Mechanical regulation of synapse formation and plasticity

Photoactivatable CaMKII induces synaptic plasticity in single synapses

(2021) Akihiro C. E. Shibata et al.   Nature Communications

Shootin1a-mediated actin-adhesion coupling generates force to trigger structural plasticity of dendritic spines

(2021) Ria Fajarwati Kastian et al.   Cell Reports

Mechanosensitive axon outgrowth mediated by L1-laminin clutch interface

(2021) Kouki Abe et al.   BIOPHYSICAL JOURNAL

Dendritic Spine Initiation in Brain Development, Learning and Diseases and Impact of BAR-Domain Proteins

(2021) Pushpa Khanal et al.   Cells

Mechanical actions of dendritic-spine enlargement on presynaptic exocytosis

(2021) Hasan Ucar et al.   NATURE

Rac1 is a downstream effector of PKCα in structural synaptic plasticity

(2020) Xun Tu et al.   Scientific Reports

Mechanistic advances in axon pathfinding

(2020) Laura E. McCormick et al.   CURRENT OPINION IN CELL BIOLOGY

Neuronal BIN1 Regulates Presynaptic Neurotransmitter Release and Memory Consolidation

(2020) Pierre De Rossi et al.   Cell Reports

Regulation of actin dynamics in dendritic spines: nanostructure, molecular mobility, and signaling mechanisms

(2020) Shigeo Okabe   MOLECULAR AND CELLULAR NEUROSCIENCE

The state of the septin cytoskeleton from assembly to function

(2020) Benjamin L. Woods et al.   CURRENT OPINION IN CELL BIOLOGY

Developmental and postdevelopmental roles of septins in the brain

(2020) Natsumi Ageta-Ishihara et al.   NEUROSCIENCE RESEARCH

BIN1 recovers tauopathy-induced long-term memory deficits in mice and interacts with Tau through Thr348 phosphorylation

(2019) Maxime Sartori et al.   ACTA NEUROPATHOLOGICA

Reciprocal Activation within a Kinase-Effector Complex Underlying Persistence of Structural LTP

(2019) Takeo Saneyoshi et al.   NEURON

Exercise-induced enhancement of synaptic function triggered by the inverse BAR protein, Mtss1L

(2019) Christina Chatzi et al.   eLife

MIM-Deficient Mice Exhibit Anatomical Changes in Dendritic Spines, Cortex Volume and Brain Ventricles, and Functional Changes in Motor Coordination and Learning

(2019) Rimante Minkeviciene et al.   Frontiers in Molecular Neuroscience

Synaptic nanomodules underlie the organization and plasticity of spine synapses

(2018) Martin Hruska et al.   NATURE NEUROSCIENCE

Dendritic structural plasticity and neuropsychiatric disease

(2018) Marc P. Forrest et al.   NATURE REVIEWS NEUROSCIENCE

Grip and slip of L1-CAM on adhesive substrates direct growth cone haptotaxis

(2018) Kouki Abe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell adhesion and matricellular support by astrocytes of the tripartite synapse

(2018) Anne E.J. Hillen et al.   PROGRESS IN NEUROBIOLOGY

Gradient-reading and mechano-effector machinery for netrin-1-induced axon guidance

(2018) Kentarou Baba et al.   eLife

Neurofilament light interaction with GluN1 modulates neurotransmission and schizophrenia-associated behaviors

(2018) Aidong Yuan et al.   Translational Psychiatry

The Emerging Role of Mechanics in Synapse Formation and Plasticity

(2018) Devrim Kilinc   Frontiers in Cellular Neuroscience

Shootin1b Mediates a Mechanical Clutch to Produce Force for Neuronal Migration

(2018) Takunori Minegishi et al.   Cell Reports

βIII Spectrin Is Necessary for Formation of the Constricted Neck of Dendritic Spines and Regulation of Synaptic Activity in Neurons

