Notch-mediated lactate metabolism regulates MDSC development through the Hes1/MCT2/c-Jun axis
出版年份 2022 全文链接
标题
Notch-mediated lactate metabolism regulates MDSC development through the Hes1/MCT2/c-Jun axis
作者
关键词
notch signaling, MDSC, TAM, lactate, MCT2, c-Jun
出版物
Cell Reports
Volume 38, Issue 10, Pages 110451
出版商
Elsevier BV
发表日期
2022-03-09
DOI
10.1016/j.celrep.2022.110451
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Monocarboxylate Transporters (SLC16): Function, Regulation, and Role in Health and Disease
- (2020) Melanie A. Felmlee et al. PHARMACOLOGICAL REVIEWS
- Notch signaling via Wnt regulates the proliferation of alternative, CCR2-independent tumor-associated macrophages in hepatocellular carcinoma
- (2019) Yu-Chen Ye et al. CANCER RESEARCH
- Identification of monocyte-like precursors of granulocytes in cancer as a mechanism for accumulation of PMN-MDSCs
- (2019) Jérôme Mastio et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Ketogenic diet in cancer therapy
- (2018) Daniela D. Weber et al. Aging-US
- Downregulating Notch counteracts KrasG12D-induced ERK activation and oxidative phosphorylation in myeloproliferative neoplasm
- (2018) Guangyao Kong et al. LEUKEMIA
- Notch Signaling Modulates Macrophage Polarization and Phagocytosis Through Direct Suppression of Signal Regulatory Protein α Expression
- (2018) Yan Lin et al. Frontiers in Immunology
- Treatment of malignant gliomas with ketogenic or caloric restricted diets: A systematic review of preclinical and early clinical studies
- (2018) Lotte Noorlag et al. CLINICAL NUTRITION
- Tumor immunoevasion via acidosis-dependent induction of regulatory tumor-associated macrophages
- (2018) Toszka Bohn et al. NATURE IMMUNOLOGY
- Ketogenic diet treatment in recurrent diffuse intrinsic pontine glioma in children: A safety and feasibility study
- (2018) Elles J.T.M. van der Louw et al. PEDIATRIC BLOOD & CANCER
- COX2/mPGES1/PGE2pathway regulates PD-L1 expression in tumor-associated macrophages and myeloid-derived suppressor cells
- (2017) Victor Prima et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Gpr132 sensing of lactate mediates tumor–macrophage interplay to promote breast cancer metastasis
- (2017) Peiwen Chen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- miR-148a-3p Mediates Notch Signaling to Promote the Differentiation and M1 Activation of Macrophages
- (2017) Fei Huang et al. Frontiers in Immunology
- Forced Activation of Notch in Macrophages Represses Tumor Growth by Upregulating miR-125a and Disabling Tumor-Associated Macrophages
- (2016) Jun-Long Zhao et al. CANCER RESEARCH
- Lactate as a predictive marker for tumor recurrence in patients with head and neck squamous cell carcinoma (HNSCC) post radiation: a prospective study over 15 years
- (2016) Sebastian Blatt et al. Clinical Oral Investigations
- The blockage of Notch signalling promoted the generation of polymorphonuclear myeloid-derived suppressor cells with lower immunosuppression
- (2016) Shu-Hong Wang et al. EUROPEAN JOURNAL OF CANCER
- CD45 Phosphatase Inhibits STAT3 Transcription Factor Activity in Myeloid Cells and Promotes Tumor-Associated Macrophage Differentiation
- (2016) Vinit Kumar et al. IMMUNITY
- The Nature of Myeloid-Derived Suppressor Cells in the Tumor Microenvironment
- (2016) Vinit Kumar et al. TRENDS IN IMMUNOLOGY
- Recommendations for myeloid-derived suppressor cell nomenclature and characterization standards
- (2016) Vincenzo Bronte et al. Nature Communications
- MCT4 as a potential therapeutic target for metastatic gastric cancer with peritoneal carcinomatosis
- (2016) Ji Yun Lee et al. Oncotarget
