Cerebrospinal Fluid Biomarkers in Highly Exposed PM2.5 Urbanites: The Risk of Alzheimer’s and Parkinson’s Diseases in Young Mexico City Residents

Cerebrospinal Fluid Biomarkers for Alzheimer's Disease

(2017) Kaj Blennow et al.   JOURNAL OF ALZHEIMERS DISEASE

The utility of α-synuclein as biofluid marker in neurodegenerative diseases: a systematic review of the literature

(2016) Anja Hviid Simonsen et al.   Biomarkers in Medicine

Alpha-Synuclein as a Biomarker for Parkinson's Disease

(2016) Anzari Atik et al.   BRAIN PATHOLOGY

Prefrontal white matter pathology in air pollution exposed Mexico City young urbanites and their potential impact on neurovascular unit dysfunction and the development of Alzheimer's disease

(2016) Lilian Calderón-Garcidueñas et al.   ENVIRONMENTAL RESEARCH

The rise and fall of insulin signaling in Alzheimer’s disease

(2016) B. Chami et al.   METABOLIC BRAIN DISEASE

Effect of dietary fat and the circadian clock on the expression of brain-derived neurotrophic factor (BDNF)

(2016) Yoni Genzer et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Oligomeric and phosphorylated alpha-synuclein as potential CSF biomarkers for Parkinson’s disease

(2016) Nour K. Majbour et al.   Molecular Neurodegeneration

Longitudinal Measurements of Cerebrospinal Fluid Biomarkers in Parkinson's Disease

(2016) Sara Hall et al.   MOVEMENT DISORDERS

Soluble prion protein and its N-terminal fragment prevent impairment of synaptic plasticity by Aβ oligomers: Implications for novel therapeutic strategy in Alzheimer's disease

(2016) Jonah J. Scott-McKean et al.   NEUROBIOLOGY OF DISEASE

Copper and Zinc Interactions with Cellular Prion Proteins Change Solubility of Full-Length Glycosylated Isoforms and Induce the Occurrence of Heterogeneous Phenotypes

(2016) Svetlana Brim et al.   PLoS One

The use of biomarkers for the etiologic diagnosis of MCI in Europe: An EADC survey

(2015) Martina Bocchetta et al.   Alzheimers & Dementia

Temporal evolution of biomarkers and cognitive markers in the asymptomatic, MCI, and dementia stage of Alzheimer's disease

(2015) Daniela Bertens et al.   Alzheimers & Dementia

Populations potentially exposed to traffic-related air pollution in seven world cities

(2015) Jason G. Su et al.   ENVIRONMENT INTERNATIONAL

Mexico City normal weight children exposed to high concentrations of ambient PM2.5 show high blood leptin and endothelin-1, vitamin D deficiency, and food reward hormone dysregulation versus low pollution controls. Relevance for obesity and Alzheimer disease

(2015) Lilian Calderón-Garcidueñas et al.   ENVIRONMENTAL RESEARCH

Particulate Matter Exposure, Prenatal and Postnatal Windows of Susceptibility, and Autism Spectrum Disorders

(2015) Amy E. Kalkbrenner et al.   EPIDEMIOLOGY

Cerebrovascular and mitochondrial abnormalities in Alzheimer’s disease: a brief overview

(2015) Cristina Carvalho et al.   JOURNAL OF NEURAL TRANSMISSION

Leptin and the brain: Influences on brain development, cognitive functioning and psychiatric disorders

(2015) Olivia M. Farr et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Absence of CCL2 and CCL3 Ameliorates Central Nervous System Grey Matter But Not White Matter Demyelination in the Presence of an Intact Blood–Brain Barrier

(2015) Katharina Janssen et al.   MOLECULAR NEUROBIOLOGY

Lower Cerebrospinal Fluid Concentration of Brain-Derived Neurotrophic Factor Predicts Progression from Mild Cognitive Impairment to Alzheimer’s Disease

(2015) Orestes Vicente Forlenza et al.   NEUROMOLECULAR MEDICINE

Manganese-Induced Parkinsonism Is Not Idiopathic Parkinson’s Disease: Environmental and Genetic Evidence

(2015) Tomás R. Guilarte et al.   TOXICOLOGICAL SCIENCES

Glutamate receptors function as scaffolds for the regulation of β-amyloid and cellular prion protein signaling complexes

(2015) Alison Hamilton et al.   Molecular Brain

Brain Imaging and Blood Biomarker Abnormalities in Children With Autosomal Dominant Alzheimer Disease

(2015) Yakeel T. Quiroz et al.   JAMA Neurology

Predicting Reduction of Cerebrospinal Fluid β-Amyloid 42 in Cognitively Healthy Controls

(2015) Niklas Mattsson et al.   JAMA Neurology

Cerebrospinal Fluid Patterns and the Risk of Future Dementia in Early, Incident Parkinson Disease