(2017) Nadia Efimova et al.   JOURNAL OF NEUROSCIENCE

CaMKII Autophosphorylation Is Necessary for Optimal Integration of Ca 2+ Signals during LTP Induction, but Not Maintenance

(2017) Jui-Yun Chang et al.   NEURON

CNS Neurons Deposit Laminin α5 to Stabilize Synapses

(2017) Mitchell H. Omar et al.   Cell Reports

Actin cytoskeleton in dendritic spine development and plasticity

(2016) Wenliang Lei et al.   CURRENT OPINION IN NEUROBIOLOGY

Rho GTPase complementation underlies BDNF-dependent homo- and heterosynaptic plasticity

(2016) Nathan G. Hedrick et al.   NATURE

Integrins in synapse regulation

(2016) Yun Kyung Park et al.   NATURE REVIEWS NEUROSCIENCE

Transport of a kinesin-cargo pair along microtubules into dendritic spines undergoing synaptic plasticity

(2016) Derrick P. McVicker et al.   Nature Communications

In vivo imaging demonstrates dendritic spine stabilization by SynCAM 1

(2016) Nils Körber et al.   Scientific Reports

Multicolour Multilevel STED nanoscopy of Actin/Spectrin Organization at Synapses

(2016) Sven C. Sidenstein et al.   Scientific Reports

Periodic F-actin structures shape the neck of dendritic spines

(2016) Julia Bär et al.   Scientific Reports

Saturated Reconstruction of a Volume of Neocortex

(2015) Narayanan Kasthuri et al.   CELL

Tuning synapses by proteolytic remodeling of the adhesive surface

(2015) Toru Shinoe et al.   CURRENT OPINION IN NEUROBIOLOGY

MIM-Induced Membrane Bending Promotes Dendritic Spine Initiation

(2015) Juha Saarikangas et al.   DEVELOPMENTAL CELL

Actin Out: Regulation of the Synaptic Cytoskeleton

(2015) Erin F. Spence et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Shootin1–cortactin interaction mediates signal–force transduction for axon outgrowth

(2015) Yusuke Kubo et al.   JOURNAL OF CELL BIOLOGY

Mechanical coupling between transsynaptic N-cadherin adhesions and actin flow stabilizes dendritic spines

(2015) Anaël Chazeau et al.   MOLECULAR BIOLOGY OF THE CELL

Neurofilament subunits are integral components of synapses and modulate neurotransmission and behavior in vivo

(2015) A Yuan et al.   MOLECULAR PSYCHIATRY

Nanoscale segregation of actin nucleation and elongation factors determines dendritic spine protrusion

(2014) Anaël Chazeau et al.   EMBO JOURNAL

ProSAP1 and membrane nanodomain-associated syndapin I promote postsynapse formation and function

(2014) Katharina Schneider et al.   JOURNAL OF CELL BIOLOGY

Structural and Molecular Remodeling of Dendritic Spine Substructures during Long-Term Potentiation

(2014) Miquel Bosch et al.   NEURON

Dynamic Shaping of Cellular Membranes by Phospholipids and Membrane-Deforming Proteins

(2014) Shiro Suetsugu et al.   PHYSIOLOGICAL REVIEWS

Activity-Dependent Dendritic Spine Shrinkage and Growth Involve Downregulation of Cofilin via Distinct Mechanisms

(2014) Barbara Calabrese et al.   PLoS One

A Septin-Dependent Diffusion Barrier at Dendritic Spine Necks

(2014) Helge Ewers et al.   PLoS One

Extracellular matrix control of dendritic spine and synapse structure and plasticity in adulthood

(2014) Aaron D. Levy et al.   Frontiers in Neuroanatomy

Conversion of a Signal into Forces for Axon Outgrowth through Pak1-Mediated Shootin1 Phosphorylation

(2013) Michinori Toriyama et al.   CURRENT BIOLOGY

Disruption of Arp2/3 Results in Asymmetric Structural Plasticity of Dendritic Spines and Progressive Synaptic and Behavioral Abnormalities

