Lactate Induces the Expressions of MCT1 and HCAR1 to Promote Tumor Growth and Progression in Glioblastoma

The Crosstalk between GPR81/IGFBP6 Promotes Breast Cancer Progression by Modulating Lactate Metabolism and Oxidative Stress

(2022) Lucia Longhitano et al.   Antioxidants

Diagnostic Utility of the Immunohistochemical Expression of Serin and Arginine Rich Splicing Factor 1 (SRSF1) in the Differential Diagnosis of Adult Gliomas

(2021) Giuseppe Broggi et al.   Cancers

Brain CHID1 Expression Correlates with NRGN and CALB1 in Healthy Subjects and AD Patients

(2021) Paola Castrogiovanni et al.   Cells

Transport function, regulation, and biology of human monocarboxylate transporter 1 (hMCT1) and 4 (hMCT4)

(2021) Masaki Kobayashi et al.   PHARMACOLOGY & THERAPEUTICS

IDH mutation in glioma: molecular mechanisms and potential therapeutic targets

(2020) Sue Han et al.   BRITISH JOURNAL OF CANCER

Changes in the Expression of Pre-Replicative Complex Genes in hTERT and ALT Pediatric Brain Tumors

(2020) Aurora Irene Idilli et al.   Cancers

The expression levels of CHI3L1 and IL15Rα correlate with TGM2 in duodenum biopsies of patients with celiac disease

(2020) Paola Catrogiovanni et al.   INFLAMMATION RESEARCH

SRC Tyrosine Kinase Inhibitor and X-rays Combined Effect on Glioblastoma Cell Lines

(2020) Filippo Torrisi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Role of Proton-Coupled Monocarboxylate Transporters in Cancer: From Metabolic Crosstalk to Therapeutic Potential

(2020) Xiangyu Sun et al.   Frontiers in Cell and Developmental Biology

The Role of Hypoxia and SRC Tyrosine Kinase in Glioblastoma Invasiveness and Radioresistance

(2020) Filippo Torrisi et al.   Cancers

HCAR1/MCT1 Regulates Tumor Ferroptosis through the Lactate-Mediated AMPK-SCD1 Activity and Its Therapeutic Implications

(2020) Youbo Zhao et al.   Cell Reports

Glioblastoma Stem-Like Cells, Metabolic Strategy to Kill a Challenging Target

(2019) Delphine Garnier et al.   Frontiers in Oncology

Inflammation and Metabolism in Cancer Cell—Mitochondria Key Player

(2019) Monica Neagu et al.   Frontiers in Oncology

SOX4: Epigenetic regulation and role in tumorigenesis

(2019) Hamza Hanieh et al.   SEMINARS IN CANCER BIOLOGY

Lactate-mediated epigenetic reprogramming regulates formation of human pancreatic cancer-associated fibroblasts

(2019) Tushar D Bhagat et al.   eLife

Lactate/GPR81 signaling and proton motive force in cancer: Role in angiogenesis, immune escape, nutrition, and Warburg phenomenon

(2019) Timothy P. Brown et al.   PHARMACOLOGY & THERAPEUTICS

Neurofilaments in blood is a new promising preclinical biomarker for the screening of natural scrapie in sheep

(2019) Henrik Zetterberg et al.   PLoS One

Expression of Bcl-2 is a favorable prognostic biomarker in lung squamous cell carcinoma

(2018) Changjiang Feng et al.   Oncology Letters

The REMBRANDT study, a large collection of genomic data from brain cancer patients

(2018) Yuriy Gusev et al.   Scientific Data

Feature selection and tumor classification for microarray data using relaxed Lasso and generalized multi-class support vector machine

(2018) Chuanze Kang et al.   JOURNAL OF THEORETICAL BIOLOGY

Monocarboxylate transporter 1 is a key player in glioma-endothelial cell crosstalk

(2017) Vera Miranda-Gonçalves et al.   MOLECULAR CARCINOGENESIS

Clustering by fast search and merge of local density peaks for gene expression microarray data

(2017) Rashid Mehmood et al.   Scientific Reports

A novel brain tumour model in zebrafish reveals the role of YAP activation in MAPK- and PI3K-induced malignant growth

(2016) Marie Mayrhofer et al.   Disease Models & Mechanisms

The Warburg Effect: How Does it Benefit Cancer Cells?

(2016) Maria V. Liberti et al.   TRENDS IN BIOCHEMICAL SCIENCES

Mutant IDH1 expression is associated with down-regulation of monocarboxylate transporters

(2016) Pavithra Viswanath et al.   Oncotarget

Heme oxygenase-1 nuclear translocation regulates bortezomib-induced cytotoxicity and mediates genomic instability in myeloma cells

(2016) Daniele Tibullo et al.   Oncotarget

G-protein-coupled receptor 81 promotes a malignant phenotype in breast cancer through angiogenic factor secretion

(2016) Yu Jin Lee et al.   Oncotarget

Cell Surface Lactate Receptor GPR81 Is Crucial for Cancer Cell Survival

(2014) C. L. Roland et al.   CANCER RESEARCH

Lactate Reduces Liver and Pancreatic Injury in Toll-Like Receptor– and Inflammasome-Mediated Inflammation via GPR81-Mediated Suppression of Innate Immunity

(2014) Rafaz Hoque et al.   GASTROENTEROLOGY

YuGene: A simple approach to scale gene expression data derived from different platforms for integrated analyses

(2014) Kim-Anh Lê Cao et al.   GENOMICS

Fatty Acid Synthase Mediates the Epithelial-Mesenchymal Transition of Breast Cancer Cells

(2014) Junqin Li et al.   International Journal of Biological Sciences

PGC-1α mediates mitochondrial biogenesis and oxidative phosphorylation in cancer cells to promote metastasis

(2014) Valerie S. LeBleu et al.   NATURE CELL BIOLOGY

Metabolic reprogramming during TGFβ1-induced epithelial-to-mesenchymal transition

(2014) L Jiang et al.   ONCOGENE

A Microarray Platform-Independent Classification Tool for Cell of Origin Class Allows Comparative Analysis of Gene Expression in Diffuse Large B-cell Lymphoma

(2013) Matthew A. Care et al.   PLoS One

Coffee enhances the expression of chaperones and antioxidant proteins in rats with nonalcoholic fatty liver disease

(2013) Federico Salomone et al.   Translational Research

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Lactate is a mediator of metabolic cooperation between stromal carcinoma associated fibroblasts and glycolytic tumor cells in the tumor microenvironment

(2011) Yanique I. Rattigan et al.   EXPERIMENTAL CELL RESEARCH

The perivascular niche microenvironment in brain tumor progression

(2010) Nikki A Charles et al.   CELL CYCLE

An Autocrine Lactate Loop Mediates Insulin-Dependent Inhibition of Lipolysis through GPR81

(2010) Kashan Ahmed et al.   Cell Metabolism

Increased 18F-FDG uptake and expression of Glut1 in the EMT transformed breast cancer cells induced by TGF-β

(2010) W. Li et al.   NEOPLASMA

Kita Driven Expression of Oncogenic HRAS Leads to Early Onset and Highly Penetrant Melanoma in Zebrafish

(2010) Cristina Santoriello et al.   PLoS One

Tumor metabolism of lactate: the influence and therapeutic potential for MCT and CD147 regulation

(2009) Kelly M Kennedy et al.   Future Oncology

Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial

(2009) Roger Stupp et al.   LANCET ONCOLOGY

Can Survival Prediction Be Improved By Merging Gene Expression Data Sets?

(2009) Haleh Yasrebi et al.   PLoS One

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

An integrated cross-platform prognosis study on neuroblastoma patients

(2008) Qing-Rong Chen et al.   GENOMICS

TB database: an integrated platform for tuberculosis research

(2008) T. B. K. Reddy et al.   NUCLEIC ACIDS RESEARCH