MitoNEET Deficiency Alleviates Experimental Alcoholic Steatohepatitis in Mice by Stimulating Endocrine Adiponectin-Fgf15 Axis

The Detrimental Role Played by Lipocalin-2 in Alcoholic Fatty Liver in Mice

(2016) Yan Cai et al.   AMERICAN JOURNAL OF PATHOLOGY

IL-1β inhibits β-Klotho expression and FGF19 signaling in hepatocytes

(2016) Yueshui Zhao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Lipocalin 2 drives neutrophilic inflammation in alcoholic liver disease

(2016) Verena Wieser et al.   JOURNAL OF HEPATOLOGY

Novel thiazolidinedione mitoNEET ligand-1 acutely improves cardiac stem cell survival under oxidative stress

(2015) Suzanna J. Logan et al.   BASIC RESEARCH IN CARDIOLOGY

Structure–function analysis of NEET proteins uncovers their role as key regulators of iron and ROS homeostasis in health and disease

(2015) Sagi Tamir et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Mechanisms of enterohepatic fibroblast growth factor 15/19 signaling in health and disease

(2015) Daniel Jahn et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Lipocalin-2 (NGAL/LCN2), a “help-me” signal in organ inflammation

(2015) Anastasia Asimakopoulou et al.   HEPATOLOGY

Engineered fibroblast growth factor 19 reduces liver injury and resolves sclerosing cholangitis in Mdr2 -deficient mice

(2015) Mei Zhou et al.   HEPATOLOGY

Circulating FGF19 and FGF21 surge in early infancy from infra- to supra-adult concentrations

(2015) D Sánchez-Infantes et al.   INTERNATIONAL JOURNAL OF OBESITY

Loss of ileum decreases serum fibroblast growth factor 19 in relation to liver inflammation and fibrosis in pediatric onset intestinal failure

(2015) Annika Mutanen et al.   JOURNAL OF HEPATOLOGY

CISD1in association with obesity-associated dysfunctional adipogenesis in human visceral adipose tissue

(2015) José María Moreno-Navarrete et al.   Obesity

Dysregulation of Mitochondrial Functions and Osteogenic Differentiation in Cisd2-Deficient Murine Induced Pluripotent Stem Cells

(2015) Ping-Hsing Tsai et al.   STEM CELLS AND DEVELOPMENT

Sustained Brown Fat Stimulation and Insulin Sensitization by a Humanized Bispecific Antibody Agonist for Fibroblast Growth Factor Receptor 1/βKlotho Complex

(2015) Ganesh Kolumam et al.   EBioMedicine

mitoNEET as a novel drug target for mitochondrial dysfunction

(2014) Werner J. Geldenhuys et al.   DRUG DISCOVERY TODAY

Cisd2 modulates the differentiation and functioning of adipocytes by regulating intracellular Ca2+ homeostasis

(2014) Chih-Hao Wang et al.   HUMAN MOLECULAR GENETICS

Fibroblast Growth Factor Receptor 4 (FGFR4) Deficiency Improves Insulin Resistance and Glucose Metabolism under Diet-induced Obesity Conditions

(2014) Hongfei Ge et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Redox Control of Human Mitochondrial Outer Membrane Protein MitoNEET [2Fe-2S] Clusters by Biological Thiols and Hydrogen Peroxide

(2014) Aaron P. Landry et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Diabetes Drug Target MitoNEET Governs a Novel Trafficking Pathway to Rebuild an Fe-S Cluster into Cytosolic Aconitase/Iron Regulatory Protein 1

(2014) Ioana Ferecatu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Minireview: Challenges and Opportunities in Development of PPAR Agonists

(2014) Matthew B. Wright et al.   MOLECULAR ENDOCRINOLOGY

Acute Ethanol Causes Hepatic Mitochondrial Depolarization in Mice: Role of Ethanol Metabolism

(2014) Zhi Zhong et al.   PLoS One

MitoNEET-mediated effects on browning of white adipose tissue

(2014) Christine M. Kusminski et al.   Nature Communications

Mitochondrial dysfunction and tissue injury by alcohol, high fat, nonalcoholic substances and pathological conditions through post-translational protein modifications

(2014) Byoung-Joon Song et al.   Redox Biology

Activation of farnesoid X receptor attenuates hepatic injury in a murine model of alcoholic liver disease

