Time Resolved‐Fluorescence Resonance Energy Transfer platform for quantitative nucleosome binding and footprinting

DOT1L activity in leukemia cells requires interaction with ubiquitylated H2B that promotes productive nucleosome binding

(2022) Cathy J. Spangler et al.   Cell Reports

Principles of nucleosome recognition by chromatin factors and enzymes

(2021) Robert K. McGinty et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Crystal Structure of the LSD1/CoREST Histone Demethylase Bound to Its Nucleosome Substrate

(2020) Sang-Ah Kim et al.   MOLECULAR CELL

RYBP/YAF2-PRC1 complexes and histone H1-dependent chromatin compaction mediate propagation of H2AK119ub1 during cell division

(2020) Jicheng Zhao et al.   NATURE CELL BIOLOGY

The roles of histone variants in fine-tuning chromatin organization and function

(2020) Sara Martire et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Comprehensive nucleosome interactome screen establishes fundamental principles of nucleosome binding

(2020) Aleksandra Skrajna et al.   NUCLEIC ACIDS RESEARCH

Structural Basis for Recognition of Ubiquitylated Nucleosome by Dot1L Methyltransferase

(2019) Cathy J. Anderson et al.   Cell Reports

A General TR-FRET Assay Platform for High-Throughput Screening and Characterizing Inhibitors of Methyl-Lysine Reader Proteins

(2019) Justin M. Rectenwald et al.   SLAS Discovery

Canonical PRC1 controls sequence-independent propagation of Polycomb-mediated gene silencing

(2019) Hagar F. Moussa et al.   Nature Communications

Developmental disorders with intellectual disability driven by chromatin dysregulation: Clinical overlaps and molecular mechanisms

(2018) L. Larizza et al.   CLINICAL GENETICS

Oncohistones: drivers of pediatric cancers

(2017) Faizaan Mohammad et al.   GENES & DEVELOPMENT

Arginine Methylation: The Coming of Age

(2017) Roméo S. Blanc et al.   MOLECULAR CELL

Proteome-wide analysis of arginine monomethylation reveals widespread occurrence in human cells

(2016) Sara C. Larsen et al.   Science Signaling

Epigenetics and Human Disease

(2016) Huda Y. Zoghbi et al.   Cold Spring Harbor Perspectives in Biology

RYBP stimulates PRC1 to shape chromatin-based communication between Polycomb repressive complexes

(2016) Nathan R Rose et al.   eLife

Proteome-wide analysis of arginine monomethylation reveals widespread occurrence in human cells

(2016) Sara C. Larsen et al.   Science Signaling

Extranucleosomal DNA enhances the activity of the LSD1/CoREST histone demethylase complex

(2015) Sang-Ah Kim et al.   NUCLEIC ACIDS RESEARCH

A method for evaluating nucleosome stability with a protein-binding fluorescent dye

(2014) Hiroyuki Taguchi et al.   METHODS

Crystal structure of the PRC1 ubiquitylation module bound to the nucleosome

(2014) Robert K. McGinty et al.   NATURE

Discovery and saturation analysis of cancer genes across 21 tumour types

(2014) Michael S. Lawrence et al.   NATURE

Nucleosomal regulation of chromatin composition and nuclear assembly revealed by histone depletion

(2014) Christian Zierhut et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

PRC1 complex diversity: where is it taking us?

(2014) Jesús Gil et al.   TRENDS IN CELL BIOLOGY

Mutational landscape and significance across 12 major cancer types

(2013) Cyriac Kandoth et al.   NATURE

DNA Methylation and Its Basic Function

(2012) Lisa D Moore et al.   NEUROPSYCHOPHARMACOLOGY

Regulation of chromatin by histone modifications

(2011) Andrew J Bannister et al.   CELL RESEARCH

RCC1 Uses a Conformationally Diverse Loop Region to Interact with the Nucleosome: A Model for the RCC1–Nucleosome Complex

(2010) Joseph R. England et al.   JOURNAL OF MOLECULAR BIOLOGY

Crystal Structures of Nucleosome Core Particles Containing the ‘601’ Strong Positioning Sequence

(2010) Dileep Vasudevan et al.   JOURNAL OF MOLECULAR BIOLOGY

Structure of RCC1 chromatin factor bound to the nucleosome core particle

(2010) Ravindra D. Makde et al.   NATURE

Genome-Wide Analysis of Histidine Repeats Reveals Their Role in the Localization of Human Proteins to the Nuclear Speckles Compartment

(2009) Eulàlia Salichs et al.   PLoS Genetics

Spatial and temporal coordination of mitosis by Ran GTPase

(2008) Paul R. Clarke et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The effect of H3K79 dimethylation and H4K20 trimethylation on nucleosome and chromatin structure

(2008) Xu Lu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY