标题
Global profiling of lysine reactivity and ligandability in the human proteome
作者
关键词
-
出版物
Nature Chemistry
Volume 9, Issue 12, Pages 1181-1190
出版商
Springer Nature
发表日期
2017-07-31
DOI
10.1038/nchem.2826
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Broad-Spectrum Kinase Profiling in Live Cells with Lysine-Targeted Sulfonyl Fluoride Probes
- (2017) Qian Zhao et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- AutoSite: an automated approach for pseudo-ligands prediction—from ligand-binding sites identification to predicting key ligand atoms
- (2016) Pradeep Anand Ravindranath et al. BIOINFORMATICS
- Iminoboronate-Based Peptide Cyclization That Responds to pH, Oxidation, and Small Molecule Modulators
- (2016) Anupam Bandyopadhyay et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- A tyrosine-reactive irreversible inhibitor for glutathione S-transferase Pi (GSTP1)
- (2016) L. A. Crawford et al. Molecular BioSystems
- Proteome-wide covalent ligand discovery in native biological systems
- (2016) Keriann M. Backus et al. NATURE
- Inhibition of Mcl-1 through covalent modification of a noncatalytic lysine side chain
- (2016) Gizem Akçay et al. Nature Chemical Biology
- Direct Monitoring of Nucleotide Turnover in Human Cell Extracts and Cells by Fluorogenic ATP Analogs
- (2015) Stephan M. Hacker et al. ACS Chemical Biology
- Identifying Drug-Target Selectivity of Small-Molecule CRM1/XPO1 Inhibitors by CRISPR/Cas9 Genome Editing
- (2015) Jasper E. Neggers et al. CHEMISTRY & BIOLOGY
- Investigating the Proteome Reactivity and Selectivity of Aryl Halides
- (2014) D. Alexander Shannon et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- The growing landscape of lysine acetylation links metabolism and cell signalling
- (2014) Chunaram Choudhary et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Lysine-targeting specificity in ubiquitin and ubiquitin-like modification pathways
- (2014) Francesca Mattiroli et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- The hereditary spastic paraplegia-related enzyme DDHD2 is a principal brain triglyceride lipase
- (2014) J. M. Inloes et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Crystal structure of wild-type and mutant human Ap4A hydrolase
- (2013) Honghua Ge et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Structure and allosteric regulation of eukaryotic 6-phosphofructokinases
- (2013) Torsten Schöneberg et al. BIOLOGICAL CHEMISTRY
- Aromatic Sulfonyl Fluorides Covalently Kinetically Stabilize Transthyretin to Prevent Amyloidogenesis while Affording a Fluorescent Conjugate
- (2013) Neil P. Grimster et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Quantitative comparison of the fasted and re-fed mouse liver phosphoproteomes using lower pH reductive dimethylation
- (2013) Joshua T. Wilson-Grady et al. METHODS
- K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions
- (2013) Jonathan M. Ostrem et al. NATURE
- A chemoproteomic platform to quantitatively map targets of lipid-derived electrophiles
- (2013) Chu Wang et al. NATURE METHODS
- Expanding the Number of ‘Druggable’ Targets: Non-Enzymes and Protein-Protein Interactions
- (2012) Leah N. Makley et al. Chemical Biology & Drug Design
- The pharmacological landscape and therapeutic potential of serine hydrolases
- (2012) Daniel A. Bachovchin et al. NATURE REVIEWS DRUG DISCOVERY
- Histone methylation: a dynamic mark in health, disease and inheritance
- (2012) Eric L. Greer et al. NATURE REVIEWS GENETICS
- Phosphofructokinase 1 Glycosylation Regulates Cell Growth and Metabolism
- (2012) W. Yi et al. SCIENCE
- Selective Depletion of Mutant p53 by Cancer Chemopreventive Isothiocyanates and Their Structure−Activity Relationships
- (2011) Xiantao Wang et al. JOURNAL OF MEDICINAL CHEMISTRY
- The opposing transcriptional functions of Sin3a and c-Myc are required to maintain tissue homeostasis
- (2011) Elisabete M. Nascimento et al. NATURE CELL BIOLOGY
- The resurgence of covalent drugs
- (2011) Juswinder Singh et al. NATURE REVIEWS DRUG DISCOVERY
- A Stilbene That Binds Selectively to Transthyretin in Cells and Remains Dark until It Undergoes a Chemoselective Reaction To Create a Bright Blue Fluorescent Conjugate
- (2010) Sungwook Choi et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Quantitative reactivity profiling predicts functional cysteines in proteomes
- (2010) Eranthie Weerapana et al. NATURE
- Chemoselective small molecules that covalently modify one lysine in a non-enzyme protein in plasma
- (2010) Sungwook Choi et al. Nature Chemical Biology
- Sin3: Master scaffold and transcriptional corepressor
- (2009) Adrienne Grzenda et al. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
- BIBW2992, an irreversible EGFR/HER2 inhibitor highly effective in preclinical lung cancer models
- (2008) D Li et al. ONCOGENE
- Conserved Themes in Target Recognition by the PAH1 and PAH2 Domains of the Sin3 Transcriptional Corepressor
- (2007) Sarata C. Sahu et al. JOURNAL OF MOLECULAR BIOLOGY
- A Tetrafluorophenyl Activated Ester Self-Assembled Monolayer for the Immobilization of Amine-Modified Oligonucleotides
- (2007) Matthew R. Lockett et al. LANGMUIR
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