(2013) Weibin Wu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cold Exposure Promotes Atherosclerotic Plaque Growth and Instability via UCP1-Dependent Lipolysis

(2013) Mei Dong et al.   Cell Metabolism

Adiponectin Modulates DCA-Induced Inflammation via the ROS/NF-Kappa B Signaling Pathway in Esophageal Adenocarcinoma Cells

(2013) Rong Zhang et al.   DIGESTIVE DISEASES AND SCIENCES

Alteration of bile acid metabolism in the rat induced by chronic ethanol consumption

(2013) Guoxiang Xie et al.   FASEB JOURNAL

Deletion of SIRT1 From Hepatocytes in Mice Disrupts Lipin-1 Signaling and Aggravates Alcoholic Fatty Liver

(2013) Huquan Yin et al.   GASTROENTEROLOGY

Hepatic-specific lipin-1 deficiency exacerbates experimental alcohol-induced steatohepatitis in mice

(2013) Ming Hu et al.   HEPATOLOGY

Chronic plus binge ethanol feeding synergistically induces neutrophil infiltration and liver injury in mice: A critical role for E-selectin

(2013) Adeline Bertola et al.   HEPATOLOGY

Free fatty acids repress small heterodimer partner (SHP) activation and adiponectin counteracts bile acid-induced liver injury in superobese patients with nonalcoholic steatohepatitis

(2013) Lars P. Bechmann et al.   HEPATOLOGY

Mouse model of chronic and binge ethanol feeding (the NIAAA model)

(2013) Adeline Bertola et al.   Nature Protocols

Hepatic Cannabinoid Receptor Type 1 Mediates Alcohol-Induced Regulation of Bile Acid Enzyme Genes Expression Via CREBH

(2013) Dipanjan Chanda et al.   PLoS One

Serum Levels of Fibroblast Growth Factor 19 Are Inversely Associated with Coronary Artery Disease in Chinese Individuals

(2013) Yaping Hao et al.   PLoS One

Serum Concentrations of Fibroblast Growth Factors 19 and 21 in Women with Gestational Diabetes Mellitus: Association with Insulin Resistance, Adiponectin, and Polycystic Ovary Syndrome History

(2013) Dongyu Wang et al.   PLoS One

NAF-1 and mitoNEET are central to human breast cancer proliferation by maintaining mitochondrial homeostasis and promoting tumor growth

(2013) Yang-Sung Sohn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Competition of zinc ion for the [2Fe–2S] cluster binding site in the diabetes drug target protein mitoNEET

(2012) Guoqiang Tan et al.   BIOMETALS

Mitochondrial biogenesis in epithelial cancer cells promotes breast cancer tumor growth and confers autophagy resistance

(2012) Ahmed F. Salem et al.   CELL CYCLE

NADPH Inhibits [2Fe-2S] Cluster Protein Transfer from Diabetes Drug Target MitoNEET to an Apo-acceptor Protein

(2012) John A. Zuris et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MitoNEET-driven alterations in adipocyte mitochondrial activity reveal a crucial adaptive process that preserves insulin sensitivity in obesity

(2012) Christine M Kusminski et al.   NATURE MEDICINE

Alcoholic Liver Disease: Pathogenesis and New Therapeutic Targets

(2011) Bin Gao et al.   GASTROENTEROLOGY

The Receptor Tyrosine Kinase FGFR4 Negatively Regulates NF-kappaB Signaling

(2010) Kristine A. Drafahl et al.   PLoS One

Role of SIRT1 in regulation of LPS- or two ethanol metabolites-induced TNF-α production in cultured macrophage cell lines

(2009) Zheng Shen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Involvement of adiponectin-SIRT1-AMPK signaling in the protective action of rosiglitazone against alcoholic fatty liver in mice

(2009) Zheng Shen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Adiponectin: A Key Adipokine in Alcoholic Fatty Liver

(2009) Min You et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Cisd2 deficiency drives premature aging and causes mitochondria-mediated defects in mice

(2009) Y.-F. Chen et al.   GENES & DEVELOPMENT

Involvement of mammalian sirtuin 1 in the action of ethanol in the liver

(2008) Min You et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Dysregulation of systemic iron metabolism in alcoholic liver diseases

(2008) Yutaka Kohgo et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Protective properties afforded by pioglitazone against intrastriatal LPS in Sprague–Dawley rats

(2007) Randy L. Hunter et al.   NEUROSCIENCE LETTERS