标题
INGs are potential drug targets for cancer
作者
关键词
INGs, Tumor suppressors, Cancer therapy, Cell signaling
出版物
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
Volume 143, Issue 2, Pages 189-197
出版商
Springer Nature
发表日期
2016-08-20
DOI
10.1007/s00432-016-2219-z
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- ING3 protein expression profiling in normal human tissues suggest its role in cellular growth and self-renewal
- (2015) Arash Nabbi et al. EUROPEAN JOURNAL OF CELL BIOLOGY
- ING1b negatively regulates HIF1α protein levels in adipose-derived stromal cells by a SUMOylation-dependent mechanism
- (2015) N Bigot et al. Cell Death & Disease
- ING5 suppresses proliferation, apoptosis, migration and invasion, and induces autophagy and differentiation of gastric cancer cells: a good marker for carcinogenesis and subsequent progression
- (2015) Wen-feng Gou et al. Oncotarget
- The miR-193a-3p-regulated ING5 gene activates the DNA damage response pathway and inhibits multi-chemoresistance in bladder cancer
- (2015) Yang Li et al. Oncotarget
- ING5 inhibits cancer aggressiveness via preventing EMT and is a potential prognostic biomarker for lung cancer
- (2015) Feng Zhang et al. Oncotarget
- Reduced ING1 levels in breast cancer promotes metastasis
- (2015) Satbir Thakur et al. Oncotarget
- Tumor cell apoptosis mediated by cytoplasmic ING1 is associated with improved survival in oral squamous cell carcinoma patients.
- (2015) Pinaki Bose et al. Oncotarget
- Transient Induction of ING4 by Myc Drives Prostate Epithelial Cell Differentiation and Its Disruption Drives Prostate Tumorigenesis
- (2014) P. L. Berger et al. CANCER RESEARCH
- Tumor suppressor Ing1b facilitates DNA repair and prevents oxidative stress induced cell death
- (2013) Anand Rotte et al. APOPTOSIS
- ING1b-inducible microRNA203 inhibits cell proliferation
- (2013) J Chen et al. BRITISH JOURNAL OF CANCER
- ING5 Is a Tip60 Cofactor That Acetylates p53 in Response to DNA Damage
- (2013) N. Liu et al. CANCER RESEARCH
- ING4 inhibits the translation of proto-oncogene MYC by interacting with AUF1
- (2013) Meiling Lu et al. FEBS LETTERS
- Ing1 functions in DNA demethylation by directing Gadd45a to H3K4me3
- (2013) A. Schafer et al. GENES & DEVELOPMENT
- Inhibitor of growth 1 (ING1) acts at early steps of multiple DNA repair pathways
- (2013) Julieta M. Ceruti et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Tumor suppressor ING4 overexpression contributes to proliferation and invasion inhibition in gastric carcinoma by suppressing the NF-κB signaling pathway
- (2013) Shijie Li et al. MOLECULAR BIOLOGY REPORTS
- Inhibitor of growth 4 induces NFκB/p65 ubiquitin-dependent degradation
- (2013) Y Hou et al. ONCOGENE
- ING4 regulates a secretory phenotype in primary fibroblasts with dual effects on cell proliferation and tumor growth
- (2013) A Moreno et al. ONCOGENE
- Src Regulates the Activity of the ING1 Tumor Suppressor
- (2013) Lisa Yu et al. PLoS One
- MicroRNA-650 Was a Prognostic Factor in Human Lung Adenocarcinoma and Confers the Docetaxel Chemoresistance of Lung Adenocarcinoma Cells via Regulating Bcl-2/Bax Expression
- (2013) Jia-Yuan Huang et al. PLoS One
- ING3 Is Essential for Asymmetric Cell Division during Mouse Oocyte Maturation
- (2013) Shinnosuke Suzuki et al. PLoS One
- The ING4 Binding with p53 and Induced p53 Acetylation were Attenuated by Human Papillomavirus 16 E6
- (2013) Yi Guo et al. PLoS One
- Truncation of inhibitor of growth family protein 5 effectively induces senescence, but not apoptosis in human tongue squamous cell carcinoma cell line
- (2013) Lin Qi et al. TUMOR BIOLOGY
- ING1 induces apoptosis through direct effects at the mitochondria
- (2013) P Bose et al. Cell Death & Disease
- Nuclear phosphatidylinositol-5-phosphate regulates ING2 stability at discrete chromatin targets in response to DNA damage
- (2013) Dennis J. Bua et al. Scientific Reports
- The ING1a Tumor Suppressor Regulates Endocytosis to Induce Cellular Senescence Via the Rb-E2F Pathway
- (2013) Uma Karthika Rajarajacholan et al. PLOS BIOLOGY
- Radiosensitivity by ING4–IL-24 bicistronic adenovirus-mediated gene cotransfer on human breast cancer cells
- (2012) Y Zhao et al. CANCER GENE THERAPY
