RYBP stimulates PRC1 to shape chromatin-based communication between Polycomb repressive complexes

Super-resolution imaging reveals distinct chromatin folding for different epigenetic states

(2016) Alistair N. Boettiger et al.   NATURE

The dynamic interactome and genomic targets of Polycomb complexes during stem-cell differentiation

(2016) Susan L Kloet et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

deepTools2: a next generation web server for deep-sequencing data analysis

(2016) Fidel Ramírez et al.   NUCLEIC ACIDS RESEARCH

Chromatin topology is coupled to Polycomb group protein subnuclear organization

(2016) Ajazul H. Wani et al.   Nature Communications

The dynamic interactome and genomic targets of Polycomb complexes during stem-cell differentiation

(2016) Susan L Kloet et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

YAF2 promotes TP53-mediated genotoxic stress response via stabilization of PDCD5

(2015) Soo-Yeon Park et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The E3 ubiquitin ligase activity of RING1B is not essential for early mouse development

(2015) Robert S. Illingworth et al.   GENES & DEVELOPMENT

Transcriptional repression by PRC1 in the absence of H2A monoubiquitylation

(2015) Ana Raquel Pengelly et al.   GENES & DEVELOPMENT

Genome-wide activities of Polycomb complexes control pervasive transcription

(2015) Hun-Goo Lee et al.   GENOME RESEARCH

Role of Polycomb RYBP in Maintaining the B-1-to-B-2 B-Cell Lineage Switch in Adult Hematopoiesis

(2015) Carmela Calés et al.   MOLECULAR AND CELLULAR BIOLOGY

Calibrating ChIP-Seq with Nucleosomal Internal Standards to Measure Histone Modification Density Genome Wide

(2015) Adrian T. Grzybowski et al.   MOLECULAR CELL

FBXL10 protects Polycomb-bound genes from hypermethylation

(2015) Mathieu Boulard et al.   NATURE GENETICS

Polycomb repressive complex PRC1 spatially constrains the mouse embryonic stem cell genome

(2015) Stefan Schoenfelder et al.   NATURE GENETICS

Targeting Polycomb systems to regulate gene expression: modifications to a complex story

(2015) Neil P. Blackledge et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Biological chromodynamics: a general method for measuring protein occupancy across the genome by calibrating ChIP-seq

(2015) Bin Hu et al.   NUCLEIC ACIDS RESEARCH

Structural basis of histone H3K27 trimethylation by an active polycomb repressive complex 2

(2015) L. Jiao et al.   SCIENCE

BMI1–RING1B is an autoinhibited RING E3 ubiquitin ligase

(2015) Asad M. Taherbhoy et al.   Nature Communications

Variant PRC1 Complex-Dependent H2A Ubiquitylation Drives PRC2 Recruitment and Polycomb Domain Formation

(2014) Neil P. Blackledge et al.   CELL

The controversial role of the Polycomb group proteins in transcription and cancer: how much do we not understand Polycomb proteins?

(2014) Andrea Scelfo et al.   FEBS Journal

Quantifying ChIP-seq data: a spiking method providing an internal reference for sample-to-sample normalization

(2014) N. Bonhoure et al.   GENOME RESEARCH

Gene Silencing Triggers Polycomb Repressive Complex 2 Recruitment to CpG Islands Genome Wide

(2014) Eva Madi Riising et al.   MOLECULAR CELL

What are memories made of? How Polycomb and Trithorax proteins mediate epigenetic memory

(2014) Philipp A. Steffen et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Histone H2A monoubiquitination promotes histone H3 methylation in Polycomb repression

(2014) Reinhard Kalb et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

dRYBP Counteracts Chromatin-Dependent Activation and Repression of Transcription

(2014) Sol Fereres et al.   PLoS One

Quantitative ChIP-Seq Normalization Reveals Global Modulation of the Epigenome

(2014) David A. Orlando et al.   Cell Reports

Targeting Polycomb to Pericentric Heterochromatin in Embryonic Stem Cells Reveals a Role for H2AK119u1 in PRC2 Recruitment

(2014) Sarah Cooper et al.   Cell Reports

Dynamic Chromatin Remodeling Mediated by Polycomb Proteins Orchestrates Pancreatic Differentiation of Human Embryonic Stem Cells

(2013) Ruiyu Xie et al.   Cell Stem Cell

SAM Domain Polymerization Links Subnuclear Clustering of PRC1 to Gene Silencing

(2013) Kyoichi Isono et al.   DEVELOPMENTAL CELL

A double take on bivalent promoters

(2013) P. Voigt et al.   GENES & DEVELOPMENT

Occupying Chromatin: Polycomb Mechanisms for Getting to Genomic Targets, Stopping Transcriptional Traffic, and Staying Put

(2013) Jeffrey A. Simon et al.   MOLECULAR CELL

Fbxl10/Kdm2b Recruits Polycomb Repressive Complex 1 to CpG Islands and Regulates H2A Ubiquitylation

(2013) Xudong Wu et al.   MOLECULAR CELL

Kdm2b maintains murine embryonic stem cell status by recruiting PRC1 complex to CpG islands of developmental genes

