Macrophage Migration Inhibitory Factor (MIF) Supports Homing of Osteoclast Precursors to Peripheral Osteolytic Lesions

Macrophage migration inhibitory factor is essential for osteoclastogenic mechanisms in vitro and in vivo mouse model of arthritis

(2015) Ran Gu et al.   CYTOKINE

AMD3100 improves ovariectomy-induced osteoporosis in mice by facilitating mobilization of hematopoietic stem/progenitor cells

(2014) Jin Young Im et al.   BMB Reports

Metallic wear debris may regulate CXCR4 expressionin vitroandin vivo

(2014) Andreas Drynda et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

MIF Promotes B Cell Chemotaxis through the Receptors CXCR4 and CD74 and ZAP-70 Signaling

(2014) C. Klasen et al.   JOURNAL OF IMMUNOLOGY

High-mobility group box-1 in sterile inflammation

(2014) A. Tsung et al.   JOURNAL OF INTERNAL MEDICINE

MIF, a potential therapeutic target for rheumatoid arthritis?

(2014) Zhaolin Chen et al.   RHEUMATOLOGY INTERNATIONAL

Human Anti-Macrophage Migration Inhibitory Factor Antibodies Inhibit Growth of Human Prostate Cancer Cells In Vitro and In Vivo

(2013) F. Hussain et al.   MOLECULAR CANCER THERAPEUTICS

Macrophage-derived, macrophage migration inhibitory factor (MIF) is necessary to induce disease in the K/BxN serum-induced model of arthritis

(2013) Anjana Singh et al.   RHEUMATOLOGY INTERNATIONAL

Particle disease: Biologic mechanisms of periprosthetic osteolysis in total hip arthroplasty

(2012) Jiri Gallo et al.   Innate Immunity

Deletion of CD74, a putative MIF receptor, in mice enhances osteoclastogenesis and decreases bone mass

(2012) Se Hwan Mun et al.   JOURNAL OF BONE AND MINERAL RESEARCH

HMGB1 promotes recruitment of inflammatory cells to damaged tissues by forming a complex with CXCL12 and signaling via CXCR4

(2012) Milena Schiraldi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Systemic Circulation and Bone Recruitment of Osteoclast Precursors Tracked by Using Fluorescent Imaging Techniques

(2012) M. Kotani et al.   JOURNAL OF IMMUNOLOGY

Lineage-committed osteoclast precursors circulate in blood and settle down into bone

(2011) Akinori Muto et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Macrophage Migration Inhibitory Factor and CD74 Regulate Macrophage Chemotactic Responses via MAPK and Rho GTPase

(2011) H. Fan et al.   JOURNAL OF IMMUNOLOGY

Selective inhibition of the MCP-1-CCR2 ligand-receptor axis decreases systemic trafficking of macrophages in the presence of UHMWPE particles

(2011) Emmanuel Gibon et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

MIF induces osteoclast differentiation and contributes to progression of periodontal disease in mice

(2011) Mila Fernandes Moreira Madeira et al.   MICROBES AND INFECTION

High-mobility group box 1 and cancer

(2010) Daolin Tang et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Reduced arthritis in MIF deficient mice is associated with reduced T cell activation: down-regulation of ERK MAP kinase phosphorylation

(2010) L. L. Santos et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Chemorepulsion by blood S1P regulates osteoclast precursor mobilization and bone remodeling in vivo

(2010) Masaru Ishii et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Macrophage Migration Inhibitory Factor Increases Leukocyte-Endothelial Interactions in Human Endothelial Cells via Promotion of Expression of Adhesion Molecules

(2010) Q. Cheng et al.   JOURNAL OF IMMUNOLOGY

mAbs

(2010) Pablo A. Scolnik   mAbs

Unknown

(2010) Pei-Fen Chen et al.   MOLECULAR MEDICINE

Macrophage migration inhibitory factor inhibits osteoclastogenesis

(2009) Claire Jacquin et al.   BONE

A functional heteromeric MIF receptor formed by CD74 and CXCR4

(2009) Verena Schwartz et al.   FEBS LETTERS

Role of CX3CL1/Fractalkine in Osteoclast Differentiation and Bone Resorption

(2009) K. Koizumi et al.   JOURNAL OF IMMUNOLOGY

Sphingosine-1-phosphate mobilizes osteoclast precursors and regulates bone homeostasis

(2009) Masaru Ishii et al.   NATURE

The role of Mac-1 (CD11b/CD18) in osteoclast differentiation induced by receptor activator of nuclear factor-κB ligand

(2008) Hidetaka Hayashi et al.   FEBS LETTERS

HMGB1 Regulates RANKL-Induced Osteoclastogenesis in a Manner Dependent on RAGE

(2008) Zheng Zhou et al.   JOURNAL OF BONE AND MINERAL RESEARCH

TNF inhibits production of stromal cell-derived factor 1 by bone stromal cells and increases osteoclast precursor mobilization from bone marrow to peripheral blood

(2008) Qian Zhang et al.   ARTHRITIS RESEARCH & THERAPY