Cdc14 spatiotemporally dephosphorylates Atg13 to activate autophagy during meiotic divisions

Phosphoregulation of the autophagy machinery by kinases and phosphatases

(2021) Mariya Licheva et al.   Autophagy

Programmed cortical ER collapse drives selective ER degradation and inheritance in yeast meiosis

(2021) George Maxwell Otto et al.   JOURNAL OF CELL BIOLOGY

Autophagy of an Amyloid-like Translational Repressor Regulates Meiotic Exit

(2020) Fei Wang et al.   DEVELOPMENTAL CELL

Autophagy prevents runaway meiotic divisions

(2020) Fei Wang et al.   Autophagy

Autophagy Regulation by the Translation Machinery and Its Implications in Cancer

(2020) Pilar Sarah Acevo-Rodríguez et al.   Frontiers in Oncology

ULK1-ATG13 and their mitotic phospho-regulation by CDK1 connect autophagy to cell cycle

(2020) Zhiyuan Li et al.   PLOS BIOLOGY

Mitotic phosphorylation of the ULK complex regulates cell cycle progression

(2020) Akinori Yamasaki et al.   PLOS BIOLOGY

CDK1, the Other ‘Master Regulator’ of Autophagy

(2020) Richard I. Odle et al.   TRENDS IN CELL BIOLOGY

PP2C phosphatases promote autophagy by dephosphorylation of the Atg1 complex

(2019) Gonen Memisoglu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A fully-automated, robust, and versatile algorithm for long-term budding yeast segmentation and tracking

(2019) N. Ezgi Wood et al.   PLoS One

Transcriptional Regulation of Autophagy: Mechanisms and Diseases

(2019) Chiara Di Malta et al.   Frontiers in Cell and Developmental Biology

Multilayered Control of Protein Turnover by TORC1 and Atg1

(2019) Zehan Hu et al.   Cell Reports

An mTORC1-to-CDK1 Switch Maintains Autophagy Suppression during Mitosis

(2019) Richard I. Odle et al.   MOLECULAR CELL

Phosphorylation-Mediated Clearance of Amyloid-like Assemblies in Meiosis

(2018) Kayla Carpenter et al.   DEVELOPMENTAL CELL

Cdc14 Phosphatase Promotes TORC1-Regulated Autophagy in Yeast

(2018) Akihiro Kondo et al.   JOURNAL OF MOLECULAR BIOLOGY

Cargo recognition and degradation by selective autophagy

(2018) Damián Gatica et al.   NATURE CELL BIOLOGY

SWISS-MODEL: homology modelling of protein structures and complexes

(2018) Andrew Waterhouse et al.   NUCLEIC ACIDS RESEARCH

Integration of Multiple Metabolic Signals Determines Cell Fate Prior to Commitment

(2018) Orlando Argüello-Miranda et al.   MOLECULAR CELL

A PxL motif promotes timely cell cycle substrate dephosphorylation by the Cdc14 phosphatase

(2018) Meghna Kataria et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A reversible phospho-switch mediated by ULK1 regulates the activity of autophagy protease ATG4B

(2017) N. Pengo et al.   Nature Communications

Distinct temporal requirements for autophagy and the proteasome in yeast meiosis

(2016) Fu-Ping Wen et al.   Autophagy

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

(2016) Daniel J Klionsky et al.   Autophagy

The Intrinsically Disordered Protein Atg13 Mediates Supramolecular Assembly of Autophagy Initiation Complexes

(2016) Hayashi Yamamoto et al.   DEVELOPMENTAL CELL

The Atg1–kinase complex tethers Atg9-vesicles to initiate autophagy

(2016) Yijian Rao et al.   Nature Communications

Sec24 phosphorylation regulates autophagosome abundance during nutrient deprivation

(2016) Saralin Davis et al.   eLife

Elimination of paternal mitochondria in mouse embryos occurs through autophagic degradation dependent on PARKIN and MUL1

(2016) Rebecca Rojansky et al.   eLife

Orchestrated Action of PP2A Antagonizes Atg13 Phosphorylation and Promotes Autophagy after the Inactivation of TORC1

(2016) Akter MST Yeasmin et al.   PLoS One

Regulated Formation of an Amyloid-like Translational Repressor Governs Gametogenesis

