The emerging roles of ATG1/ATG13 kinase complex in plants

Genome-wide identification, characterization, and expression analysis of tea plant autophagy-related genes (CsARGs) demonstrates that they play diverse roles during development and under abiotic stress

(2021) Huan Wang et al.   BMC GENOMICS

Genome-wide analysis of autophagy-related genes in Medicago truncatula highlights their roles in seed development and response to drought stress

(2021) Mingkang Yang et al.   Scientific Reports

Genomic Characterization and Expressional Profiles of Autophagy-Related Genes (ATGs) in Oilseed Crop Castor Bean (Ricinus communis L.)

(2020) Bing Han et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Comprehensive Analysis of Autophagy-Related Genes in Sweet Orange (Citrus sinensis) Highlights Their Roles in Response to Abiotic Stresses

(2020) Xing-Zheng Fu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Autophagy in plants: Physiological roles and post‐translational regulation

(2020) Hua Qi et al.   Journal of Integrative Plant Biology

Protein Phosphorylation Dynamics Under Carbon/Nitrogen-Nutrient Stress and Identification of a Cell Death-Related Receptor-Like Kinase in Arabidopsis

(2020) Xingwen Li et al.   Frontiers in Plant Science

Transcriptional Plasticity of Autophagy-Related Genes Correlates with the Genetic Response to Nitrate Starvation in Arabidopsis Thaliana

(2020) Magali Bedu et al.   Cells

ATG4 Mediated Psm ES4326/AvrRpt2-Induced Autophagy Dependent on Salicylic Acid in Arabidopsis Thaliana

(2020) Wenjun Gong et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Multiple Functions of ATG8 Family Proteins in Plant Autophagy

(2020) Fan Bu et al.   Frontiers in Cell and Developmental Biology

Phytopathogen Effectors Use Multiple Mechanisms to Manipulate Plant Autophagy

(2020) Neeraj K. Lal et al.   Cell Host & Microbe

Atg1 kinase in fission yeast is activated by Atg11-mediated dimerization and cis-autophosphorylation

(2020) Zhao-Qian Pan et al.   eLife

In Silico Analyses of Autophagy-Related Genes in Rapeseed (Brassica napus L.) under Different Abiotic Stresses and in Various Tissues

(2020) Elham Mehri Eshkiki et al.   Plants-Basel

Identification of transcription factors that regulate ATG8 expression and autophagy in Arabidopsis

(2019) Ping Wang et al.   Autophagy

ATG8-Binding UIM Proteins Define a New Class of Autophagy Adaptors and Receptors

(2019) Richard S. Marshall et al.   CELL

Multiple Regulatory Levels Shape Autophagy Activity in Plants

(2019) Mingkang Yang et al.   Frontiers in Plant Science

Autophagy in Plant: A New Orchestrator in the Regulation of the Phytohormones Homeostasis

(2019) Wentao Gou et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Marchantia polymorpha, a New Model Plant for Autophagy Studies

(2019) Takuya Norizuki et al.   Frontiers in Plant Science

Combating stress: the interplay between hormone signaling and autophagy in plants

(2019) Ching-Yi Liao et al.   JOURNAL OF EXPERIMENTAL BOTANY

Arabidopsis SINAT Proteins Control Autophagy by Mediating Ubiquitylation and Degradation of ATG13

(2019) Hua Qi et al.   PLANT CELL

Genetic Analyses of the Arabidopsis ATG1 Kinase Complex Reveal Both Kinase-Dependent and Independent Autophagic Routes during Fixed-Carbon Starvation

(2019) Xiao Huang et al.   PLANT CELL

Contrasting and emerging roles of autophagy in plant immunity

(2019) Alexandre Y Leary et al.   CURRENT OPINION IN PLANT BIOLOGY

Autophagy: The Master of Bulk and Selective Recycling

(2018) Richard S. Marshall et al.   Annual Review of Plant Biology

Involvement of TOR signaling motif in the regulation of plant autophagy

(2018) Ora Son et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Transcriptional and post-transcriptional regulation of autophagy in the yeastSaccharomyces cerevisiae

(2018) Elizabeth Delorme-Axford et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genome-wide sequence and expressional analysis of autophagy Gene family in bread wheat ( Triticum aestivum L.)