- Expression of inhibitor of growth 4 by HSV1716 improves oncolytic potency and enhances efficacy
- (2012) J Conner et al. CANCER GENE THERAPY
- Enhanced radiosensitivity of non-small-cell lung cancer (NSCLC) by adenovirus-mediated ING4 gene therapy
- (2012) C Ling et al. CANCER GENE THERAPY
- Expression of tumor suppressor gene ING4 in ovarian carcinoma is correlated with microvessel density
- (2012) Yinglan Liu et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- ING1 and 5-Azacytidine Act Synergistically to Block Breast Cancer Cell Growth
- (2012) Satbir Thakur et al. PLoS One
- Negative Regulation of NF-κB by the ING4 Tumor Suppressor in Breast Cancer
- (2012) Sara A. Byron et al. PLoS One
- ING4 is negatively correlated with microvessel density in colon cancer
- (2012) Chun Lou et al. TUMOR BIOLOGY
- Nucleolar protein CSIG is required for p33ING1 function in UV-induced apoptosis
- (2012) N Li et al. Cell Death & Disease
- The tumor suppressor p33ING1bupregulates p16INK4aexpression and induces cellular senescence
- (2011) Na Li et al. FEBS LETTERS
- Citrullination of Inhibitor of Growth 4 (ING4) by Peptidylarginine Deminase 4 (PAD4) Disrupts the Interaction between ING4 and p53
- (2011) Qin Guo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The p53 Tumor Suppressor Is Stabilized by Inhibitor of Growth 1 (ING1) by Blocking Polyubiquitination
- (2011) Subhash Thalappilly et al. PLoS One
- The Inhibitor of Growth Protein 5 (ING5) Depends on INCA1 as a Co-Factor for Its Antiproliferative Effects
- (2011) Feng Zhang et al. PLoS One
- MicroRNA-650 targets ING4 to promote gastric cancer tumorigenicity
- (2010) XueLi Zhang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Regulation of the MicroRNA Processor DGCR8 by the Tumor Suppressor ING1
- (2010) D. Gomez-Cabello et al. CANCER RESEARCH
- A Dominant Mutant Allele of theING4Tumor Suppressor Found in Human Cancer Cells ExacerbatesMYC-Initiated Mouse Mammary Tumorigenesis
- (2010) Suwon Kim et al. CANCER RESEARCH
- Cell Cycle Regulator ING4 Is a Suppressor of Melanoma Angiogenesis That Is Regulated by the Metastasis Suppressor BRMS1
- (2010) J. Li et al. CANCER RESEARCH
- ING2 controls the G1to S-phase transition by regulating p21 expression
- (2010) Delphine Larrieu et al. CELL CYCLE
- Deacetylase Inhibitors Dissociate the Histone-Targeting ING2 Subunit from the Sin3 Complex
- (2010) Karen T. Smith et al. CHEMISTRY & BIOLOGY
- HECT ubiquitin ligase Smurf1 targets the tumor suppressor ING2 for ubiquitination and degradation
- (2010) Jing Nie et al. FEBS LETTERS
- Down-regulation of ING4 is associated with initiation and progression of lung cancer
- (2010) Qiu-shi Wang et al. HISTOPATHOLOGY
- The nuclear to cytoplasmic shift of ING5 protein during colorectal carcinogenesis with their distinct links to pathologic behaviors of carcinomas☆
- (2010) Hua-chuan Zheng et al. HUMAN PATHOLOGY
- Tumor-specific mutation and downregulation of ING5 detected in oral squamous cell carcinoma
- (2010) Beyhan Cengiz et al. INTERNATIONAL JOURNAL OF CANCER
- Decreased nuclear expression and increased cytoplasmic expression of ING5 may be linked to tumorigenesis and progression in human head and neck squamous cell carcinoma
- (2010) Xiaohan Li et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- EBNA3C Attenuates the Function of p53 through Interaction with Inhibitor of Growth Family Proteins 4 and 5
- (2010) A. Saha et al. JOURNAL OF VIROLOGY
- Sumoylation of ING2 regulates the transcription mediated by Sin3A
- (2010) D Ythier et al. ONCOGENE
- The Inhibitor of Growth 1 (ING1) Is Involved in Trichostatin A-Induced Apoptosis and Caspase 3 Signaling in p53-Deficient Glioblastoma Cells
- (2010) Mona Tamannai et al. ONCOLOGY RESEARCH
- Targeted Disruption of Ing2 Results in Defective Spermatogenesis and Development of Soft-Tissue Sarcomas
- (2010) Motonobu Saito et al. PLoS One
- Inhibitor of growth-4 promotes I B promoter activation to suppress NF- B signaling and innate immunity
- (2010) A. H. Coles et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- ING function in apoptosis in diverse model systemsThis paper is one of a selection of papers published in this Special Issue, entitled CSBMCB’s 51st Annual Meeting – Epigenetics and Chromatin Dynamics, and has undergone the Journal’s usual peer review process.
- (2009) Sitar Shah et al. Biochemistry and Cell Biology
- Loss of Inhibitor of Growth (ING-4) is Implicated in the Pathogenesis and Progression of Human Astrocytomas
- (2009) George Klironomos et al. BRAIN PATHOLOGY
- Decreased Expression of Inhibitor of Growth 4 Correlated with Poor Prognosis of Hepatocellular Carcinoma
- (2009) F. Fang et al. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
- ING2 is upregulated in colon cancer and increases invasion by enhanced MMP13 expression
- (2009) Kensuke Kumamoto et al. INTERNATIONAL JOURNAL OF CANCER
- Expression of candidate tumor suppressor gene ING2 is lost in non-small cell lung carcinoma
- (2009) Damien Ythier et al. LUNG CANCER
- ING4 Mediates Crosstalk between Histone H3 K4 Trimethylation and H3 Acetylation to Attenuate Cellular Transformation
- (2009) Tiffany Hung et al. MOLECULAR CELL
- The tumor suppressor ING3 is degraded by SCFSkp2-mediated ubiquitin–proteasome system
- (2009) G Chen et al. ONCOGENE
- The Inhibitor of Growth 1 (ING1) Proteins Suppress Angiogenesis and Differentially Regulate Angiopoietin Expression in Glioblastoma Cells
- (2009) Gesche Tallen et al. ONCOLOGY RESEARCH
- ING1 protein targeting to the nucleus by karyopherins is necessary for activation of p21
- (2008) Michael W. Russell et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- ING2 recruits histone methyltransferase activity with methylation site specificity distinct from histone H3 lysines 4 and 9
- (2008) Frauke Goeman et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Nutlin-3a Activates p53 to Both Down-regulate Inhibitor of Growth 2 and Up-regulate mir-34a, mir-34b, and mir-34c Expression, and Induce Senescence
- (2008) K. Kumamoto et al. CANCER RESEARCH
- p37Ing1bRegulates B-Cell Proliferation and Cooperates with p53 to Suppress Diffuse Large B-Cell Lymphomagenesis
- (2008) Andrew H. Coles et al. CANCER RESEARCH
- Downregulation of ING3 mRNA expression predicts poor prognosis in head and neck cancer
- (2008) Mehmet Gunduz et al. CANCER SCIENCE
- NAD(P)H quinone oxidoreductase 1 inhibits the proteasomal degradation of the tumour suppressor p33ING1b
- (2008) Marco Garate et al. EMBO REPORTS
- The Caenorhabditis elegans ing-3 Gene Regulates Ionizing Radiation-Induced Germ-Cell Apoptosis in a p53-Associated Pathway
- (2008) J. Luo et al. GENETICS
- Human inhibitor of growth 1 inhibits hepatoma cell growth and influences p53 stability in a variant-dependent manner
- (2008) Zhi Zhu et al. HEPATOLOGY
- ING2 as a Novel Mediator of Transforming Growth Factor-β-dependent Responses in Epithelial Cells
- (2008) Krishna P. Sarker et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Molecular Basis of Histone H3K4me3 Recognition by ING4
- (2008) Alicia Palacios et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Frequent deletion of ING2 locus at 4q35.1 associates with advanced tumor stage in head and neck squamous cell carcinoma
- (2008) Silvia S. Borkosky et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- Histone H3K4me3 Binding Is Required for the DNA Repair and Apoptotic Activities of ING1 Tumor Suppressor
- (2008) P.V. Peña et al. JOURNAL OF MOLECULAR BIOLOGY
- The ING4 Tumor Suppressor Attenuates NF- B Activity at the Promoters of Target Genes
- (2008) S. Nozell et al. MOLECULAR AND CELLULAR BIOLOGY
- Tethering by lamin A stabilizes and targets the ING1 tumour suppressor
- (2008) Xijing Han et al. NATURE CELL BIOLOGY
- The crystal structure of the ING5 PHD finger in complex with an H3K4me3 histone peptide
- (2008) Karen S. Champagne et al. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
- Decreased expression of ING2 gene and its clinicopathological significance in hepatocellular carcinoma
- (2007) Hua-kun Zhang et al. CANCER LETTERS
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now