NEDD9 sustains hexokinase expression to promote glycolysis

Nedd9 restrains autophagy to limit growth of early stage non-small cell lung cancer

(2021) Alexander Y Deneka et al.   CANCER RESEARCH

PTEN Suppresses Glycolysis by Dephosphorylating and Inhibiting Autophosphorylated PGK1

(2019) Xu Qian et al.   MOLECULAR CELL

NEDD9 promotes oncogenic signaling, a stem/mesenchymal gene signature, and aggressive ovarian cancer growth in mice

(2018) Rashid Gabbasov et al.   ONCOGENE

Phosphorylation-mediated activation of LDHA promotes cancer cell invasion and tumour metastasis

(2017) L Jin et al.   ONCOGENE

c-Src phosphorylation and activation of hexokinase promotes tumorigenesis and metastasis

(2017) Jia Zhang et al.   Nature Communications

Musashi-2 (MSI2) supports TGF-β signaling and inhibits claudins to promote non-small cell lung cancer (NSCLC) metastasis

(2016) Alexander E. Kudinov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Warburg Effect: How Does it Benefit Cancer Cells?

(2016) Maria V. Liberti et al.   TRENDS IN BIOCHEMICAL SCIENCES

PKM2 dephosphorylation by Cdc25A promotes the Warburg effect and tumorigenesis

(2016) Ji Liang et al.   Nature Communications

Embryonal Fyn-associated substrate (EFS) and CASS4: The lesser-known CAS protein family members

(2015) Alexander Deneka et al.   GENE

Preclinical and clinical studies of the NEDD9 scaffold protein in cancer and other diseases

(2015) Elena Shagisultanova et al.   GENE

Rapid Analysis of Glycolytic and Oxidative Substrate Flux of Cancer Cells in a Microplate

(2014) Lisa S. Pike Winer et al.   PLoS One

Autophagy is required for mitochondrial function, lipid metabolism, growth, and fate of KRASG12D-driven lung tumors

(2013) Jessie Yanxiang Guo et al.   Autophagy

Hexokinase 2 Is Required for Tumor Initiation and Maintenance and Its Systemic Deletion Is Therapeutic in Mouse Models of Cancer

(2013) Krushna C. Patra et al.   CANCER CELL

A requirement for Nedd9 in luminal progenitor cells prior to mammary tumorigenesis in MMTV-HER2/ErbB2 mice

(2013) J L Little et al.   ONCOGENE

PP2A phosphatase suppresses function of the mesenchymal invasion regulator NEDD9

(2011) Peta Bradbury et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

NEDD9 and BCAR1 Negatively Regulate E-Cadherin Membrane Localization, and Promote E-Cadherin Degradation

(2011) Nadezhda Tikhmyanova et al.   PLoS One

Bioenergetic Profile Experiment using C2C12 Myoblast Cells

(2010) David G. Nicholls et al.   Jove-Journal of Visualized Experiments

NEDD9 Promotes Oncogenic Signaling in Mammary Tumor Development

(2009) E. Izumchenko et al.   CANCER RESEARCH

CAS proteins in normal and pathological cell growth control

(2009) Nadezhda Tikhmyanova et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Contextual extracellular cues promote tumor cell EMT and metastasis by regulating miR-200 family expression

(2009) D. L. Gibbons et al.   GENES & DEVELOPMENT

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

The Biology of Cancer: Metabolic Reprogramming Fuels Cell Growth and Proliferation

(2008) Ralph J. DeBerardinis et al.   Cell Metabolism

An Integrated Genomic Analysis of Human Glioblastoma Multiforme

(2008) D. W. Parsons et al.   SCIENCE