(2018) Wenjie Yue et al.   JOURNAL OF PLANT PHYSIOLOGY

Genome-wide analysis of autophagy-related genes (ARGs) in grapevine and plant tolerance to copper stress

(2018) Lingfei Shangguan et al.   PLANTA

New advances in autophagy in plants: Regulation, selectivity and function

(2018) Ping Wang et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

A regulatory role of autophagy for resetting the memory of heat stress in plants

(2018) Mastoureh Sedaghatmehr et al.   PLANT CELL AND ENVIRONMENT

BZR1 mediates brassinosteroid-induced autophagy and nitrogen starvation tolerance in tomato

(2018) Yu Wang et al.   PLANT PHYSIOLOGY

TRAF Family Proteins Regulate Autophagy Dynamics by Modulating AUTOPHAGY PROTEIN6 Stability in Arabidopsis

(2017) Hua Qi et al.   PLANT CELL

Genome-wide analysis of autophagy-related genes in banana highlights MaATG8s in cell death and autophagy in immune response to Fusarium wilt

(2017) Yunxie Wei et al.   PLANT CELL REPORTS

TOR-Dependent and -Independent Pathways Regulate Autophagy in Arabidopsis thaliana

(2017) Yunting Pu et al.   Frontiers in Plant Science

The AMP-Activated Protein Kinase KIN10 Is Involved in the Regulation of Autophagy in Arabidopsis

(2017) Liang Chen et al.   Frontiers in Plant Science

The ULK1 complex mediates MTORC1 signaling to the autophagy initiation machinery via binding and phosphorylating ATG14

(2016) Ji-Man Park et al.   Autophagy

Genome-wide analysis of autophagy-associated genes in foxtail millet (Setaria italica L.) and characterization of the function of SiATG8a in conferring tolerance to nitrogen starvation in rice

(2016) Weiwei Li et al.   BMC GENOMICS

The Intrinsically Disordered Protein Atg13 Mediates Supramolecular Assembly of Autophagy Initiation Complexes

(2016) Hayashi Yamamoto et al.   DEVELOPMENTAL CELL

Nutrient-regulated Phosphorylation of ATG13 Inhibits Starvation-induced Autophagy

(2016) Cindy Puente et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fine-tuning of ULK1 mRNA and protein levels is required for autophagy oscillation

(2016) Francesca Nazio et al.   JOURNAL OF CELL BIOLOGY

Transcriptional regulation of mammalian autophagy at a glance

(2016) Jens Füllgrabe et al.   JOURNAL OF CELL SCIENCE

Identification of Barley (Hordeum vulgare L.) Autophagy Genes and Their Expression Levels during Leaf Senescence, Chronic Nitrogen Limitation and in Response to Dark Exposure

(2016) Liliana Avila-Ospina et al.   Agronomy-Basel

Orchestrated Action of PP2A Antagonizes Atg13 Phosphorylation and Promotes Autophagy after the Inactivation of TORC1

(2016) Akter MST Yeasmin et al.   PLoS One

BECN1s, a short splice variant of BECN1, functions in mitophagy

(2015) Bing Cheng et al.   Autophagy

Expression of a ULK1/2 binding-deficient ATG13 variant can partially restore autophagic activity in ATG13-deficient cells

(2015) Nora Hieke et al.   Autophagy

Tomato HsfA1a plays a critical role in plant drought tolerance by activatingATGgenes and inducing autophagy

(2015) Yu Wang et al.   Autophagy

Atg1 family kinases in autophagy initiation

(2015) Nobuo N. Noda et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

A comprehensive, genome-wide analysis of autophagy-related genes identified in tobacco suggests a central role of autophagy in plant response to various environmental cues

(2015) Xue-mei Zhou et al.   DNA RESEARCH

Receptor-Bound Targets of Selective Autophagy Use a Scaffold Protein to Activate the Atg1 Kinase

(2015) Roarke A. Kamber et al.   MOLECULAR CELL

Small Molecule Inhibition of the Autophagy Kinase ULK1 and Identification of ULK1 Substrates

(2015) Daniel F. Egan et al.   MOLECULAR CELL

Autophagic Recycling Plays a Central Role in Maize Nitrogen Remobilization

(2015) Faqiang Li et al.   PLANT CELL

Structure of the Human Atg13-Atg101 HORMA Heterodimer: an Interaction Hub within the ULK1 Complex

(2015) Shiqian Qi et al.   STRUCTURE

Regulation of autophagy by coordinated action of mTORC1 and protein phosphatase 2A

(2015) Pui-Mun Wong et al.   Nature Communications

Comparative transcriptome analysis of grapevine in response to copper stress

(2015) Xiangpeng Leng et al.   Scientific Reports

Alternative Messenger RNA Splicing of Autophagic Gene Beclin 1 in Human B-cell Acute Lymphoblastic Leukemia Cells

(2014) Yu-Na Niu et al.   Asian Pacific Journal of Cancer Prevention

Atg17/FIP200 localizes to perilysosomal Ref(2)P aggregates and promotes autophagy by activation of Atg1 inDrosophila

(2014) Péter Nagy et al.   Autophagy

Posttranslational modification of autophagy-related proteins in macroautophagy

(2014) Yangchun Xie et al.   Autophagy

The HORMA domain: an evolutionarily conserved domain discovered in chromatin-associated proteins, has unanticipated diverse functions

(2014) K. Muniyappa et al.   GENE

Early Steps in Autophagy Depend on Direct Phosphorylation of Atg9 by the Atg1 Kinase

(2014) Daniel Papinski et al.   MOLECULAR CELL

Structural basis of starvation-induced assembly of the autophagy initiation complex

(2014) Yuko Fujioka et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

AUTOPHAGY-RELATED11 Plays a Critical Role in General Autophagy- and Senescence-Induced Mitophagy in Arabidopsis

(2014) F. Li et al.   PLANT CELL

The Putative HORMA Domain Protein Atg101 Dimerizes and Is Required for Starvation-Induced and Selective Autophagy inDrosophila

(2014) Krisztina Hegedűs et al.   Biomed Research International

The machinery of macroautophagy

(2013) Yuchen Feng et al.   CELL RESEARCH

mTOR inhibits autophagy by controlling ULK1 ubiquitylation, self-association and function through AMBRA1 and TRAF6

(2013) Francesca Nazio et al.   NATURE CELL BIOLOGY

ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase

(2013) Ryan C. Russell et al.   NATURE CELL BIOLOGY

Autophagy in Human Health and Disease

(2013) Augustine M.K. Choi et al.   NEW ENGLAND JOURNAL OF MEDICINE

A HORMA domain in Atg13 mediates PI 3-kinase recruitment in autophagy

(2013) C. C. Jao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autophagy: Pathways for Self-Eating in Plant Cells

(2012) Yimo Liu et al.   Annual Review of Plant Biology

Autophagy is differentially induced in prostate cancer LNCaP, DU145 and PC-3 cells via distinct splicing profiles of ATG5

(2012) Dong-Yun Ouyang et al.   Autophagy

Binding of the Atg1/ULK1 kinase to the ubiquitin-like protein Atg8 regulates autophagy

(2012) Claudine Kraft et al.   EMBO JOURNAL

Identification of Novelin vivoMAP Kinase Substrates inArabidopsis thalianaThrough Use of Tandem Metal Oxide Affinity Chromatography

