BLOC-1 and BLOC-3 regulate VAMP7 cycling to and from melanosomes via distinct tubular transport carriers

BLOC-1 Brings Together the Actin and Microtubule Cytoskeletons to Generate Recycling Endosomes

(2016) Cédric Delevoye et al.   CURRENT BIOLOGY

BORC, a Multisubunit Complex that Regulates Lysosome Positioning

(2015) Jing Pu et al.   DEVELOPMENTAL CELL

BLOC-2 targets recycling endosomal tubules to melanosomes for cargo delivery

(2015) Megan K. Dennis et al.   JOURNAL OF CELL BIOLOGY

STX13 regulates cargo delivery from recycling endosomes during melanosome biogenesis

(2015) R. A. Jani et al.   JOURNAL OF CELL SCIENCE

VARP Is Recruited on to Endosomes by Direct Interaction with Retromer, Where Together They Function in Export to the Cell Surface

(2014) Geoffrey G. Hesketh et al.   DEVELOPMENTAL CELL

Myosin Vc Interacts with Rab32 and Rab38 Proteins and Works in the Biogenesis and Secretion of Melanosomes

(2014) Jarred J. Bultema et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of molecular heterogeneity in SNX27-retromer-mediated endosome-to-plasma-membrane recycling

(2014) I. J. McGough et al.   JOURNAL OF CELL SCIENCE

Case of Hermansky-Pudlak syndrome 1 patient with milder symptoms in Japanese

(2014) Seiji Takeuchi et al.   JOURNAL OF DERMATOLOGY

Lysosome-related organelles: unusual compartments become mainstream

(2013) Michael S Marks et al.   CURRENT OPINION IN CELL BIOLOGY

Secretory Protein Biogenesis and Traffic in the Early Secretory Pathway

(2013) C. K. Barlowe et al.   GENETICS

Syntaxin-3 Is Required for Melanosomal Localization of Tyrp1 in Melanocytes

(2013) Ayaka Yatsu et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The WASH complex, an endosomal Arp2/3 activator, interacts with the Hermansky–Pudlak syndrome complex BLOC-1 and its cargo phosphatidylinositol-4-kinase type IIα

(2013) P. V. Ryder et al.   MOLECULAR BIOLOGY OF THE CELL

Hermansky-Pudlak Syndrome: Health Care Throughout Life

(2013) S. L. Seward et al.   PEDIATRICS

ATP is released from autophagic vesicles to the extracellular space in a VAMP7-dependent manner

(2012) Claudio Marcelo Fader et al.   Autophagy

SLC35D3 delivery from megakaryocyte early endosomes is required for platelet dense granule biogenesis and is differentially defective in Hermansky-Pudlak syndrome models

(2012) R. Meng et al.   BLOOD

BLOC-3 Mutated in Hermansky-Pudlak Syndrome Is a Rab32/38 Guanine Nucleotide Exchange Factor

(2012) Andreas Gerondopoulos et al.   CURRENT BIOLOGY

Structural Basis of the Intracellular Sorting of the SNARE VAMP7 by the AP3 Adaptor Complex

(2012) Helen M. Kent et al.   DEVELOPMENTAL CELL

A Molecular Network for the Transport of the TI-VAMP/VAMP7 Vesicles from Cell Center to Periphery

(2012) Andrea Burgo et al.   DEVELOPMENTAL CELL

BLOC-2, AP-3, and AP-1 Proteins Function in Concert with Rab38 and Rab32 Proteins to Mediate Protein Trafficking to Lysosome-related Organelles

(2012) Jarred J. Bultema et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Absence of TI-VAMP/Vamp7 Leads to Increased Anxiety in Mice

(2012) L. Danglot et al.   JOURNAL OF NEUROSCIENCE

Differential recognition of a dileucine-based sorting signal by AP-1 and AP-3 reveals a requirement for both BLOC-1 and AP-3 in delivery of OCA2 to melanosomes

(2012) Anand Sitaram et al.   MOLECULAR BIOLOGY OF THE CELL

The binding of Varp to VAMP7 traps VAMP7 in a closed, fusogenically inactive conformation

(2012) Ingmar B Schäfer et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Mechanisms of Protein Delivery to Melanosomes in Pigment Cells

(2012) Anand Sitaram et al.   PHYSIOLOGY

Hermansky-Pudlak syndrome: pigmentary and non-pigmentary defects and their pathogenesis

(2012) Ai-Hua Wei et al.   Pigment Cell & Melanoma Research

RETRACTED: A BLOC-1 Mutation Screen Reveals that PLDN Is Mutated in Hermansky-Pudlak Syndrome Type 9

(2011) Andrew R. Cullinane et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Endosome–lysosome fusion: Figure 1

(2010) J. Paul Luzio et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Docking and Fast Fusion of Synaptobrevin Vesicles Depends on the Lipid Compositions of the Vesicle and the Acceptor SNARE Complex-Containing Target Membrane

(2010) Marta K. Domanska et al.   BIOPHYSICAL JOURNAL

Structure-Function Analysis of VPS9-Ankyrin-repeat Protein (Varp) in the Trafficking of Tyrosinase-related Protein 1 in Melanocytes

(2010) Kanako Tamura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of TI-VAMP and CD82 in EGFR cell-surface dynamics and signaling

(2010) L. Danglot et al.   JOURNAL OF CELL SCIENCE

Neurite outgrowth defects in hippocampal neurons from mice lacking biogenesis of lysosome-related organelles complex-1 (BLOC-1)

(2010) C A Ghiani et al.   MOLECULAR PSYCHIATRY

Fast Vesicle Fusion in Living Cells Requires at Least Three SNARE Complexes

(2010) R. Mohrmann et al.   SCIENCE

Altered lung surfactant system in a Rab38-deficient rat model of Hermansky-Pudlak syndrome

(2009) Kazuhiro Osanai et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

TI-VAMP/VAMP7 and VAMP3/cellubrevin: two v-SNARE proteins involved in specific steps of the autophagy/multivesicular body pathways

(2009) Claudio Marcelo Fader et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The Retromer Coat Complex Coordinates Endosomal Sorting and Dynein-Mediated Transport, with Carrier Recognition by the trans-Golgi Network

(2009) Thomas Wassmer et al.   DEVELOPMENTAL CELL

Coiled-coil interactions are required for post-Golgi R-SNARE trafficking

(2009) David E Gordon et al.   EMBO REPORTS

Role of Varp, a Rab21 exchange factor and TI-VAMP/VAMP7 partner, in neurite growth

(2009) Andrea Burgo et al.   EMBO REPORTS

AP-1 and KIF13A coordinate endosomal sorting and positioning during melanosome biogenesis

(2009) Cédric Delevoye et al.   JOURNAL OF CELL BIOLOGY

Roles of BLOC-1 and Adaptor Protein-3 Complexes in Cargo Sorting to Synaptic Vesicles

(2009) Karen Newell-Litwa et al.   MOLECULAR BIOLOGY OF THE CELL

Varp Is a Novel Rab32/38-binding Protein That Regulates Tyrp1 Trafficking in Melanocytes

(2009) Kanako Tamura et al.   MOLECULAR BIOLOGY OF THE CELL

Varp interacts with Rab38 and functions as its potential effector

(2008) Fang Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Molecular Basis for the Sorting of the SNARE VAMP7 into Endocytic Clathrin-Coated Vesicles by the ArfGAP Hrb

(2008) Paul R. Pryor et al.   CELL

Cell-specific ATP7A transport sustains copper-dependent tyrosinase activity in melanosomes

(2008) Subba Rao Gangi Setty et al.   NATURE