCHEMISTRY

Cardiovascular effects of low versus high-dose beta-carotene in a rat model

(2015) Evelin Csepanyi et al.   PHARMACOLOGICAL RESEARCH

Inflammation, oxidative stress and postoperative atrial fibrillation in cardiac surgery

(2015) M. Zakkar et al.   PHARMACOLOGY & THERAPEUTICS

N-n-butyl haloperidol iodide protects cardiomyocytes against hypoxia/reoxygenation injury by inhibiting autophagy

(2015) Bin Wang et al.   Oncotarget

Inhibition of microRNA-497 ameliorates anoxia/reoxygenation injury in cardiomyocytes by suppressing cell apoptosis and enhancing autophagy

(2015) Xixian Li et al.   Oncotarget

Autophagy and apoptosis: where do they meet?

(2014) Subhadip Mukhopadhyay et al.   APOPTOSIS

Amelioration of human osteoarthritis symptoms with topical ‘biotherapeutics’: a phase I human trial

(2014) Fadia F. Mahmoud et al.   CELL STRESS & CHAPERONES

Histone Deacetylase Inhibition Blunts Ischemia/Reperfusion Injury by Inducing Cardiomyocyte Autophagy

(2014) Min Xie et al.   CIRCULATION

The Relationships Between Cardiovascular Disease and Diabetes

(2014) Jason C. Kovacic et al.   ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA

Sour cherry (Prunus cerasus) seed extract increases heme oxygenase-1 expression and decreases proinflammatory signaling in peripheral blood human leukocytes from rheumatoid arthritis patients

(2014) Fadia Mahmoud et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Autophagy: A potential novel mechanistic contributor to atrial fibrillation

(2014) Yue Yuan et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Cardioprotection Afforded by Sour Cherry Seed Kernel

(2014) Attila Czompa et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Intramyocardial transplantation of cardiac telocytes decreases myocardial infarction and improves post-infarcted cardiac function in rats

(2014) Baoyin Zhao et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Primate energy expenditure and life history

(2014) H. Pontzer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Calcineurin suppresses AMPK-dependent cytoprotective autophagy in cardiomyocytes under oxidative stress

(2014) H He et al.   Cell Death & Disease

Regulation of interplay between autophagy and apoptosis in the diabetic heart

(2013) Ming-Hui Zou et al.   Autophagy

Therapy Against Ischemic Injury

(2013) Giacinta Guarini et al.   CURRENT PHARMACEUTICAL DESIGN

The Cellular Autophagy Markers Beclin-1 and LC3B-II are Increased During Reperfusion in Fibrillated Mouse Hearts

(2013) Gregory Meyer et al.   CURRENT PHARMACEUTICAL DESIGN

Mitochondrial Dynamics: An Emerging Paradigm in Ischemia-Reperfusion Injury

(2013) Lesley Calo et al.   CURRENT PHARMACEUTICAL DESIGN

Diminished Autophagy Limits Cardiac Injury in Mouse Models of Type 1 Diabetes

(2013) Xianmin Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Management of multicellular senescence and oxidative stress

(2013) David D. Haines et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Targeting the unfolded protein response in neurodegeneration: A new approach to therapy

(2013) Mark Halliday et al.   NEUROPHARMACOLOGY

Heme Oxygenase-1 Prevents Cardiac Dysfunction in Streptozotocin-Diabetic Mice by Reducing Inflammation, Oxidative Stress, Apoptosis and Enhancing Autophagy

(2013) Yanli Zhao et al.   PLoS One

Oral Treatment Targeting the Unfolded Protein Response Prevents Neurodegeneration and Clinical Disease in Prion-Infected Mice

(2013) J. A. Moreno et al.   Science Translational Medicine

Autophagosome formation—The role of ULK1 and Beclin1–PI3KC3 complexes in setting the stage

(2013) Martina Wirth et al.   SEMINARS IN CANCER BIOLOGY

Lipid peroxidation end product 4-hydroxy-trans-2-nonenal triggers unfolded protein response and heme oxygenase-1 expression in PC12 cells: Roles of ROS and MAPK pathways

(2013) Meng-Han Lin et al.   TOXICOLOGY

Autophagy activation ameliorates neuronal pathogenesis of FTLD-U mice

(2012) I-Fang Wang et al.   Autophagy

Development of a novel ER stress based selection system for the isolation of highly productive clones

(2012) Lars Kober et al.   BIOTECHNOLOGY AND BIOENGINEERING

Autophagy as a therapeutic target for ischaemia /reperfusion injury? Concepts, controversies, and challenges

(2012) K. Przyklenk et al.   CARDIOVASCULAR RESEARCH

Dissociation of Bcl-2-Beclin1 Complex by Activated AMPK Enhances Cardiac Autophagy and Protects Against Cardiomyocyte Apoptosis in Diabetes

(2012) C. He et al.   DIABETES

Lysosomal pathways to cell death and their therapeutic applications

(2012) Maruša Hafner Česen et al.   EXPERIMENTAL CELL RESEARCH

Differential induction of autophagy in caspase-3/7 down-regulating and Bcl-2 overexpressing recombinant CHO cells subjected to sodium butyrate treatment

