Novel 2-(5-Aryl-4,5-Dihydropyrazol-1-yl)thiazol-4-One as EGFR Inhibitors: Synthesis, Biological Assessment and Molecular Docking Insights
出版年份 2022 全文链接
标题
Novel 2-(5-Aryl-4,5-Dihydropyrazol-1-yl)thiazol-4-One as EGFR Inhibitors: Synthesis, Biological Assessment and Molecular Docking Insights
作者
关键词
-
出版物
Drug Design Development and Therapy
Volume Volume 16, Issue -, Pages 1457-1471
出版商
Informa UK Limited
发表日期
2022-05-16
DOI
10.2147/dddt.s356988
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Clocks, cancer, and chronochemotherapy
- (2021) Aziz Sancar et al. SCIENCE
- Development of isatin-thiazolo[3,2-a]benzimidazole hybrids as novel CDK2 inhibitors with potent in vitro apoptotic anti-proliferative activity: Synthesis, biological and molecular dynamics investigations
- (2021) Wagdy M. Eldehna et al. BIOORGANIC CHEMISTRY
- Antiproliferative activity of thiazole and oxazole derivatives: A systematic review of in vitro and in vivo studies
- (2021) Nancy Y. Guerrero-Pepinosa et al. BIOMEDICINE & PHARMACOTHERAPY
- Synthesis and biological evaluation of halogenated phenoxychalcones and their corresponding pyrazolines as cytotoxic agents in human breast cancer
- (2021) Peter A. Halim et al. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
- Dual Kinase Inhibition of EGFR/HER2: Design, Synthesis and Molecular Docking of Thiazolylpyrazolyl‐Based Aminoquinoline Derivatives as Anticancer Agents**
- (2021) Rasha Z. Batran et al. ChemistrySelect
- Targeted Therapies in Cancer: To Be or Not to Be, Selective
- (2021) Skye Montoya et al. Biomedicines
- Design and Synthesis of some new 2,4,6-trisubstituted quinazoline EGFR inhibitors as targeted anticancer agents
- (2020) Heba Abdelrasheed Allam et al. BIOORGANIC CHEMISTRY
- Design, Synthesis, Molecular Docking and Anticancer Evaluation of Pyrazole Linked Pyrazoline Derivatives with Carbothioamide tail as EGFR Kinase Inhibitors
- (2020) Farah Nawaz et al. Anti-Cancer Agents in Medicinal Chemistry
- A review on progression of epidermal growth factor receptor (EGFR) inhibitors as an efficient approach in cancer targeted therapy
- (2020) Adileh Ayati et al. BIOORGANIC CHEMISTRY
- Some 1,3,5-trisubstituted pyrazoline derivatives targeting breast cancer: Design, synthesis, cytotoxic activity, EGFR inhibition and molecular docking
- (2020) Riham F. George et al. BIOORGANIC CHEMISTRY
- Pyrazoline Hybrids as Promising Anticancer Agents: An Up-to-Date Overview
- (2020) Dimitris Matiadis et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Novel oxindole/benzofuran hybrids as potential dual CDK2/GSK-3β inhibitors targeting breast cancer: design, synthesis, biological evaluation, and in silico studies
- (2020) Wagdy M. Eldehna et al. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
- Novel pyrazolo[3,4-d]pyrimidines: design, synthesis, anticancer activity, dual EGFR/ErbB2 receptor tyrosine kinases inhibitory activity, effects on cell cycle profile and caspase-3-mediated apoptosis
- (2019) Mai Maher et al. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
- Synthesis, anticancer effect and molecular modeling of new thiazolylpyrazolyl coumarin derivatives targeting VEGFR-2 kinase and inducing cell cycle arrest and apoptosis
- (2019) Tahia K. Mohamed et al. BIOORGANIC CHEMISTRY
- Thiazole in the targeted anticancer drug discovery
- (2019) Adileh Ayati et al. Future Medicinal Chemistry
- Synthesis and in vitro anticancer evaluation of some fused indazoles, quinazolines and quinolines as potential EGFR inhibitors
- (2019) Esraa A. Abdelsalam et al. BIOORGANIC CHEMISTRY
- Recent advances of thiazole hybrids in biological applications