(2012) Wolfgang Hoehenwarter et al.   MOLECULAR & CELLULAR PROTEOMICS

Analysis of Autophagy Genes in Microalgae: Chlorella as a Potential Model to Study Mechanism of Autophagy

(2012) Qiao Jiang et al.   PLoS One

Atg16L2, a novel isoform of mammalian Atg16L that is not essential for canonical autophagy despite forming an Atg12–5-16L2 complex

(2011) Koutaro Ishibashi et al.   Autophagy

Atg13 and FIP200 act independently of Ulk1 and Ulk2 in autophagy induction

(2011) Sebastian Alers et al.   Autophagy

Role of autophagy in disease resistance and hypersensitive response-associated cell death

(2011) D Hofius et al.   CELL DEATH AND DIFFERENTIATION

Genome-Wide Identification, Classification, and Expression Analysis of Autophagy-Associated Gene Homologues in Rice (Oryza sativa L.)

(2011) K. Xia et al.   DNA RESEARCH

Hsp90-Cdc37 Chaperone Complex Regulates Ulk1- and Atg13-Mediated Mitophagy

(2011) Joung Hyuck Joo et al.   MOLECULAR CELL

The ATG1/ATG13 Protein Kinase Complex Is Both a Regulator and a Target of Autophagic Recycling in Arabidopsis

(2011) A. Suttangkakul et al.   PLANT CELL

ATG2, an autophagy-related protein, negatively affects powdery mildew resistance and mildew-induced cell death in Arabidopsis

(2011) Yiping Wang et al.   PLANT JOURNAL

The role of the Atg1/ULK1 complex in autophagy regulation

(2010) Noboru Mizushima   CURRENT OPINION IN CELL BIOLOGY

Current knowledge of the pre-autophagosomal structure (PAS)

(2010) Kuninori Suzuki et al.   FEBS LETTERS

The dynamic interaction of AMBRA1 with the dynein motor complex regulates mammalian autophagy

(2010) Sabrina Di Bartolomeo et al.   JOURNAL OF CELL BIOLOGY

A novel, human Atg13 binding protein, Atg101, interacts with ULK1 and is essential for macroautophagy

(2009) Carol A. Mercer et al.   Autophagy

epg-1functions in autophagy-regulated processes and may encode a highly divergent Atg13 homolog inC. elegans

(2009) E Tian et al.   Autophagy

Atg101, a novel mammalian autophagy protein interacting with Atg13

(2009) Nao Hosokawa et al.   Autophagy

Characterization of the Atg17–Atg29–Atg31 complex specifically required for starvation-induced autophagy in Saccharomyces cerevisiae

(2009) Yukiko Kabeya et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

ULK1·ATG13·FIP200 Complex Mediates mTOR Signaling and Is Essential for Autophagy

(2009) Ian G. Ganley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An Atg1/Atg13 Complex with Multiple Roles in TOR-mediated Autophagy Regulation

(2009) Yu-Yun Chang et al.   MOLECULAR BIOLOGY OF THE CELL

ULK-Atg13-FIP200 Complexes Mediate mTOR Signaling to the Autophagy Machinery

(2009) Chang Hwa Jung et al.   MOLECULAR BIOLOGY OF THE CELL

The Tor and PKA signaling pathways independently target the Atg1/Atg13 protein kinase complex to control autophagy

(2009) J. S. Stephan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells

(2008) Taichi Hara et al.   JOURNAL OF CELL BIOLOGY

Kinase-Inactivated ULK Proteins Inhibit Autophagy via Their Conserved C-Terminal Domains Using an Atg13-Independent Mechanism

(2008) E. Y. W. Chan et al.   MOLECULAR AND CELLULAR BIOLOGY

FIP200, a key signaling node to coordinately regulate various cellular processes

(2007) Boyi Gan et al.   CELLULAR SIGNALLING