(2012) Jae Seong Lee et al.   JOURNAL OF BIOTECHNOLOGY

Ubiquitin-independent function of optineurin in autophagic clearance of protein aggregates

(2012) J. Korac et al.   JOURNAL OF CELL SCIENCE

Cardiac telocytes were decreased during myocardial infarction and their therapeutic effects for ischaemic heart in rat

(2012) Baoyin Zhao et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Recessive mutations in EPG5 cause Vici syndrome, a multisystem disorder with defective autophagy

(2012) Thomas Cullup et al.   NATURE GENETICS

Sour Cherry Seed Kernel Extract Increases Heme Oxygenase-1 Expression and Decreases Representation of CD3+ TNF-α + and CD3 + IL-8+ Subpopulations in Peripheral Blood Leukocyte Cultures from Type 2 Diabetes Patients

(2012) Fadia F. Mahmoud et al.   PHYTOTHERAPY RESEARCH

Myocardial Autophagy after Severe Burn in Rats

(2012) Rong Xiao et al.   PLoS One

Autophagy activators rescue and alleviate pathogenesis of a mouse model with proteinopathies of the TAR DNA-binding protein 43

(2012) I.-F. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of haeme oxygenase-1 in resolution of oxidative stress-related pathologies: focus on cardiovascular, lung, neurological and kidney disorders

(2011) D. D. Haines et al.   Acta Physiologica

The Role of Atg Proteins in Autophagosome Formation

(2011) Noboru Mizushima et al.   Annual Review of Cell and Developmental Biology

Selective autophagy mediated by autophagic adapter proteins

(2011) Terje Johansen et al.   Autophagy

New roles for mitochondria in cell death in the reperfused myocardium

(2011) S.-B. Ong et al.   CARDIOVASCULAR RESEARCH

Human Ventricular Fibrillation During Global Ischemia and Reperfusion

(2011) Chris P. Bradley et al.   Circulation-Arrhythmia and Electrophysiology

Therapeutic hypothermia: Benefits, mechanisms and potential clinical applications in neurological, cardiac and kidney injury

(2011) Elizabeth M. Moore et al.   INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED

p53-TIGAR axis attenuates mitophagy to exacerbate cardiac damage after ischemia

(2011) Atsushi Hoshino et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Impaired cardiac autophagy in patients developing postoperative atrial fibrillation

(2011) Lorena Garcia et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders

(2011) Darren J. Baker et al.   NATURE

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

(2011) Joungmok Kim et al.   NATURE CELL BIOLOGY

Autophagosome targeting and membrane curvature sensing by Barkor/Atg14(L)

(2011) W. Fan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crosstalk between apoptosis and autophagy within the Beclin 1 interactome

(2010) Maria Chiara Maiuri et al.   EMBO JOURNAL

Autophagy as a mechanism for myolysis of cardiomyocytes in mitral regurgitation

(2010) Mien-Cheng Chen et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Review: Autophagy: Definition, Molecular Machinery, and Potential Role in Myocardial Ischemia-Reperfusion Injury

(2010) Yi Dong et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS

Prognosis among survivors of primary ventricular fibrillation in the percutaneous coronary intervention era

(2009) Jonas S.S.G. de Jong et al.   AMERICAN HEART JOURNAL

BAG-1 induces autophagy for cardiac cell survival

(2009) Narasimman Gurusamy et al.   Autophagy

Autophagy is required for preconditioning by the adenosine A1 receptor-selective agonist CCPA

(2009) Smadar Yitzhaki et al.   BASIC RESEARCH IN CARDIOLOGY

Cardioprotection by resveratrol: a novel mechanism via autophagy involving the mTORC2 pathway

(2009) Narasimman Gurusamy et al.   CARDIOVASCULAR RESEARCH

Clinical Outcome and Phenotypic Expression in LAMP2 Cardiomyopathy

(2009) Barry J. Maron   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Cardiac-specific Deletion of LKB1 Leads to Hypertrophy and Dysfunction

(2009) Yasumasa Ikeda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ULK1·ATG13·FIP200 Complex Mediates mTOR Signaling and Is Essential for Autophagy

(2009) Ian G. Ganley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Co-ordinated autophagy with resveratrol and γ-tocotrienol confers synergetic cardioprotection

(2009) Istvan Lekli et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Cardiac anti-remodelling effect of aerobic training is associated with a reduction in the calcineurin/NFAT signalling pathway in heart failure mice

(2009) R. S. F. Oliveira et al.   JOURNAL OF PHYSIOLOGY-LONDON

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL

Cardioprotection by adaptation to ischaemia augments autophagy in association with BAG-1 protein

(2008) Narasimman Gurusamy et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

The Chaperone-Mediated Autophagy Receptor Organizes in Dynamic Protein Complexes at the Lysosomal Membrane

(2008) U. Bandyopadhyay et al.   MOLECULAR AND CELLULAR BIOLOGY