(2013) I. H. Kim et al.   JOURNAL OF NEUROSCIENCE

Integrin  3 Is Required for Late Postnatal Stability of Dendrite Arbors, Dendritic Spines and Synapses, and Mouse Behavior

(2013) M. E. Kerrisk et al.   JOURNAL OF NEUROSCIENCE

Nonlinear Decoding and Asymmetric Representation of Neuronal Input Information by CaMKIIα and Calcineurin

(2013) Hajime Fujii et al.   Cell Reports

Inhibition of SRGAP2 Function by Its Human-Specific Paralogs Induces Neoteny during Spine Maturation

(2012) Cécile Charrier et al.   CELL

Srgap3−/− mice present a neurodevelopmental disorder with schizophrenia-related intermediate phenotypes

(2012) Robert Waltereit et al.   FASEB JOURNAL

Integrin  1 Signals through Arg to Regulate Postnatal Dendritic Arborization, Synapse Density, and Behavior

(2012) M. S. Warren et al.   JOURNAL OF NEUROSCIENCE

Polarization of actin cytoskeleton is reduced in dendritic protrusions during early spine development in hippocampal neuron

(2012) Vedakumar Tatavarty et al.   MOLECULAR BIOLOGY OF THE CELL

Septins: the fourth component of the cytoskeleton

(2012) Serge Mostowy et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Distinct Initial SNARE Configurations Underlying the Diversity of Exocytosis

(2012) Haruo Kasai et al.   PHYSIOLOGICAL REVIEWS

Cadherins in Brain Morphogenesis and Wiring

(2012) Shinji Hirano et al.   PHYSIOLOGICAL REVIEWS

Actin, Spectrin, and Associated Proteins Form a Periodic Cytoskeletal Structure in Axons

(2012) K. Xu et al.   SCIENCE

A Role for Septins in the Interaction between the Listeria monocytogenes Invasion Protein InlB and the Met Receptor

(2011) Serge Mostowy et al.   BIOPHYSICAL JOURNAL

Structural plasticity of dendritic spines

(2011) Miquel Bosch et al.   CURRENT OPINION IN NEUROBIOLOGY

Casting a net on dendritic spines: The extracellular matrix and its receptors

(2011) Lorraine E. Dansie et al.   Developmental Neurobiology

The F-BAR Protein Rapostlin Regulates Dendritic Spine Formation in Hippocampal Neurons

(2011) Yohei Wakita et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

WRP/srGAP3 Facilitates the Initiation of Spine Development by an Inverse F-BAR Domain, and Its Loss Impairs Long-Term Memory

(2011) B. R. Carlson et al.   JOURNAL OF NEUROSCIENCE

Local, persistent activation of Rho GTPases during plasticity of single dendritic spines

(2011) Hideji Murakoshi et al.   NATURE

Dynamics of the Rho-family small GTPases in actin regulation and motility

(2011) Désirée Spiering et al.   Cell Adhesion & Migration

Vasodilator-stimulated Phosphoprotein (VASP) Induces Actin Assembly in Dendritic Spines to Promote Their Development and Potentiate Synaptic Strength

(2010) Wan-Hsin Lin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

N-cadherin mediates plasticity-induced long-term spine stabilization

(2010) Pablo Mendez et al.   JOURNAL OF CELL BIOLOGY

Persistence of Coordinated Long-Term Potentiation and Dendritic Spine Enlargement at Mature Hippocampal CA1 Synapses Requires N-Cadherin

(2010) O. Bozdagi et al.   JOURNAL OF NEUROSCIENCE

Rapid spine stabilization and synaptic enhancement at the onset of behavioural learning

(2010) Todd F. Roberts et al.   NATURE

The dual role of the extracellular matrix in synaptic plasticity and homeostasis

(2010) Alexander Dityatev et al.   NATURE REVIEWS NEUROSCIENCE

SynCAM 1 Adhesion Dynamically Regulates Synapse Number and Impacts Plasticity and Learning