(2015) David C. Bäckström et al.   JAMA Neurology

The Impact of Air Pollutants on the Brain

(2015) Lilian Calderón-Garcidueñas et al.   JAMA Psychiatry

Alterations in brain leptin signalling in spite of unchanged CSF leptin levels in Alzheimer's disease

(2014) Silvia Maioli et al.   AGING CELL

The complexities of the pathology–pathogenesis relationship in Alzheimer disease

(2014) Rudy J. Castellani et al.   BIOCHEMICAL PHARMACOLOGY

Elevated risk of type 2 diabetes for development of Alzheimer disease: A key role for oxidative stress in brain

(2014) D. Allan Butterfield et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Independent information from cerebrospinal fluid amyloid-β and florbetapir imaging in Alzheimer's disease

(2014) Niklas Mattsson et al.   BRAIN

Detection of disease-associated α-synuclein in the cerebrospinal fluid: a feasibility study

(2014) Ursula Unterberger et al.   CLINICAL NEUROPATHOLOGY

Dysregulation of Neurotrophic and Haematopoietic Growth Factors in Alzheimer’s Disease: From Pathophysiology to Novel Treatment Strategies

(2014) Kateryna Sopova et al.   Current Alzheimer Research

Prenatal exposure to polycyclic aromatic hydrocarbons and cognitive dysfunction in children

(2014) Wiesław A. Jedrychowski et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Obesity and dementia: Adipokines interact with the brain

(2014) Ilse A.C. Arnoldussen et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Type 3 diabetes is sporadic Alzheimer׳s disease: Mini-review

(2014) Suzanne M. de la Monte   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Taste function in early stage treated and untreated Parkinson’s disease

(2014) Richard L. Doty et al.   JOURNAL OF NEUROLOGY

Correlates of cerebrospinal fluid levels of oligomeric- and total-α-synuclein in premotor, motor and dementia stages of Parkinson’s disease

(2014) Yaroslau Compta et al.   JOURNAL OF NEUROLOGY

Reduced Cerebrospinal Fluid Levels of Brain-Derived Neurotrophic Factor Is Associated With Cognitive Impairment in Late-Life Major Depression

(2014) B. S. Diniz et al.   JOURNALS OF GERONTOLOGY SERIES B-PSYCHOLOGICAL SCIENCES AND SOCIAL SCIENCES

Intracellular processing of disease-associated α-synuclein in the human brain suggests prion-like cell-to-cell spread

(2014) Gabor G. Kovacs et al.   NEUROBIOLOGY OF DISEASE

Physical Activity, Air Pollution and the Brain

(2014) Inge Bos et al.   SPORTS MEDICINE

Neuroprotective effects of physical activity on the brain: a closer look at trophic factor signaling

(2014) Cristy Phillips et al.   Frontiers in Cellular Neuroscience

Neuronal failure in Alzheimer’s disease: a view through the oxidative stress looking-glass

(2014) David J. Bonda et al.   Neuroscience Bulletin

Neuro-Endocrine Networks Controlling Immune System in Health and Disease

(2014) Claudio Procaccini et al.   Frontiers in Immunology

Alzheimer’s Amyloid-β Oligomers Rescue Cellular Prion Protein Induced Tau Reduction via the Fyn Pathway

(2013) Rong-Jie Chen et al.   ACS Chemical Neuroscience

BDNF-stimulated intracellular signalling mechanisms underlie exercise-induced improvement in spatial memory in the male Wistar rat

(2013) Ranya G. Bechara et al.   BEHAVIOURAL BRAIN RESEARCH

Oxidative stress and mitochondrial dysfunction in Alzheimer's disease

(2013) Xinglong Wang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Monocyte chemoattractant protein-1 and the blood–brain barrier

(2013) Yao Yao et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Chronic inflammation exacerbates glucose metabolism disorders in C57BL/6J mice fed with high-fat diet

(2013) Yu Wu et al.   JOURNAL OF ENDOCRINOLOGY

The role of MAC1 in diesel exhaust particle-induced microglial activation and loss of dopaminergic neuron function

(2013) Shannon Levesque et al.   JOURNAL OF NEUROCHEMISTRY

Dysregulation of leptin signaling in Alzheimer disease: evidence for neuronal leptin resistance

(2013) David J. Bonda et al.   JOURNAL OF NEUROCHEMISTRY

Cellular Form of Prion Protein Inhibits Reelin-Mediated Shedding of Caspr from the Neuronal Cell Surface to Potentiate Caspr-Mediated Inhibition of Neurite Outgrowth

(2013) V. Devanathan et al.   JOURNAL OF NEUROSCIENCE

Mexican American Children Have Differential Elevation of Metabolic Biomarkers Proportional to Obesity Status

(2013) Brian K. McFarlin et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

Serum BDNF concentrations as peripheral manifestations of depression: evidence from a systematic review and meta-analyses on 179 associations (N=9484)

(2013) M L Molendijk et al.   MOLECULAR PSYCHIATRY

Exposure to vehicle emissions results in altered blood brain barrier permeability and expression of matrix metalloproteinases and tight junction proteins in mice

