Selective inhibition of the MCP-1-CCR2 ligand-receptor axis decreases systemic trafficking of macrophages in the presence of UHMWPE particles

What experimental approaches (eg, in vivo, in vitro, tissue retrieval) are effective in investigating the biologic effects of particles?

(2016) Mathias Bostrom et al.   JOURNAL OF THE AMERICAN ACADEMY OF ORTHOPAEDIC SURGEONS

What are the local and systemic biologic reactions and mediators to wear debris, and what host factors determine or modulate the biologic response to wear particles?

(2016) Rocky S. Tuan et al.   JOURNAL OF THE AMERICAN ACADEMY OF ORTHOPAEDIC SURGEONS

Cellular chemotaxis induced by wear particles from joint replacements

(2010) Stuart B. Goodman et al.   BIOMATERIALS

Continuous Infusion of UHMWPE Particles Induces Increased Bone Macrophages and Osteolysis

(2010) Pei-Gen Ren et al.   CLINICAL ORTHOPAEDICS AND RELATED RESEARCH

Bone resorption activity of particulate-stimulated macrophages

(2010) Tibor T. Glant et al.   JOURNAL OF BONE AND MINERAL RESEARCH

The Epidemiology of Bearing Surface Usage in Total Hip Arthroplasty in the United States

(2009) Kevin J Bozic et al.   JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME

Monocyte Chemoattractant Protein-1 (MCP-1): An Overview

(2009) Satish L. Deshmane et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Estrogen-dependent and C-C chemokine receptor-2–dependent pathways determine osteoclast behavior in osteoporosis

(2009) Nikolaus B Binder et al.   NATURE MEDICINE

An in vivo murine model of continuous intramedullary infusion of polyethylene particles

(2008) Ting Ma et al.   BIOMATERIALS

Continuous intramedullary polymer particle infusion using a murine femoral explant model

(2008) Steven G. Ortiz et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS

Macrophage depletion diminishes implant-wear-induced inflammatory osteolysis in a mouse model

(2007) Weiping Ren et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Circulating cells with osteogenic potential are physiologically mobilized into the fracture healing site in the parabiotic mice model

(2007) Ken Kumagai et al.   JOURNAL OF ORTHOPAEDIC RESEARCH