(2013) Jin He et al.   NATURE CELL BIOLOGY

Lysine-specific chemical cross-linking of protein complexes and identification of cross-linking sites using LC-MS/MS and the xQuest/xProphet software pipeline

(2013) Alexander Leitner et al.   Nature Protocols

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

A new world of Polycombs: unexpected partnerships and emerging functions

(2013) Yuri B. Schwartz et al.   NATURE REVIEWS GENETICS

Chromatin Sampling—An Emerging Perspective on Targeting Polycomb Repressor Proteins

(2013) Robert J. Klose et al.   PLoS Genetics

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

RYBP-PRC1 Complexes Mediate H2A Ubiquitylation at Polycomb Target Sites Independently of PRC2 and H3K27me3

(2012) Lígia Tavares et al.   CELL

Polycomb Associates Genome-wide with a Specific RNA Polymerase II Variant, and Regulates Metabolic Genes in ESCs

(2012) Emily Brookes et al.   Cell Stem Cell

In vivo Polycomb kinetics and mitotic chromatin binding distinguish stem cells from differentiated cells

(2012) J. P. Fonseca et al.   GENES & DEVELOPMENT

Modeling of epigenome dynamics identifies transcription factors that mediate Polycomb targeting

(2012) P. Arnold et al.   GENOME RESEARCH

DANPOS: Dynamic analysis of nucleosome position and occupancy by sequencing

(2012) K. Chen et al.   GENOME RESEARCH

RYBP Represses Endogenous Retroviruses and Preimplantation- and Germ Line-Specific Genes in Mouse Embryonic Stem Cells

(2012) K. Hisada et al.   MOLECULAR AND CELLULAR BIOLOGY

PCGF Homologs, CBX Proteins, and RYBP Define Functionally Distinct PRC1 Family Complexes

(2012) Zhonghua Gao et al.   MOLECULAR CELL

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

RYBP and Cbx7 Define Specific Biological Functions of Polycomb Complexes in Mouse Embryonic Stem Cells

(2012) Lluis Morey et al.   Cell Reports

Molecular architecture of human polycomb repressive complex 2

(2012) Claudio Ciferri et al.   eLife

KDM2B links the Polycomb Repressive Complex 1 (PRC1) to recognition of CpG islands

(2012) Anca M Farcas et al.   eLife

Renal Cyst Formation in Fh1-Deficient Mice Is Independent of the Hif/Phd Pathway: Roles for Fumarate in KEAP1 Succination and Nrf2 Signaling

(2011) Julie Adam et al.   CANCER CELL

Regulation of chromatin by histone modifications

(2011) Andrew J Bannister et al.   CELL RESEARCH

Compaction of chromatin by diverse Polycomb group proteins requires localized regions of high charge

(2011) D. J. Grau et al.   GENES & DEVELOPMENT

CpG islands and the regulation of transcription

(2011) A. M. Deaton et al.   GENES & DEVELOPMENT

The Polycomb complex PRC2 and its mark in life

(2011) Raphaël Margueron et al.   NATURE

MultiBac: expanding the research toolbox for multiprotein complexes

(2011) Christoph Bieniossek et al.   TRENDS IN BIOCHEMICAL SCIENCES

Ring1B Compacts Chromatin Structure and Represses Gene Expression Independent of Histone Ubiquitination

(2010) Ragnhild Eskeland et al.   MOLECULAR CELL

Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities

(2010) Sven Heinz et al.   MOLECULAR CELL

Polycomb Group Targeting through Different Binding Partners of RING1B C-Terminal Domain

(2010) Renjing Wang et al.   STRUCTURE

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

Biochemical mechanisms of gene regulation by polycomb group protein complexes

(2009) Jürg Müller et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Role of the polycomb protein EED in the propagation of repressive histone marks

(2009) Raphael Margueron et al.   NATURE

BioVenn – a web application for the comparison and visualization of biological lists using area-proportional Venn diagrams

(2008) Tim Hulsen et al.   BMC GENOMICS

Polycomb group proteins Ring1A/B are functionally linked to the core transcriptional regulatory circuitry to maintain ES cell identity

(2008) M. Endoh et al.   DEVELOPMENT

Polycomb Group Proteins Ezh2 and Rnf2 Direct Genomic Contraction and Imprinted Repression in Early Mouse Embryos

(2008) Rémi Terranova et al.   DEVELOPMENTAL CELL

dKDM2 couples histone H2A ubiquitylation to histone H3 demethylation during Polycomb group silencing

(2008) A. Lagarou et al.   GENES & DEVELOPMENT

Functional Characterization of the dRYBP Gene in Drosophila

(2008) I. Gonzalez et al.   GENETICS

Genomewide Analysis of PRC1 and PRC2 Occupancy Identifies Two Classes of Bivalent Domains

(2008) Manching Ku et al.   PLoS Genetics

Model-based Analysis of ChIP-Seq (MACS)

(2008) Yong Zhang et al.   GENOME BIOLOGY