Self-Immolative Hydroxybenzylamine Linkers for Traceless Protein Modification

A charge-maintaining ATRP initiator rescues the lost function of negatively charged protein-polymer conjugates

(2019) Stefanie L Baker et al.   BIOMACROMOLECULES

Site-Specific Conjugation of Polymers to Proteins

(2018) Yanjing Wang et al.   BIOMACROMOLECULES

Impact of Polymer Bioconjugation on Protein Stability and Activity Investigated with Discrete Conjugates: Alternatives to PEGylation

(2018) Josefine Morgenstern et al.   BIOMACROMOLECULES

Global profiling of lysine reactivity and ligandability in the human proteome

(2017) Stephan M. Hacker et al.   Nature Chemistry

Selective N-terminal functionalization of native peptides and proteins

(2017) Diao Chen et al.   Chemical Science

Investigating the Impact of Polymer Functional Groups on the Stability and Activity of Lysozyme–Polymer Conjugates

(2016) Melissa Lucius et al.   BIOMACROMOLECULES

Targeted drug delivery through the traceless release of tertiary and heteroaryl amines from antibody–drug conjugates

(2016) Leanna R. Staben et al.   Nature Chemistry

Click and chemically triggered declick reactions through reversible amine and thiol coupling via a conjugate acceptor

(2016) Katharine L. Diehl et al.   Nature Chemistry

Bioconjugation – using selective chemistry to enhance the properties of proteins and peptides as therapeutics and carriers

(2016) Smita B. Gunnoo et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Self-Immolative Spacers: Kinetic Aspects, Structure-Property Relationships, and Applications

(2015) Ahmed Alouane et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Releasable Conjugation of Polymers to Proteins

(2015) Yuhui Gong et al.   BIOCONJUGATE CHEMISTRY

Role of Polymer Architecture on the Activity of Polymer–Protein Conjugates for the Treatment of Accelerated Bone Loss Disorders

(2015) Bryan S. Tucker et al.   BIOMACROMOLECULES

Therapeutic Protein–Polymer Conjugates: Advancing Beyond PEGylation

(2014) Emma M. Pelegri-O’Day et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Aniline-Catalyzed Reductive Amination as a Powerful Method for the Preparation of Reducing End-“Clickable” Chitooligosaccharides

(2013) Alexandre Guerry et al.   BIOCONJUGATE CHEMISTRY

Sustained gastrointestinal activity of dendronized polymer–enzyme conjugates

(2013) Gregor Fuhrmann et al.   Nature Chemistry

A Self-Immolative Spacer That Enables Tunable Controlled Release of Phenols under Neutral Conditions

(2012) Kyle M. Schmid et al.   JOURNAL OF ORGANIC CHEMISTRY

Controlled Depolymerization: Stimuli-Responsive Self-Immolative Polymers

(2012) Gregory I. Peterson et al.   MACROMOLECULES

Development of the Carboxamide Protecting Group, 4-(tert-Butyldimethylsiloxy)-2-methoxybenzyl

(2011) Kazuhiro Muranaka et al.   JOURNAL OF ORGANIC CHEMISTRY

Benzaldehyde-Functionalized Polymer Vesicles

(2009) Guorong Sun et al.   ACS Nano

End-Functionalized Phosphorylcholine Methacrylates and their Use in Protein Conjugation

(2008) Debasis Samanta et al.   BIOMACROMOLECULES

The azaquinone-methide elimination: comparison study of 1,6- and 1,4-eliminations under physiological conditions

(2008) Rotem Erez et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Disulfide bridge based PEGylation of proteins

(2007) Steve Brocchini et al.   ADVANCED DRUG DELIVERY REVIEWS