Clinical Significance of Serum Albumin and Implications of FcRn Inhibitor Treatment in IgG-Mediated Autoimmune Disorders
出版年份 2022 全文链接
标题
Clinical Significance of Serum Albumin and Implications of FcRn Inhibitor Treatment in IgG-Mediated Autoimmune Disorders
作者
关键词
-
出版物
Frontiers in Immunology
Volume 13, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2022-06-01
DOI
10.3389/fimmu.2022.892534
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of HBM9161, a novel FcRn inhibitor, in a Phase 1 Study for Healthy Chinese Volunteers
- (2021) Desmond Y.H. Yap et al. CTS-Clinical and Translational Science
- Assessment of clinical factors affecting outcome of myasthenia gravis
- (2021) Yukiyo Yoshimoto et al. MUSCLE & NERVE
- Fc-Receptor Targeted Therapies for the Treatment of Myasthenia gravis
- (2021) Christian W. Keller et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Safety, Tolerability, and Activity of ALXN1830 Targeting the Neonatal Fc Receptor in Chronic Pemphigus
- (2021) Victoria P. Werth et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Safety, efficacy, and tolerability of efgartigimod in patients with generalised myasthenia gravis (ADAPT): a multicentre, randomised, placebo-controlled, phase 3 trial
- (2021) James F Howard et al. LANCET NEUROLOGY
- The Effect of Plasma Protein Binding on the Therapeutic Monitoring of Antiseizure Medications
- (2021) Bruno Charlier et al. Pharmaceutics
- Treatment of pemphigus vulgaris and foliaceus with efgartigimod, a neonatal Fc receptor inhibitor: a phase II multicentre, open‐label feasibility trial
- (2021) M. Goebeler et al. BRITISH JOURNAL OF DERMATOLOGY
- IgG regulation through FcRn blocking: A novel mechanism for the treatment of myasthenia gravis
- (2021) Gil I. Wolfe et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- Albumin in decompensated cirrhosis: new concepts and perspectives
- (2020) Mauro Bernardi et al. GUT
- Human Serum Albumin Aggregation/Fibrillation and its Abilities to Drugs Binding
- (2020) Małgorzata Maciążek-Jurczyk et al. MOLECULES
- Albumin and bleed risk in rivaroxaban treated patients
- (2020) E. Wojakowski et al. JOURNAL OF THROMBOSIS AND THROMBOLYSIS
- Serum albumin and cardiovascular disease: State-of-the-art review
- (2020) S. Arques ANNALES DE CARDIOLOGIE ET D ANGEIOLOGIE
- An engineered human albumin enhances half-life and transmucosal delivery when fused to protein-based biologics
- (2020) Malin Bern et al. Science Translational Medicine
- S-Thiolation Targets Albumin in Heart Failure
- (2020) Maura Brioschi et al. Antioxidants
- Phase 2 multiple-dose study of an FcRn inhibitor, rozanolixizumab, in patients with primary immune thrombocytopenia
- (2020) Tadeusz Robak et al. Blood Advances
- Efficacy and safety of rozanolixizumab in moderate-to-severe generalised myasthenia gravis
- (2020) Vera Bril et al. NEUROLOGY
- Structural basis of drug recognition by human serum albumin
- (2019) Loris Leboffe et al. CURRENT MEDICINAL CHEMISTRY
- Neonatal Fc receptor expression in macrophages is indispensable for IgG homeostasis
- (2019) Dilip K. Challa et al. mAbs
- Pro-oxidant and pro-inflammatory effects of glycated albumin on cardiomyocytes
- (2019) Alma Martinez Fernandez et al. FREE RADICAL BIOLOGY AND MEDICINE
- Reduced FcRn-mediated transcytosis of IgG2 due to a missing Glycine in its lower hinge
- (2019) Nigel M. Stapleton et al. Scientific Reports
- The Neonatal Fc Receptor (FcRn): A Misnomer?
- (2019) Michal Pyzik et al. Frontiers in Immunology
- Impaired albumin function: a novel potential indicator for liver function damage?