(2010) Elissa M. Robbins et al.   NEURON

Single-Molecule Discrimination of Discrete Perisynaptic and Distributed Sites of Actin Filament Assembly within Dendritic Spines

(2010) Nicholas A. Frost et al.   NEURON

Structural dynamics of dendritic spines in memory and cognition

(2010) Haruo Kasai et al.   TRENDS IN NEUROSCIENCES

The F-BAR Domain of srGAP2 Induces Membrane Protrusions Required for Neuronal Migration and Morphogenesis

(2009) Sabrice Guerrier et al.   CELL

Molecular Mechanisms of Membrane Deformation by I-BAR Domain Proteins

(2009) Juha Saarikangas et al.   CURRENT BIOLOGY

Dendritic spine formation and stabilization

(2009) Yoshihiro Yoshihara et al.   CURRENT OPINION IN NEUROBIOLOGY

Defining mechanisms of actin polymerization and depolymerization during dendritic spine morphogenesis

(2009) Pirta Hotulainen et al.   JOURNAL OF CELL BIOLOGY

Dynamic expression of the Slit-Robo GTPase activating protein genes during development of the murine nervous system

(2009) Claire Bacon et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Molecular Architecture of Synaptic Actin Cytoskeleton in Hippocampal Neurons Reveals a Mechanism of Dendritic Spine Morphogenesis

(2009) Farida Korobova et al.   MOLECULAR BIOLOGY OF THE CELL

Activation of CaMKII in single dendritic spines during long-term potentiation

(2009) Seok-Jin R. Lee et al.   NATURE

The trip of the tip: understanding the growth cone machinery

(2009) Laura Anne Lowery et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Experience-dependent structural synaptic plasticity in the mammalian brain

(2009) Anthony Holtmaat et al.   NATURE REVIEWS NEUROSCIENCE

Dynamic Microtubules Regulate Dendritic Spine Morphology and Synaptic Plasticity

(2009) Jacek Jaworski et al.   NEURON

Investigating Sub-Spine Actin Dynamics in Rat Hippocampal Neurons with Super-Resolution Optical Imaging

(2009) Vedakumar Tatavarty et al.   PLoS One

Membrane Fusion: Grappling with SNARE and SM Proteins

(2009) T. C. Sudhof et al.   SCIENCE

Multi-level molecular clutches in motile cell processes

(2009) Grégory Giannone et al.   TRENDS IN CELL BIOLOGY

Balancing Structure and Function at Hippocampal Dendritic Spines

(2008) Jennifer N Bourne et al.   Annual Review of Neuroscience

N-WASP and the Arp2/3 Complex Are Critical Regulators of Actin in the Development of Dendritic Spines and Synapses

(2008) Adam M. Wegner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Shootin1 interacts with actin retrograde flow and L1-CAM to promote axon outgrowth

(2008) Tadayuki Shimada et al.   JOURNAL OF CELL BIOLOGY

Activity-Dependent Dynamic Microtubule Invasion of Dendritic Spines

(2008) X. Hu et al.   JOURNAL OF NEUROSCIENCE

Microtubules in Dendritic Spine Development

(2008) J. Gu et al.   JOURNAL OF NEUROSCIENCE

Actin in action: the interplay between the actin cytoskeleton and synaptic efficacy

(2008) Lorenzo A. Cingolani et al.   NATURE REVIEWS NEUROSCIENCE

Activity-Dependent Synaptogenesis: Regulation by a CaM-Kinase Kinase/CaM-Kinase I/βPIX Signaling Complex

(2008) Takeo Saneyoshi et al.   NEURON

The Subspine Organization of Actin Fibers Regulates the Structure and Plasticity of Dendritic Spines

(2008) Naoki Honkura et al.   NEURON

Protein Synthesis and Neurotrophin-Dependent Structural Plasticity of Single Dendritic Spines

(2008) J.-i. Tanaka et al.   SCIENCE

Cadherins and catenins at synapses: roles in synaptogenesis and synaptic plasticity

(2008) Jyothi Arikkath et al.   TRENDS IN NEUROSCIENCES