Dendritic Spine Initiation in Brain Development, Learning and Diseases and Impact of BAR-Domain Proteins

The state of F-BAR domains as membrane-bound oligomeric platforms

(2021) Chloe E. Snider et al.   TRENDS IN CELL BIOLOGY

The WAVE complex associates with sites of saddle membrane curvature

(2021) Anne Pipathsouk et al.   JOURNAL OF CELL BIOLOGY

Distinct roles of srGAP3‐Rac1 in the initiation and maintenance phases of neuropathic pain induced by paclitaxel

(2020) Zihang Chen et al.   JOURNAL OF PHYSIOLOGY-LONDON

Light-Inducible Generation of Membrane Curvature in Live Cells with Engineered BAR Domain Proteins

(2020) Taylor Jones et al.   ACS Synthetic Biology

Sex differences in dendritic spine density and morphology in auditory and visual cortices in adolescence and adulthood

(2020) Emily M. Parker et al.   Scientific Reports

Sculpting Dendritic Spines during Initiation and Maintenance of Neuropathic Pain

(2020) Harrison J. Stratton et al.   JOURNAL OF NEUROSCIENCE

Thalamocortical Hyperconnectivity and Amygdala-Cortical Hypoconnectivity in Male Patients With Autism Spectrum Disorder

(2019) Tetsuya Iidaka et al.   Frontiers in Psychiatry

Curving Cells Inside and Out: Roles of BAR Domain Proteins in Membrane Shaping and Its Cellular Implications

(2019) Mijo Simunovic et al.   Annual Review of Cell and Developmental Biology

Plasticity of dendritic spines: Molecular function and dysfunction in neurodevelopmental disorders

(2019) Jun Nishiyama   PSYCHIATRY AND CLINICAL NEUROSCIENCES

Exercise-induced enhancement of synaptic function triggered by the inverse BAR protein, Mtss1L

(2019) Christina Chatzi et al.   eLife

Phagocytosis is mediated by two-dimensional assemblies of the F-BAR protein GAS7

(2019) Kyoko Hanawa-Suetsugu et al.   Nature Communications

MIM-Deficient Mice Exhibit Anatomical Changes in Dendritic Spines, Cortex Volume and Brain Ventricles, and Functional Changes in Motor Coordination and Learning

(2019) Rimante Minkeviciene et al.   Frontiers in Molecular Neuroscience

A curvature-dependent membrane binding by tyrosine kinase Fer involves an intrinsically disordered region

(2018) Hikaru Yamamoto et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Membrane re-modelling by BAR domain superfamily proteins via molecular and non-molecular factors

(2018) Tamako Nishimura et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Regulation of actin dynamics during structural plasticity of dendritic spines: Signaling messengers and actin-binding proteins

(2018) Jelena Borovac et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Preferential stabilization of newly formed dendritic spines in motor cortex during manual skill learning predicts performance gains, but not memory endurance

(2018) Taylor A. Clark et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Etiology and Pharmacology of Neuropathic Pain

(2018) Sascha R. A. Alles et al.   PHARMACOLOGICAL REVIEWS

Interregional synaptic maps among engram cells underlie memory formation

(2018) Jun-Hyeok Choi et al.   SCIENCE

Synapse-specific representation of the identity of overlapping memory engrams

(2018) Kareem Abdou et al.   SCIENCE

Hotspots of dendritic spine turnover facilitate clustered spine addition and learning and memory

(2018) Adam C. Frank et al.   Nature Communications

MTSS1 Regulation of Actin-Nucleating Formin DAAM1 in Dendritic Filopodia Determines Final Dendritic Configuration of Purkinje Cells

(2018) Kelly Kawabata Galbraith et al.   Cell Reports

Children with ASD show links between aberrant sound processing, social symptoms, and atypical auditory interhemispheric and thalamocortical functional connectivity

(2018) Annika C. Linke et al.   Developmental Cognitive Neuroscience

Chronic 2P-STED imaging reveals high turnover of dendritic spines in the hippocampus in vivo

(2018) Thomas Pfeiffer et al.   eLife

ASD-Associated De Novo Mutations in Five Actin Regulators Show Both Shared and Distinct Defects in Dendritic Spines and Inhibitory Synapses in Cultured Hippocampal Neurons

(2018) Iryna Hlushchenko et al.   Frontiers in Cellular Neuroscience

Molecular Mechanisms of the Memory Trace

(2018) Arun Asok et al.   TRENDS IN NEUROSCIENCES

Protracted dendritic growth in the typically developing human amygdala and increased spine density in young ASD brains

(2017) R.K. Weir et al.   JOURNAL OF COMPARATIVE NEUROLOGY

A dual role for the RhoGEF Ephexin5 in regulation of dendritic spine outgrowth

(2017) A.M. Hamilton et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Dendritic spine dysgenesis in superficial dorsal horn sensory neurons after spinal cord injury

(2017) Xiaoyu C Cao et al.   Molecular Pain

Spine Dynamics: Are They All the Same?

(2017) Kalen P. Berry et al.   NEURON

Engrams and circuits crucial for systems consolidation of a memory

(2017) Takashi Kitamura et al.   SCIENCE

Dendritic Spine Pathology in Neurodegenerative Diseases

(2016) Jochen Herms et al.   Annual Review of Pathology-Mechanisms of Disease

Linking up at the BAR: Oligomerization and F-BAR protein function

(2016) Nathan A. McDonald et al.   CELL CYCLE

ARHGAP4 mutated in a Chinese intellectually challenged family

(2016) Fuhua Liu et al.   GENE

The Arp2/3 Complex Is Essential for Distinct Stages of Spine Synapse Maturation, Including Synapse Unsilencing

(2016) E. F. Spence et al.   JOURNAL OF NEUROSCIENCE

SRGAP2 and Its Human-Specific Paralog Co-Regulate the Development of Excitatory and Inhibitory Synapses

(2016) Matteo Fossati et al.   NEURON

IRSp53/BAIAP2 in dendritic spine development, NMDA receptor regulation, and psychiatric disorders

(2016) Jaeseung Kang et al.   NEUROPHARMACOLOGY

Coordinated autoinhibition of F-BAR domain membrane binding and WASp activation by Nervous Wreck

(2016) Tatiana B. Stanishneva-Konovalova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Growth arrest specific gene 7 is associated with schizophrenia and regulates neuronal migration and morphogenesis

(2016) Zhengrong Zhang et al.   Molecular Brain

Oligomerization but Not Membrane Bending Underlies the Function of Certain F-BAR Proteins in Cell Motility and Cytokinesis

(2015) Nathan A. McDonald et al.   DEVELOPMENTAL CELL

MIM-Induced Membrane Bending Promotes Dendritic Spine Initiation

(2015) Juha Saarikangas et al.   DEVELOPMENTAL CELL

Different functional modes of BAR domain proteins in formation and plasticity of mammalian postsynapses

(2015) M. M. Kessels et al.   JOURNAL OF CELL SCIENCE

Labelling and optical erasure of synaptic memory traces in the motor cortex

(2015) Akiko Hayashi-Takagi et al.   NATURE

Subtype-specific plasticity of inhibitory circuits in motor cortex during motor learning

(2015) Simon X Chen et al.   NATURE NEUROSCIENCE

Membrane Charge Directs the Outcome of F-BAR Domain Lipid Binding and Autoregulation

(2015) Charlotte F. Kelley et al.   Cell Reports

The Molecular and Systems Biology of Memory

(2014) Eric R. Kandel et al.   CELL

The WAVE Regulatory Complex Links Diverse Receptors to the Actin Cytoskeleton

(2014) Baoyu Chen et al.   CELL

ProSAP1 and membrane nanodomain-associated syndapin I promote postsynapse formation and function

(2014) Katharina Schneider et al.   JOURNAL OF CELL BIOLOGY

De novo mutations in schizophrenia implicate synaptic networks

(2014) Menachem Fromer et al.   NATURE

A polygenic burden of rare disruptive mutations in schizophrenia

(2014) Shaun M. Purcell et al.   NATURE

Mechanism of IRSp53 inhibition and combinatorial activation by Cdc42 and downstream effectors