- (2019) Lejia Sun et al. ANNALS OF MEDICINE
- Myasthenia gravis: Historical achievements and the “golden age” of clinical trials
- (2019) Tam M. Nguyen-Cao et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- Human serum albumin presents isoform variants with altered neonatal Fc receptor interactions
- (2019) Yann Leblanc et al. PROTEIN SCIENCE
- Phase 2 study of efgartigimod, a novel FcRn antagonist, in adult patients with primary immune thrombocytopenia
- (2019) Adrian C. Newland et al. AMERICAN JOURNAL OF HEMATOLOGY
- Blocking FcRn in humans reduces circulating IgG levels and inhibits IgG immune complex–mediated immune responses
- (2019) L. J. Blumberg et al. Science Advances
- New Insights About Albumin and Liver Disease
- (2018) Joana R. Carvalho et al. Annals of Hepatology
- Extending human IgG half-life using structure-guided design
- (2018) Brian J. Booth et al. mAbs
- Harnessing albumin as a carrier for cancer therapies
- (2018) Ella N. Hoogenboezem et al. ADVANCED DRUG DELIVERY REVIEWS
- Crosstalk between zinc and free fatty acids in plasma
- (2018) James P.C. Coverdale et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Neonatal Fc receptor antagonist efgartigimod safely and sustainably reduces IgGs in humans
- (2018) Peter Ulrichts et al. JOURNAL OF CLINICAL INVESTIGATION
- Cellular recycling-driven in vivo half-life extension using recombinant albumin fusions tuned for neonatal Fc receptor (FcRn) engagement
- (2018) Maja Thim Larsen et al. JOURNAL OF CONTROLLED RELEASE
- Generation and characterization of a high affinity anti-human FcRn antibody, rozanolixizumab, and the effects of different molecular formats on the reduction of plasma IgG concentration
- (2018) Bryan Smith et al. mAbs
- M281, an Anti-FcRn Antibody: Pharmacodynamics, Pharmacokinetics, and Safety Across the Full Range of IgG Reduction in a First-in-Human Study
- (2018) Leona E. Ling et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Hypoalbuminemia: Pathogenesis and Clinical Significance
- (2018) Peter B. Soeters et al. JOURNAL OF PARENTERAL AND ENTERAL NUTRITION
- Clinical Implications Associated With the Posttranslational Modification–Induced Functional Impairment of Albumin in Oxidative Stress–Related Diseases
- (2017) Hiroshi Watanabe et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Hepatic FcRn regulates albumin homeostasis and susceptibility to liver injury
- (2017) Michal Pyzik et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The FcRn inhibitor rozanolixizumab reduces human serum IgG concentration: A randomized phase 1 study
- (2017) Peter Kiessling et al. Science Translational Medicine
- Evaluation of Blood Biomarkers Associated with Risk of Malnutrition in Older Adults: A Systematic Review and Meta-Analysis
- (2017) Zhiying Zhang et al. Nutrients
- Association of Albumin Levels With Outcome in Intravenous Immunoglobulin–Treated Guillain-Barré Syndrome
- (2017) Willem-Jan R. Fokkink et al. JAMA Neurology
- Low antioxidant status of serum bilirubin, uric acid, albumin and creatinine in patients with myasthenia gravis
- (2016) Dehao Yang et al. INTERNATIONAL JOURNAL OF NEUROSCIENCE
- Disorders of lipid metabolism in nephrotic syndrome: mechanisms and consequences
- (2016) Nosratola D. Vaziri KIDNEY INTERNATIONAL
- Low serum albumin concentrations are associated with disease severity in patients with myasthenia gravis
- (2016) Yi-Yun Weng et al. MEDICINE
- FcRn: The Architect Behind the Immune and Nonimmune Functions of IgG and Albumin
- (2015) Michal Pyzik et al. JOURNAL OF IMMUNOLOGY
- Albumin-deficient mouse models for studying metabolism of human albumin and pharmacokinetics of albumin-based drugs
- (2015) Derry C Roopenian et al. mAbs
- Charge-mediated influence of the antibody variable domain on FcRn-dependent pharmacokinetics
- (2015) Angela Schoch et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Unraveling the Interaction between FcRn and Albumin: Opportunities for Design of Albumin-Based Therapeutics
- (2015) Kine Marita Knudsen Sand et al. Frontiers in Immunology
- Interactive Association of Drugs Binding to Human Serum Albumin
- (2014) Feng Yang et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Dissection of the Neonatal Fc Receptor (FcRn)-Albumin Interface Using Mutagenesis and Anti-FcRn Albumin-blocking Antibodies
- (2014) Kine Marita Knudsen Sand et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Structural Insights into Neonatal Fc Receptor-based Recycling Mechanisms
- (2014) Vaheh Oganesyan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Human serum albumin, systemic inflammation, and cirrhosis
- (2014) Vicente Arroyo et al. JOURNAL OF HEPATOLOGY
- The Proximal Tubule and Albuminuria: Really!
