Erosive Rheumatoid Arthritis Is Associated with Antibodies That Activate PAD4 by Increasing Calcium Sensitivity

Histone Deimination As a Response to Inflammatory Stimuli in Neutrophils

(2014) I. Neeli et al.   JOURNAL OF IMMUNOLOGY

The influence of ACPA status and characteristics on the course of RA

(2012) Annemiek Willemze et al.   Nature Reviews Rheumatology

Pre-rheumatoid arthritis: predisposition and transition to clinical synovitis

(2012) William P. Arend et al.   Nature Reviews Rheumatology

Peptidylarginine deiminase 2, 3 and 4 have distinct specificities against cellular substrates: novel insights into autoantigen selection in rheumatoid arthritis

(2011) Erika Darrah et al.   ANNALS OF THE RHEUMATIC DISEASES

N-α-Benzoyl-N5-(2-Chloro-1-Iminoethyl)-l-Ornithine Amide, a Protein Arginine Deiminase Inhibitor, Reduces the Severity of Murine Collagen-Induced Arthritis

(2011) Van C. Willis et al.   JOURNAL OF IMMUNOLOGY

Anti-PAD4 autoantibodies in rheumatoid arthritis: levels in serum over time and impact on PAD4 activity as measured with a small synthetic substrate

(2011) Sylvie Pollmann et al.   RHEUMATOLOGY INTERNATIONAL

Autoimmunity to peptidyl arginine deiminase type 4 precedes clinical onset of rheumatoid arthritis

(2010) Jason R. Kolfenbach et al.   ARTHRITIS AND RHEUMATISM

Autocitrullination of human peptidyl arginine deiminase type 4 regulates protein citrullination during cell activation

(2010) Felipe Andrade et al.   ARTHRITIS AND RHEUMATISM

Substrate Specificity and Kinetic Studies of PADs 1, 3, and 4 Identify Potent and Selective Inhibitors of Protein Arginine Deiminase 3

(2010) Bryan Knuckley et al.   BIOCHEMISTRY

Rheumatoid arthritis–specific autoantibodies to peptidyl arginine deiminase type 4 inhibit citrullination of fibrinogen

(2009) Isabelle Auger et al.   ARTHRITIS AND RHEUMATISM

Autoantigens in systemic autoimmunity: critical partner in pathogenesis

(2009) A. Rosen et al.   JOURNAL OF INTERNAL MEDICINE

Serum IgG antibodies to peptidylarginine deiminase 4 predict radiographic progression in patients with rheumatoid arthritis treated with tumour necrosis factor-  blocking agents

(2008) E H Halvorsen et al.   ANNALS OF THE RHEUMATIC DISEASES

Association of autoimmunity to peptidyl arginine deiminase type 4 with genotype and disease severity in rheumatoid arthritis

(2008) Michelle L. Harris et al.   ARTHRITIS AND RHEUMATISM

Synovial fluid is a site of citrullination of autoantigens in inflammatory arthritis

(2008) Andrew Kinloch et al.   ARTHRITIS AND RHEUMATISM