(2014) David J Kast et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Loss of mTOR-Dependent Macroautophagy Causes Autistic-like Synaptic Pruning Deficits

(2014) Guomei Tang et al.   NEURON

Dynamic Shaping of Cellular Membranes by Phospholipids and Membrane-Deforming Proteins

(2014) Shiro Suetsugu et al.   PHYSIOLOGICAL REVIEWS

BAIAP2 exhibits association to childhood ADHD especially predominantly inattentive subtype in Chinese Han subjects

(2013) Lu Liu et al.   Behavioral and Brain Functions

Alterations of dendritic protrusions over the first postnatal year of a mouse: an analysis in layer VI of the barrel cortex

(2013) David A. Orner et al.   Brain Structure & Function

Burn injury-induced mechanical allodynia is maintained by Rac1-regulated dendritic spine dysgenesis

(2013) Andrew M. Tan et al.   EXPERIMENTAL NEUROLOGY

Developmental vulnerability of synapses and circuits associated with neuropsychiatric disorders

(2013) Peter Penzes et al.   JOURNAL OF NEUROCHEMISTRY

srGAP1 regulates lamellipodial dynamics and cell migratory behavior by modulating Rac1 activity

(2013) Daisuke Yamazaki et al.   MOLECULAR BIOLOGY OF THE CELL

Brain Hyperconnectivity in Children with Autism and its Links to Social Deficits

(2013) Kaustubh Supekar et al.   Cell Reports

Membrane-Sculpting BAR Domains Generate Stable Lipid Microdomains

(2013) Hongxia Zhao et al.   Cell Reports

Epidemiology of Alzheimer Disease

(2013) R. Mayeux et al.   Cold Spring Harbor Perspectives in Medicine

A novel contiguous gene deletion ofAVPR2andARHGAP4genes in male dizygotic twins with nephrogenic diabetes insipidus and intellectual disability

(2012) Lingli Huang et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Evolution of Human-Specific Neural SRGAP2 Genes by Incomplete Segmental Duplication

(2012) Megan Y. Dennis et al.   CELL

Srgap3−/− mice present a neurodevelopmental disorder with schizophrenia-related intermediate phenotypes

(2012) Robert Waltereit et al.   FASEB JOURNAL

Functional connectivity for an “Island of sparing” in autism spectrum disorder: An fMRI study of visual search

(2012) Brandon Keehn et al.   HUMAN BRAIN MAPPING

Alzheimer's disease-related protein hGas7b interferes with kinesin motility

(2012) M. Hidaka et al.   JOURNAL OF BIOCHEMISTRY

The F-BAR domains from srGAP1, srGAP2 and srGAP3 regulate membrane deformation differently

(2012) J. Coutinho-Budd et al.   JOURNAL OF CELL SCIENCE

Maladaptive Dendritic Spine Remodeling Contributes to Diabetic Neuropathic Pain

(2012) A. M. Tan et al.   JOURNAL OF NEUROSCIENCE

Adaptor Protein APPL1 Couples Synaptic NMDA Receptor with Neuronal Prosurvival Phosphatidylinositol 3-Kinase/Akt Pathway

(2012) Y.-b. Wang et al.   JOURNAL OF NEUROSCIENCE

The cellular function of srGAP3 and its role in neuronal morphogenesis

(2012) Claire Bacon et al.   MECHANISMS OF DEVELOPMENT

Repetitive motor learning induces coordinated formation of clustered dendritic spines in vivo

(2012) Min Fu et al.   NATURE

Activity-Dependent Growth of New Dendritic Spines Is Regulated by the Proteasome

(2012) Andrew M. Hamilton et al.   NEURON

Dendritic spine pathology in schizophrenia

(2012) J.R. Glausier et al.   NEUROSCIENCE

Morphological and Behavioral Changes in the Pathogenesis of a Novel Mouse Model of Communicating Hydrocephalus