- (2014) L. E. Dickson et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Nephrotic Syndrome: Components, Connections, and Angiopoietin-Like 4-Related Therapeutics
- (2014) C. Mace et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- The prevalence, characteristics, and clinical significance of abnormal albuminuria in patients with hypertension
- (2014) Shunsuke Murai et al. Scientific Reports
- Unraveling the mysteries of serum albumin—more than just a serum protein
- (2014) Angelica M. Merlot et al. Frontiers in Physiology
- Novel insights into the pleiotropic effects of human serum albumin in health and disease
- (2013) Chung-Eun Ha et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Albumin as a versatile platform for drug half-life extension
- (2013) Darrell Sleep et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Albumin–drug interaction and its clinical implication
- (2013) Keishi Yamasaki et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Review: Glycation of human serum albumin
- (2013) Jeanethe Anguizola et al. CLINICA CHIMICA ACTA
- Increased frequency of microalbuminuria in patients receiving statins
- (2013) Nicolas Roberto Robles et al. Clinical Lipidology
- Serum albumin acts as a shuttle to enhance cholesterol efflux from cells
- (2013) Sandhya Sankaranarayanan et al. JOURNAL OF LIPID RESEARCH
- Albumin Is Recycled from the Primary Urine by Tubular Transcytosis
- (2013) V. Tenten et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Analytical FcRn affinity chromatography for functional characterization of monoclonal antibodies
- (2013) Tilman Schlothauer et al. mAbs
- Multivalent immune complexes divert FcRn to lysosomes by exclusion from recycling sorting tubules
- (2013) Andrew W. Weflen et al. MOLECULAR BIOLOGY OF THE CELL
- Crystal Structure of an HSA/FcRn Complex Reveals Recycling by Competitive Mimicry of HSA Ligands at a pH-Dependent Hydrophobic Interface
- (2013) Michael M. Schmidt et al. STRUCTURE
- Effect of blood protein concentrations on drug-dosing regimes: practical guidance
- (2013) Konstantin G Gurevich Theoretical Biology and Medical Modelling
- Specific antioxidant properties of human serum albumin
- (2013) Myriam Taverna et al. Annals of Intensive Care
- The glycation of albumin: Structural and functional impacts
- (2010) Philippe Rondeau et al. BIOCHIMIE
- Albumin as Fatty Acid Transporter
- (2009) Ger J. van der Vusse Drug Metabolism and Pharmacokinetics
- Renal FcRn Reclaims Albumin but Facilitates Elimination of IgG
- (2009) M. Sarav et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Conditional deletion of the MHC class I-related receptor FcRn reveals the sites of IgG homeostasis in mice
- (2009) Héctor Pérez Montoyo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Dyslipidemia and cardiovascular risk: the importance of early prevention
- (2009) M. Miller QJM-AN INTERNATIONAL JOURNAL OF MEDICINE
- Microalbuminuria in Type 2 Diabetes and Hypertension: A marker, treatment target, or innocent bystander?
- (2008) S. Basi et al. DIABETES CARE
- The antioxidant properties of serum albumin
- (2008) Marjolaine Roche et al. FEBS LETTERS
- Statins may aggravate myasthenia gravis
- (2008) Shin J. Oh et al. MUSCLE & NERVE
- The Interaction Between Cholesterol and Human Serum Albumin
- (2008) Liu Peng et al. PROTEIN AND PEPTIDE LETTERS
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started