- (2019) Mehmet Gümüş et al. Future Medicinal Chemistry
- Synthesis of some novel pyrazoline‐thiazole hybrids and their antimicrobial activities
- (2019) Doaa M. Masoud et al. JOURNAL OF HETEROCYCLIC CHEMISTRY
- Design, synthesis and biological evaluation of a new series of thiazolyl-pyrazolines as dual EGFR and HER2 inhibitors
- (2019) Belgin Sever et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Thiazole-containing compounds as therapeutic targets for cancer therapy
- (2019) Prabodh Chander Sharma et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- A Comprehensive Review on Recent Developments in the Field of Biological Applications of Potent Pyrazolines Derived from Chalcone Precursors
- (2018) Vinutha V. Salian et al. Letters in Drug Design & Discovery
- Anticancer Potential of Thiazole Derivatives: A Retrospective Review
- (2018) Shweta Jain et al. MINI-REVIEWS IN MEDICINAL CHEMISTRY
- Epidermal growth factor receptor expression affects proliferation and apoptosis in non-small cell lung cancer cells via the extracellular signal-regulated kinase/microRNA 200a signaling pathway
- (2018) Ping Zhou et al. Oncology Letters
- A Review on Recent Synthetic Strategies and Pharmacological Importance of 1,3-Thiazole Derivatives
- (2018) Swarna Gowri et al. MINI-REVIEWS IN MEDICINAL CHEMISTRY
- Synthesis and anti-proliferative activity of some new quinoline based 4,5-dihydropyrazoles and their thiazole hybrids as EGFR inhibitors
- (2018) Riham F. George et al. BIOORGANIC CHEMISTRY
- Synthesis of piperazine-based thiazolidinones as VEGFR2 tyrosine kinase inhibitors inducing apoptosis
- (2017) Mostafa MM El-Miligy et al. Future Medicinal Chemistry
- Unveiling a versatile heterocycle: pyrazoline – a review
- (2017) Beena Varghese et al. RSC Advances
- Synthetic approaches, structure activity relationship and biological applications for pharmacologically attractive pyrazole/pyrazoline–thiazolidine-based hybrids
- (2016) Dmytro Havrylyuk et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Current developments of coumarin-based anti-cancer agents in medicinal chemistry
- (2015) Saeed Emami et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Synthesis and biological evaluation of compounds which contain pyrazole, thiazole and naphthalene ring as antitumor agents
- (2014) Ji-Wen Yuan et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Synthesis, molecular modeling and biological evaluation of cinnamic acid derivatives with pyrazole moieties as novel anticancer agents
- (2014) Wei-Ming Zhang et al. RSC Advances
- Design, synthesis and biological evaluation of pyrazolyl-thiazolinone derivatives as potential EGFR and HER-2 kinase inhibitors
- (2012) Ke-Ming Qiu et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Role of epidermal growth factor receptor in breast cancer
- (2012) Hiroko Masuda et al. BREAST CANCER RESEARCH AND TREATMENT
- Recent advances in the therapeutic applications of pyrazolines
- (2012) Mohamed R Shaaban et al. EXPERT OPINION ON THERAPEUTIC PATENTS
- Gefitinib Inhibits the Proliferation of Pancreatic Cancer Cells via Cell Cycle Arrest
- (2009) Xiaohua Zhou et al. Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology
- Epidermal growth factor receptor in relation to tumor development: EGFR-targeted anticancer therapy
- (2009) Isamu Okamoto FEBS Journal
- Discovery of 4-Substituted Methoxybenzoyl-aryl-thiazole as Novel Anticancer Agents: Synthesis, Biological Evaluation, and Structure−Activity Relationships
- (2009) Yan Lu et al. JOURNAL OF MEDICINAL CHEMISTRY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More