(2012) Allison B. McMullen et al.   PLoS One

UNC-40/DCC, SAX-3/Robo, and VAB-1/Eph Polarize F-Actin during Embryonic Morphogenesis by Regulating the WAVE/SCAR Actin Nucleation Complex

(2012) Yelena Y. Bernadskaya et al.   PLoS Genetics

Early infantile epileptic encephalopathy associated with the disrupted gene encoding Slit-Robo Rho GTPase activating protein 2 (SRGAP2)

(2011) Hirotomo Saitsu et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Membrane shaping by the Bin/amphiphysin/Rvs (BAR) domain protein superfamily

(2011) Yijian Rao et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The Mental Retardation Associated Protein, srGAP3 Negatively Regulates VPA-Induced Neuronal Differentiation of Neuro2A Cells

(2011) Keng Chen et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Rac1-regulated dendritic spine remodeling contributes to neuropathic pain after peripheral nerve injury

(2011) Andrew M. Tan et al.   EXPERIMENTAL NEUROLOGY

Spinal cord injury, dendritic spine remodeling, and spinal memory mechanisms

(2011) Andrew M. Tan et al.   EXPERIMENTAL NEUROLOGY

Use of array CGH to detect exonic copy number variants throughout the genome in autism families detects a novel deletion in TMLHE

(2011) Patricia B.S. Celestino-Soper et al.   HUMAN MOLECULAR GENETICS

SrGAP3 interacts with lamellipodin at the cell membrane and regulates Rac-dependent cellular protrusions

(2011) V. Endris et al.   JOURNAL OF CELL SCIENCE

WRP/srGAP3 Facilitates the Initiation of Spine Development by an Inverse F-BAR Domain, and Its Loss Impairs Long-Term Memory

(2011) B. R. Carlson et al.   JOURNAL OF NEUROSCIENCE

Alzheimer's disease

(2011) Clive Ballard et al.   LANCET

Local, persistent activation of Rho GTPases during plasticity of single dendritic spines

(2011) Hideji Murakoshi et al.   NATURE

Dendritic spine pathology in neuropsychiatric disorders

(2011) Peter Penzes et al.   NATURE NEUROSCIENCE

Rare De Novo and Transmitted Copy-Number Variation in Autistic Spectrum Disorders

(2011) Dan Levy et al.   NEURON

A new definition of neuropathic pain

(2011) Troels S. Jensen et al.   PAIN

Spine growth in the anterior cingulate cortex is necessary for the consolidation of contextual fear memory

(2011) G. Vetere et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Early Tagging of Cortical Networks Is Required for the Formation of Enduring Associative Memory

(2011) E. Lesburgueres et al.   SCIENCE

The Postsynaptic Organization of Synapses

(2011) M. Sheng et al.   Cold Spring Harbor Perspectives in Biology

Physical Mechanisms of Signal Integration by WASP Family Proteins

(2010) Shae B. Padrick et al.   Annual Review of Biochemistry

EphB-Mediated Degradation of the RhoA GEF Ephexin5 Relieves a Developmental Brake on Excitatory Synapse Formation

(2010) Seth S. Margolis et al.   CELL

Dendritic spine abnormalities in mental retardation

(2010) Oliver von Bohlen und Halbach   CELL AND TISSUE RESEARCH

Synapse Pathology in Psychiatric and Neurologic Disease

(2010) Myrrhe van Spronsen et al.   Current Neurology and Neuroscience Reports

New mechanisms and functions of actin nucleation

(2010) Elif Nur Firat-Karalar et al.   CURRENT OPINION IN CELL BIOLOGY

Gas7 Functions with N-WASP to Regulate the Neurite Outgrowth of Hippocampal Neurons

(2010) Jhong-Jhe You et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Actin in dendritic spines: connecting dynamics to function

(2010) Pirta Hotulainen et al.   JOURNAL OF CELL BIOLOGY

Association study of six candidate genes asymmetrically expressed in the two cerebral hemispheres suggests the involvement of BAIAP2 in autism

(2010) Claudio Toma et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Structure and control of the actin regulatory WAVE complex

