In vivo and in vitro models for the therapeutic targeting of Wnt signaling using a Tet-OΔN89β-catenin system

Intestinal renin–angiotensin system is stimulated after deletion of Lkb1

(2011) Boris Y Shorning et al.   GUT

Maintenance of adenomatous polyposis coli (APC)-mutant colorectal cancer is dependent on Wnt/ -catenin signaling

(2011) A. Scholer-Dahirel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Useful Approach to Identify Novel Small-Molecule Inhibitors of Wnt-Dependent Transcription

(2010) K. Ewan et al.   CANCER RESEARCH

Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts

(2010) Toshiro Sato et al.   NATURE

A Re-evaluation of the “Oncogenic” Nature of Wnt/β-catenin Signaling in Melanoma and Other Cancers

(2010) Olivia M. Lucero et al.   Current Oncology Reports

Genetic Dissection of Differential Signaling Threshold Requirements for the Wnt/β-Catenin Pathway In Vivo

(2010) Michael Buchert et al.   PLoS Genetics

Wnt/Planar cell polarity signaling: A new paradigm for cancer therapy

(2009) Y. Wang   MOLECULAR CANCER THERAPEUTICS

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

(2009) Toshiro Sato et al.   NATURE

Stem Cells, Self-Renewal, and Differentiation in the Intestinal Epithelium

(2008) Laurens G. van der Flier et al.   Annual Review of Physiology

Small molecule inhibitors of WNT signaling effectively induce apoptosis in acute myeloid leukemia cells

(2008) Katharina Salome Minke et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

Alternative Wnt Signaling Is Initiated by Distinct Receptors

(2008) R. van Amerongen et al.   Science Signaling