- Activated hepatic stellate cells promote liver cancer by induction of myeloid-derived suppressor cells through cyclooxygenase-2
- (2016) Yaping Xu et al. Oncotarget
- Role of Notch signaling in regulating innate immunity and inflammation in health and disease
- (2016) Yingli Shang et al. Protein & Cell
- RORC1 Regulates Tumor-Promoting “Emergency” Granulo-Monocytopoiesis
- (2015) Laura Strauss et al. CANCER CELL
- A Lactate-Induced Response to Hypoxia
- (2015) Dong Chul Lee et al. CELL
- Metabolic Reprogramming of Immune Cells in Cancer Progression
- (2015) Subhra K. Biswas IMMUNITY
- NOTCH reprograms mitochondrial metabolism for proinflammatory macrophage activation
- (2015) Jun Xu et al. JOURNAL OF CLINICAL INVESTIGATION
- Serum lactate as a potential biomarker of malignancy in primary adult brain tumours
- (2015) Ramamani Mariappan et al. JOURNAL OF CLINICAL NEUROSCIENCE
- Modeling Alveolar Soft Part Sarcomagenesis in the Mouse: A Role for Lactate in the Tumor Microenvironment
- (2014) Matthew L. Goodwin et al. CANCER CELL
- Myeloid-specific disruption of recombination signal binding protein Jκameliorates hepatic fibrosis by attenuating inflammation through cylindromatosis in mice
- (2014) Fei He et al. HEPATOLOGY
- Functional polarization of tumour-associated macrophages by tumour-derived lactic acid
- (2014) Oscar R. Colegio et al. NATURE
- Notch controls the survival of memory CD4+ T cells by regulating glucose uptake
- (2014) Yoichi Maekawa et al. NATURE MEDICINE
- Acquisition of an immunosuppressive protumorigenic macrophage phenotype depending on c-Jun phosphorylation
- (2014) Simona Hefetz-Sela et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Lactate promotes plasticity gene expression by potentiating NMDA signaling in neurons
- (2014) J. Yang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The cellular and molecular origin of tumor-associated macrophages
- (2014) R. A. Franklin et al. SCIENCE
- Lactate-mediated glia-neuronal signalling in the mammalian brain
- (2014) F. Tang et al. Nature Communications
- TargetHunter: An In Silico Target Identification Tool for Predicting Therapeutic Potential of Small Organic Molecules Based on Chemogenomic Database
- (2013) Lirong Wang et al. AAPS Journal
- M-CSF cooperating with NFκB induces macrophage transformation from M1 to M2 by upregulating c-Jun
- (2013) Yujiao Yang et al. CANCER BIOLOGY & THERAPY
- Effects of Notch Signaling on Regulation of Myeloid Cell Differentiation in Cancer
- (2013) P. Cheng et al. CANCER RESEARCH
- Targeting lactate metabolism for cancer therapeutics
- (2013) Joanne R. Doherty et al. JOURNAL OF CLINICAL INVESTIGATION
- Tumor-Derived Lactate Modifies Antitumor Immune Response: Effect on Myeloid-Derived Suppressor Cells and NK Cells
- (2013) Z. Husain et al. JOURNAL OF IMMUNOLOGY
- Epigenetic silencing of retinoblastoma gene regulates pathologic differentiation of myeloid cells in cancer
- (2013) Je-In Youn et al. NATURE IMMUNOLOGY
- Tumor-associated macrophages: functional diversity, clinical significance, and open questions
- (2013) Subhra K. Biswas et al. Seminars in Immunopathology
- Notch–RBP-J signaling regulates the transcription factor IRF8 to promote inflammatory macrophage polarization
- (2012) Haixia Xu et al. NATURE IMMUNOLOGY
- Notch Signaling Determines the M1 versus M2 Polarization of Macrophages in Antitumor Immune Responses
- (2010) Yao-Chun Wang et al. CANCER RESEARCH
- The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism
- (2009) Raphael Kopan et al. CELL
- Role of GPR81 in lactate-mediated reduction of adipose lipolysis
- (2008) Tian-Quan Cai et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
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