(2010) Zhucheng Chen et al.   NATURE

Rapid spine stabilization and synaptic enhancement at the onset of behavioural learning

(2010) Todd F. Roberts et al.   NATURE

Molecular basis for SH3 domain regulation of F-BAR-mediated membrane deformation

(2010) Y. Rao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Self-Assembly of Filopodia-Like Structures on Supported Lipid Bilayers

(2010) Kwonmoo Lee et al.   SCIENCE

Key role for gene dosage and synaptic homeostasis in autism spectrum disorders

(2010) Roberto Toro et al.   TRENDS IN GENETICS

Case-Control Study of Six Genes Asymmetrically Expressed in the Two Cerebral Hemispheres: Association of BAIAP2 with Attention-Deficit/Hyperactivity Disorder

(2009) Marta Ribasés et al.   BIOLOGICAL PSYCHIATRY

Increased dendritic spine densities on cortical projection neurons in autism spectrum disorders

(2009) Jeffrey J. Hutsler et al.   BRAIN RESEARCH

The F-BAR Domain of srGAP2 Induces Membrane Protrusions Required for Neuronal Migration and Morphogenesis

(2009) Sabrice Guerrier et al.   CELL

The BAR Domain Superfamily: Membrane-Molding Macromolecules

(2009) Adam Frost et al.   CELL

Molecular Mechanisms of Membrane Deformation by I-BAR Domain Proteins

(2009) Juha Saarikangas et al.   CURRENT BIOLOGY

A Novel Role for hGas7b in Microtubular Maintenance

(2009) Hirotada Akiyama et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Toca-1-N-WASP Complex Links Filopodial Formation to Endocytosis

(2009) Wenyu Bu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Defining mechanisms of actin polymerization and depolymerization during dendritic spine morphogenesis

(2009) Pirta Hotulainen et al.   JOURNAL OF CELL BIOLOGY

Dynamic expression of the Slit-Robo GTPase activating protein genes during development of the murine nervous system

(2009) Claire Bacon et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Activation of the WAVE Complex by Coincident Signals Controls Actin Assembly

(2009) Andres M. Lebensohn et al.   MOLECULAR CELL

Rapid formation and selective stabilization of synapses for enduring motor memories

(2009) Tonghui Xu et al.   NATURE

Stably maintained dendritic spines are associated with lifelong memories

(2009) Guang Yang et al.   NATURE

What does the retrosplenial cortex do?

(2009) Seralynne D. Vann et al.   NATURE REVIEWS NEUROSCIENCE

The Tyrosine Kinase Fer Is a Downstream Target of the PLD-PA Pathway that Regulates Cell Migration

(2009) T. Itoh et al.   Science Signaling

Structural Basis of Membrane Invagination by F-BAR Domains

(2008) Adam Frost et al.   CELL

Synaptic clustering by dendritic signalling mechanisms

(2008) Matthew E Larkum et al.   CURRENT OPINION IN NEUROBIOLOGY

EFC/F-BAR proteins and the N-WASP–WIP complex induce membrane curvature-dependent actin polymerization

(2008) Kazunari Takano et al.   EMBO JOURNAL

Transient Spine Expansion and Learning-Induced Plasticity in Layer 1 Primary Motor Cortex

(2008) K. J. Harms et al.   JOURNAL OF NEUROSCIENCE

Hierarchical Regulation of WASP/WAVE Proteins

(2008) Shae B. Padrick et al.   MOLECULAR CELL

Dendritic Spine Loss and Synaptic Alterations in Alzheimer’s Disease

(2008) Marlen Knobloch et al.   MOLECULAR NEUROBIOLOGY

Membrane-induced bundling of actin filaments

(2008) Allen P. Liu et al.   Nature Physics

Reduced Dendritic Spine Density in Auditory Cortex of Subjects with Schizophrenia

(2008) Robert A Sweet et al.   NEUROPSYCHOPHARMACOLOGY

The Spread of Ras Activity Triggered by Activation of a Single Dendritic Spine

(2008) C. D. Harvey et al.   SCIENCE