Paracrine signalling between intestinal epithelial and tumour cells induces a regenerative programme

Wnt and Src signals converge on YAP‐TEAD to drive intestinal regeneration

(2021) Oriane Guillermin et al.   EMBO JOURNAL

Tracing oncogene-driven remodelling of the intestinal stem cell niche

(2021) Min Kyu Yum et al.   NATURE

NOTUM from Apc-mutant cells biases clonal competition to initiate cancer

(2021) Dustin J. Flanagan et al.   NATURE

Apc-mutant cells act as supercompetitors in intestinal tumour initiation

(2021) Sanne M. van Neerven et al.   NATURE

Active elimination of intestinal cells drives oncogenic growth in organoids

(2021) Ana Krotenberg Garcia et al.   Cell Reports

Regenerative Reprogramming of the Intestinal Stem Cell State via Hippo Signaling Suppresses Metastatic Colorectal Cancer

(2020) Priscilla Cheung et al.   Cell Stem Cell

Lineage tracing of Notch1-expressing cells in intestinal tumours reveals a distinct population of cancer stem cells

(2019) Larissa Mourao et al.   Scientific Reports

Metastatic-niche labelling reveals parenchymal cells with stem features

(2019) Luigi Ombrato et al.   NATURE

TSVdb: a web-tool for TCGA splicing variants analysis

(2018) Wenjie Sun et al.   BMC GENOMICS

YAP/TAZ-Dependent Reprogramming of Colonic Epithelium Links ECM Remodeling to Tissue Regeneration

(2018) Shiro Yui et al.   Cell Stem Cell

The PRIDE database and related tools and resources in 2019: improving support for quantification data

(2018) Yasset Perez-Riverol et al.   NUCLEIC ACIDS RESEARCH

YAP–IL-6ST autoregulatory loop activated on APC loss controls colonic tumorigenesis

(2017) Koji Taniguchi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

YAP/TAZ at the Roots of Cancer

(2016) Francesca Zanconato et al.   CANCER CELL

Role of thrombospondin-1 expression in colorectal liver metastasis and its molecular mechanism

(2016) Hiroki Teraoku et al.   Journal of Hepato-Biliary-Pancreatic Sciences

β-Catenin destruction complex-independent regulation of Hippo–YAP signaling by APC in intestinal tumorigenesis

(2015) Jing Cai et al.   GENES & DEVELOPMENT

Yap-dependent reprogramming of Lgr5+ stem cells drives intestinal regeneration and cancer

(2015) Alex Gregorieff et al.   NATURE

A gp130–Src–YAP module links inflammation to epithelial regeneration

(2015) Koji Taniguchi et al.   NATURE

Sequential cancer mutations in cultured human intestinal stem cells

(2015) Jarno Drost et al.   NATURE

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

Thrombospondin-1 in a Murine Model of Colorectal Carcinogenesis

(2015) Zenaida P. Lopez-Dee et al.   PLoS One

YAP/TAZ Incorporation in the β-Catenin Destruction Complex Orchestrates the Wnt Response

(2014) Luca Azzolin et al.   CELL

CRISPR-Cas9 Knockin Mice for Genome Editing and Cancer Modeling

(2014) Randall J. Platt et al.   CELL

Current understanding of the thrombospondin-1 interactome

(2014) Andrea Resovi et al.   MATRIX BIOLOGY

Tumour cell heterogeneity maintained by cooperating subclones in Wnt-driven mammary cancers

(2014) Allison S. Cleary et al.   NATURE

Non-cell-autonomous driving of tumour growth supports sub-clonal heterogeneity

(2014) Andriy Marusyk et al.   NATURE

Improved vectors and genome-wide libraries for CRISPR screening

(2014) Neville E Sanjana et al.   NATURE METHODS

Tripartite interactions between Wnt signaling, Notch and Myb for stem/progenitor cell functions during intestinal tumorigenesis

(2014) Markus Germann et al.   Stem Cell Research

Functional Repair of CFTR by CRISPR/Cas9 in Intestinal Stem Cell Organoids of Cystic Fibrosis Patients

(2013) Gerald Schwank et al.   Cell Stem Cell

The tumor microenvironment at a glance

(2013) F. R. Balkwill et al.   JOURNAL OF CELL SCIENCE

Genetic reconstitution of tumorigenesis in primary intestinal cells

(2013) K. Onuma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Growing Self-Organizing Mini-Guts from a Single Intestinal Stem Cell: Mechanism and Applications

(2013) T. Sato et al.   SCIENCE

Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells

(2013) Ophir Shalem et al.   SCIENCE

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment

(2012) Douglas Hanahan et al.   CANCER CELL

Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP

(2012) Y. Liu-Chittenden et al.   GENES & DEVELOPMENT

Restriction of intestinal stem cell expansion and the regenerative response by YAP

(2012) Evan R. Barry et al.   NATURE

In vivo and in vitro models for the therapeutic targeting of Wnt signaling using a Tet-OΔN89β-catenin system

(2012) T Jardé et al.   ONCOGENE

The Intestinal Stem Cell Signature Identifies Colorectal Cancer Stem Cells and Predicts Disease Relapse

(2011) Anna Merlos-Suárez et al.   Cell Stem Cell

Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium

(2011) Toshiro Sato et al.   GASTROENTEROLOGY

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

(2009) Toshiro Sato et al.   NATURE

Thrombospondin-1 enhances human thyroid carcinoma cell invasion through urokinase activity

(2008) Brice Sid et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Crypt stem cells as the cells-of-origin of intestinal cancer

(2008) Nick Barker et al.   NATURE

Lifeact: a versatile marker to visualize F-actin

(2008) Julia Riedl et al.   NATURE METHODS