(2013) Hannah A Oppenheim et al.   Particle and Fibre Toxicology

The effects of physical activity and exercise on brain-derived neurotrophic factor in healthy humans: A review

(2013) T. Huang et al.   SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS

Early Alzheimer’s and Parkinson’s Disease Pathology in Urban Children: Friend versus Foe Responses—It Is Time to Face the Evidence

(2013) Lilian Calderón-Garcidueñas et al.   Biomed Research International

Brain immune interactions and air pollution: macrophage inhibitory factor (MIF), prion cellular protein (PrPC), Interleukin-6 (IL-6), interleukin 1 receptor antagonist (IL-1Ra), and interleukin-2 (IL-2) in cerebrospinal fluid and MIF in serum differentiate urban children exposed to severe vs. low air pollution

(2013) Lilian Calderón-Garcidueñas et al.   Frontiers in Neuroscience

Ambient Air Pollution and Autism in Los Angeles County, California

(2012) Tracy Ann Becerra et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

The impact of environmental metals in young urbanites’ brains

(2012) Lilian Calderón-Garcidueñas et al.   EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY

At the crossroad of T cells, adipose tissue, and diabetes

(2012) Giuseppe Matarese et al.   IMMUNOLOGICAL REVIEWS

Acute Exercise Modulates BDNF and pro-BDNF Protein Content in Immune Cells

(2012) ANDREA BRUNELLI et al.   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

Olfactory dysfunction in Parkinson disease

(2012) Richard L. Doty   Nature Reviews Neurology

Oxidative Damage to RNA in Aging and Neurodegenerative Disorders

(2012) Akihiko Nunomura et al.   NEUROTOXICITY RESEARCH

Exposure to severe urban air pollution influences cognitive outcomes, brain volume and systemic inflammation in clinically healthy children

(2011) Lilian Calderón-Garcidueñas et al.   BRAIN AND COGNITION

Diesel Exhaust Activates and Primes Microglia: Air Pollution, Neuroinflammation, and Regulation of Dopaminergic Neurotoxicity

(2011) Shannon Levesque et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Air pollution is associated with brainstem auditory nuclei pathology and delayed brainstem auditory evoked potentials

(2011) Lilian Calderón-Garcidueñas et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

Air pollution & the brain: Subchronic diesel exhaust exposure causes neuroinflammation and elevates early markers of neurodegenerative disease

(2011) Shannon Levesque et al.   Journal of Neuroinflammation

α-Synuclein and tau concentrations in cerebrospinal fluid of patients presenting with parkinsonism: a cohort study

(2011) Brit Mollenhauer et al.   LANCET NEUROLOGY

Identifying Earlier Alzheimer’s Disease: Insights from the Preclinical and Prodromal Phases

(2011) Jose Luis Molinuevo et al.   Neurodegenerative Diseases

Neurodevelopmental expression and localization of the cellular prion protein in the central nervous system of the mouse

(2010) Stefano Benvegnù et al.   JOURNAL OF COMPARATIVE NEUROLOGY

The role of monocyte chemoattractant protein MCP1/CCL2 in neuroinflammatory diseases

(2010) Grégory Conductier et al.   JOURNAL OF NEUROIMMUNOLOGY

Role of prions in neuroprotection and neurodegeneration

(2010) Gerald W. Zamponi et al.   Prion

Brain-derived neurotrophic factor as a biomarker for mood disorders: An historical overview and future directions

(2010) Kenji Hashimoto   PSYCHIATRY AND CLINICAL NEUROSCIENCES

Temporal variation of nitro-polycyclic aromatic hydrocarbons in PM10 and PM2.5 collected in Northern Mexico City

(2010) B.L. Valle-Hernández et al.   SCIENCE OF THE TOTAL ENVIRONMENT

CSF Biomarkers

(2009) Niklas Mattsson et al.   Annals of the New York Academy of Sciences

Urban air pollution: Influences on olfactory function and pathology in exposed children and young adults

(2009) Lilian Calderón-Garcidueñas et al.   EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY

Cellular prion protein mediates impairment of synaptic plasticity by amyloid-β oligomers

(2009) Juha Laurén et al.   NATURE

Cerebrospinal Fluid Concentration of Brain-Derived Neurotrophic Factor and Cognitive Function in Non-Demented Subjects

(2009) Ge Li et al.   PLoS One

Air pollution, cognitive deficits and brain abnormalities: A pilot study with children and dogs

(2008) Lilian Calderón-Garcidueñas et al.   BRAIN AND COGNITION

Long-term Air Pollution Exposure Is Associated with Neuroinflammation, an Altered Innate Immune Response, Disruption of the Blood-Brain Barrier, Ultrafine Particulate Deposition, and Accumulation of Amyloid β-42 and α-Synuclein in Children and Young Adults

(2008) Lilian Calderón-Garcidueñas et al.   TOXICOLOGIC PATHOLOGY