Active elimination of intestinal cells drives oncogenic growth in organoids

Genetic and clinical correlates of entosis in pancreatic ductal adenocarcinoma

(2020) Akimasa Hayashi et al.   MODERN PATHOLOGY

Distinct modes of cell competition shape mammalian tissue morphogenesis

(2019) Stephanie J. Ellis et al.   NATURE

WebGestalt 2019: gene set analysis toolkit with revamped UIs and APIs

(2019) Yuxing Liao et al.   NUCLEIC ACIDS RESEARCH

Cell competition: the winners and losers of fitness selection

(2019) Sarah Bowling et al.   DEVELOPMENT

Flower isoforms promote competitive growth in cancer

(2019) Esha Madan et al.   NATURE

Epithelial NOTCH Signaling Rewires the Tumor Microenvironment of Colorectal Cancer to Drive Poor-Prognosis Subtypes and Metastasis

(2019) Rene Jackstadt et al.   CANCER CELL

Long-Term Culture Captures Injury-Repair Cycles of Colonic Stem Cells

(2019) Yi Wang et al.   CELL

Peritumoral activation of the Hippo pathway effectors YAP and TAZ suppresses liver cancer in mice

(2019) Iván M. Moya et al.   SCIENCE

YAP/TAZ-Dependent Reprogramming of Colonic Epithelium Links ECM Remodeling to Tissue Regeneration

(2018) Shiro Yui et al.   Cell Stem Cell

Enteroid Monolayers Reveal an Autonomous WNT and BMP Circuit Controlling Intestinal Epithelial Growth and Organization

(2018) Curtis A. Thorne et al.   DEVELOPMENTAL CELL

Obesity Suppresses Cell-Competition-Mediated Apical Elimination of RasV12-Transformed Cells from Epithelial Tissues

(2018) Ayana Sasaki et al.   Cell Reports

Parasitic helminths induce fetal-like reversion in the intestinal stem cell niche

(2018) Ysbrand M. Nusse et al.   NATURE

Correction of aberrant growth preserves tissue homeostasis

(2017) Samara Brown et al.   NATURE

Cell competition with normal epithelial cells promotes apical extrusion of transformed cells through metabolic changes

(2017) Shunsuke Kon et al.   NATURE CELL BIOLOGY

Live-cell measurements of kinase activity in single cells using translocation reporters

(2017) Takamasa Kudo et al.   Nature Protocols

Genetic dissection of colorectal cancer progression by orthotopic transplantation of engineered cancer organoids

(2017) Arianna Fumagalli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell Competition: Mechanisms and Physiological Roles

(2016) Cristina Clavería et al.   Annual Review of Cell and Developmental Biology

Cell Competition Drives the Growth of Intestinal Adenomas in Drosophila

(2016) Saskia J.E. Suijkerbuijk et al.   CURRENT BIOLOGY

Elimination of Unfit Cells Maintains Tissue Health and Prolongs Lifespan

(2015) Marisa M. Merino et al.   CELL

Cell Competition Modifies Adult Stem Cell and Tissue Population Dynamics in a JAK-STAT-Dependent Manner

(2015) Golnar Kolahgar et al.   DEVELOPMENTAL CELL

Yap-dependent reprogramming of Lgr5+ stem cells drives intestinal regeneration and cancer

(2015) Alex Gregorieff et al.   NATURE

The consensus molecular subtypes of colorectal cancer

(2015) Justin Guinney et al.   NATURE MEDICINE

Cancers Complicating Inflammatory Bowel Disease

(2015) Laurent Beaugerie et al.   NEW ENGLAND JOURNAL OF MEDICINE

Intestinal Epithelial Cell Up-Regulation of LY6 Molecules during Colitis Results in Enhanced Chemokine Secretion

(2014) K. Flanagan et al.   JOURNAL OF IMMUNOLOGY

Transformation of intestinal stem cells into gastric stem cells on loss of transcription factor Cdx2

(2014) Salvatore Simmini et al.   Nature Communications

Competitive Interactions Eliminate Unfit Embryonic Stem Cells at the Onset of Differentiation

(2013) Margarida Sancho et al.   DEVELOPMENTAL CELL

Myc-driven endogenous cell competition in the early mammalian embryo

(2013) Cristina Clavería et al.   NATURE

Niche-independent high-purity cultures of Lgr5+ intestinal stem cells and their progeny

(2013) Xiaolei Yin et al.   NATURE METHODS

Discovery of Potent and Selective Covalent Inhibitors of JNK

(2012) Tinghu Zhang et al.   CHEMISTRY & BIOLOGY

Crowding induces live cell extrusion to maintain homeostatic cell numbers in epithelia

(2012) George T. Eisenhoffer et al.   NATURE

CEL-Seq: Single-Cell RNA-Seq by Multiplexed Linear Amplification

(2012) Tamar Hashimshony et al.   Cell Reports

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Cell competition and its implications for development and cancer

(2011) Yoichiro Tamori et al.   Journal of Genetics and Genomics

A reserve stem cell population in small intestine renders Lgr5-positive cells dispensable

(2011) Hua Tian et al.   NATURE

Fast and accurate long-read alignment with Burrows–Wheeler transform

(2010) Heng Li et al.   BIOINFORMATICS

Intestinal Crypt Homeostasis Results from Neutral Competition between Symmetrically Dividing Lgr5 Stem Cells

(2010) Hugo J. Snippert et al.   CELL

Intestinal Stem Cell Replacement Follows a Pattern of Neutral Drift

(2010) C. Lopez-Garcia et al.   SCIENCE

Dedifferentiating Spermatogonia Outcompete Somatic Stem Cells for Niche Occupancy in the Drosophila Testis

(2009) X. Rebecca Sheng et al.   Cell Stem Cell

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

(2009) Toshiro Sato et al.   NATURE

A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses

(2009) Shaoguang Wu et al.   NATURE MEDICINE