M281, an Anti-FcRn Antibody: Pharmacodynamics, Pharmacokinetics, and Safety Across the Full Range of IgG Reduction in a First-in-Human Study

The unmet need in rheumatology: Reports from the targeted therapies meeting 2017

(2018) Kevin L. Winthrop et al.   CLINICAL IMMUNOLOGY

Opportunistic infections in rheumatoid arthritis patients exposed to biologic therapy: results from the British Society for Rheumatology Biologics Register for Rheumatoid Arthritis

(2018) Andrew I Rutherford et al.   RHEUMATOLOGY

A Systematic Review and Pooled Analysis of Select Safety Parameters Among Normal Healthy Volunteers Taking Placebo in Phase 1 Clinical Trials

(2017) Tina C. Young et al.   JOURNAL OF CLINICAL PHARMACOLOGY

The FcRn inhibitor rozanolixizumab reduces human serum IgG concentration: A randomized phase 1 study

(2017) Peter Kiessling et al.   Science Translational Medicine

Analysis of a Compartmental Model of Endogenous Immunoglobulin G Metabolism with Application to Multiple Myeloma

(2017) Felicity Kendrick et al.   Frontiers in Physiology

Approach to asymptomatic creatine kinase elevation

(2016) S. MOGHADAM-KIA et al.   CLEVELAND CLINIC JOURNAL OF MEDICINE

Risk Factors and Clinical Significance of Lymphopenia in Survivors of the Fontan Procedure for Single-Ventricle Congenital Cardiac Disease

(2016) Megan M. Morsheimer et al.   Journal of Allergy and Clinical Immunology-In Practice

Rituximab in refractory myasthenia gravis: a prospective, open-label study with long-term follow-up

(2016) Dustin Anderson et al.   Annals of Clinical and Translational Neurology

The neonatal Fc receptor, FcRn, as a target for drug delivery and therapy

(2015) Jonathan T. Sockolosky et al.   ADVANCED DRUG DELIVERY REVIEWS

Autoantibodies in systemic autoimmune diseases: specificity and pathogenicity

(2015) Jolien Suurmond et al.   JOURNAL OF CLINICAL INVESTIGATION

Fully Human Monoclonal Antibody Inhibitors of the Neonatal Fc Receptor Reduce Circulating IgG in Non-Human Primates

(2015) Andrew E. Nixon et al.   Frontiers in Immunology

Neonatal Fc Receptor Promotes Immune Complex-Mediated Glomerular Disease

(2013) F. Olaru et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The maternal immune response to fetal platelet GPIbα causes frequent miscarriage in mice that can be prevented by intravenous IgG and anti-FcRn therapies

(2011) Conglei Li et al.   JOURNAL OF CLINICAL INVESTIGATION

Neonatal Fc Receptor Blockade by Fc Engineering Ameliorates Arthritis in a Murine Model

(2011) D. A. Patel et al.   JOURNAL OF IMMUNOLOGY

Clinical chemistry of human FcRn transgenic mice

(2011) Carsten Stein et al.   MAMMALIAN GENOME

Lupus nephritis: prolonged immunoadsorption (IAS) reduces proteinuria and stabilizes global disease activity

(2011) G. H. Stummvoll et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Safety and clinical outcomes of rituximab therapy in patients with different autoimmune diseases: experience from a national registry (GRAID)

(2011) Hans-Peter Tony et al.   ARTHRITIS RESEARCH & THERAPY

Animal model of fetal and neonatal immune thrombocytopenia: role of neonatal Fc receptor in the pathogenesis and therapy

(2010) P. Chen et al.   BLOOD

The neonatal Fc receptor as therapeutic target in IgG-mediated autoimmune diseases

(2010) Alina Sesarman et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Autoantibodies in Autoimmune Diseases

(2010) M. Eggert et al.   CURRENT PHARMACEUTICAL DESIGN

Slow responses to standard dose rituximab in immune thrombocytopenic purpura

(2009) K. Kelly et al.   HAEMATOLOGICA

Comparing the Autoantibody Levels and Clinical Efficacy of Double Filtration Plasmapheresis, Immunoadsorption, and Intravenous Immunoglobulin for the Treatment of Late-onset Myasthenia Gravis

(2009) Jun-Feng Liu et al.   THERAPEUTIC APHERESIS AND DIALYSIS

Immunoglobulin Replacement Therapy in Children

(2008) Maria Garcia-Lloret et al.   IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA

The Four Most Common Pediatric Immunodeficiencies

(2008) E. Richard Stiehm   Journal of Immunotoxicology

Muscular exercise can cause highly pathological liver function tests in healthy men

(2007) Jonas Pettersson et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY