Epitope-dependent Functional Effects of Celiac Disease Autoantibodies on Transglutaminase 2

Dissecting the interaction between transglutaminase 2 and fibronectin

(2016) Inês Cardoso et al.   AMINO ACIDS

Small Bowel, Celiac Disease and Adaptive Immunity

(2015) Ludvig M. Sollid et al.   DIGESTIVE DISEASES

Transglutaminase 2 interactions with extracellular matrix proteins as probed with celiac disease autoantibodies

(2015) Inês Cardoso et al.   FEBS Journal

Structural Basis for Antigen Recognition by Transglutaminase 2-specific Autoantibodies in Celiac Disease

(2015) Xi Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

P2X7 receptor activation regulates rapid unconventional export of transglutaminase-2

(2015) M. Adamczyk et al.   JOURNAL OF CELL SCIENCE

Analysis of Celiac Disease Autoreactive Gut Plasma Cells and Their Corresponding Memory Compartment in Peripheral Blood Using High-Throughput Sequencing

(2015) Omri Snir et al.   JOURNAL OF IMMUNOLOGY

Igs as Substrates for Transglutaminase 2: Implications for Autoantibody Production in Celiac Disease

(2015) R. Iversen et al.   JOURNAL OF IMMUNOLOGY

Crystal Structure of Transglutaminase 2 with GTP Complex and Amino Acid Sequence Evidence of Evolution of GTP Binding Site

(2014) Tae-Ho Jang et al.   PLoS One

Activity-regulating structural changes and autoantibody epitopes in transglutaminase 2 assessed by hydrogen/deuterium exchange

(2014) Rasmus Iversen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of a specific one amino acid change in recombinant human transglutaminase 2 that regulates its activity and calcium sensitivity

(2013) Kajal Kanchan et al.   BIOCHEMICAL JOURNAL

Transglutaminase 2-Specific Autoantibodies in Celiac Disease Target Clustered, N-Terminal Epitopes Not Displayed on the Surface of Cells

(2013) R. Iversen et al.   JOURNAL OF IMMUNOLOGY

Celiac Disease–Specific TG2-Targeted Autoantibodies Inhibit Angiogenesis Ex Vivo and In Vivo in Mice by Interfering with Endothelial Cell Dynamics

(2013) Suvi Kalliokoski et al.   PLoS One

Erosive Rheumatoid Arthritis Is Associated with Antibodies That Activate PAD4 by Increasing Calcium Sensitivity

(2013) E. Darrah et al.   Science Translational Medicine

High abundance of plasma cells secreting transglutaminase 2–specific IgA autoantibodies with limited somatic hypermutation in celiac disease intestinal lesions

(2012) Roberto Di Niro et al.   NATURE MEDICINE

Celiac disease and transglutaminase 2: a model for posttranslational modification of antigens and HLA association in the pathogenesis of autoimmune disorders

(2011) Ludvig M Sollid et al.   CURRENT OPINION IN IMMUNOLOGY

Extracellular TG2: emerging functions and regulation

(2011) Alexey M. Belkin   FEBS Journal

Activation of Extracellular Transglutaminase 2 by Thioredoxin

(2011) Xi Jin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Posttranslational Modification of Gluten Shapes TCR Usage in Celiac Disease

(2011) S.-W. Qiao et al.   JOURNAL OF IMMUNOLOGY

Anti-Tissue Transglutaminase Antibodies From Celiac Patients Are Responsible for Trophoblast Damage via Apoptosis In Vitro

(2010) Nicoletta Di Simone et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Coeliac disease-specific autoantibodies targeted against transglutaminase 2 disturb angiogenesis

(2010) E. Myrsky et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Crystal structure of human transglutaminase 2 in complex with adenosine triphosphate

(2010) Byeong-Gu Han et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Redox Regulation of Transglutaminase 2 Activity

(2010) Jorunn Stamnaes et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Celiac disease IgA modulates vascular permeability in vitro through the activity of transglutaminase 2 and RhoA

(2009) Essi Myrsky et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Functional significance of five noncanonical Ca2+-binding sites of human transglutaminase 2 characterized by site-directed mutagenesis

(2009) Róbert Király et al.   FEBS Journal

Tissue transglutaminase in celiac disease: role of autoantibodies

(2008) Ivana Caputo et al.   AMINO ACIDS

Extracellular Transglutaminase 2 Is Catalytically Inactive, but Is Transiently Activated upon Tissue Injury

(2008) Matthew Siegel et al.   PLoS One