(2015) Luke E. Berchowitz et al.   CELL

mTOR: a pharmacologic target for autophagy regulation

(2015) Young Chul Kim et al.   JOURNAL OF CLINICAL INVESTIGATION

Receptor-Bound Targets of Selective Autophagy Use a Scaffold Protein to Activate the Atg1 Kinase

(2015) Roarke A. Kamber et al.   MOLECULAR CELL

Molecular Mechanisms that Restrict Yeast Centrosome Duplication to One Event per Cell Cycle

(2014) Menattallah Elserafy et al.   CURRENT BIOLOGY

Paternal Mitochondrial Destruction after Fertilization Is Mediated by a Common Endocytic and Autophagic Pathway in Drosophila

(2014) Yoav Politi et al.   DEVELOPMENTAL CELL

Hrr25 kinase promotes selective autophagy by phosphorylating the cargo receptor Atg19

(2014) T. Pfaffenwimmer et al.   EMBO REPORTS

The Cdk/Cdc14 Module Controls Activation of the Yen1 Holliday Junction Resolvase to Promote Genome Stability

(2014) Christie L. Eissler et al.   MOLECULAR CELL

Early Steps in Autophagy Depend on Direct Phosphorylation of Atg9 by the Atg1 Kinase

(2014) Daniel Papinski et al.   MOLECULAR CELL

Cargo recognition and trafficking in selective autophagy

(2014) Alexandra Stolz et al.   NATURE CELL BIOLOGY

Assembly and dynamics of the autophagy-initiating Atg1 complex

(2014) G. Stjepanovic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Licensing of Yeast Centrosome Duplication Requires Phosphoregulation of Sfi1

(2014) Jennifer S. Avena et al.   PLoS Genetics

The Rim15-Endosulfine-PP2ACdc55 Signalling Module Regulates Entry into Gametogenesis and Quiescence via Distinct Mechanisms in Budding Yeast

(2014) Sourav Sarkar et al.   PLoS Genetics

Autophagy-Mediated Tumor Promotion

(2013) Jessie Yanxiang Guo et al.   CELL

Comprehensive Proteomics Analysis Reveals New Substrates and Regulators of the Fission Yeast Clp1/Cdc14 Phosphatase

(2013) Jun-Song Chen et al.   MOLECULAR & CELLULAR PROTEOMICS

An Algorithm to Automate Yeast Segmentation and Tracking

(2013) Andreas Doncic et al.   PLoS One

Atg29 phosphorylation regulates coordination of the Atg17-Atg31-Atg29 complex with the Atg11 scaffold during autophagy initiation

(2013) K. Mao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synthetic gene expression perturbation systems with rapid, tunable, single-gene specificity in yeast

(2012) R. Scott McIsaac et al.   NUCLEIC ACIDS RESEARCH

Autophagy: Renovation of Cells and Tissues

(2011) Noboru Mizushima et al.   CELL

Sporulation in the Budding YeastSaccharomyces cerevisiae

(2011) Aaron M. Neiman   GENETICS

An Atg13 Protein-mediated Self-association of the Atg1 Protein Kinase Is Important for the Induction of Autophagy

(2011) Yuh-Ying Yeh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cdc14 Phosphatases Preferentially Dephosphorylate a Subset of Cyclin-dependent kinase (Cdk) Sites Containing Phosphoserine

(2011) Steven C. Bremmer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphorylation of Serine 114 on Atg32 mediates mitophagy

(2011) Yoshimasa Aoki et al.   MOLECULAR BIOLOGY OF THE CELL

Regulation of entry into gametogenesis

(2011) F. J. van Werven et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

High-Resolution View of the Yeast Meiotic Program Revealed by Ribosome Profiling

(2011) G. A. Brar et al.   SCIENCE

Degradation of Paternal Mitochondria by Fertilization-Triggered Autophagy in C. elegans Embryos

(2011) M. Sato et al.   SCIENCE

The role of the Atg1/ULK1 complex in autophagy regulation

(2010) Noboru Mizushima   CURRENT OPINION IN CELL BIOLOGY

Mutants of the Saccharomyces cerevisiae VPS genes CCZ1 and YPT7 are blocked in different stages of sporulation

(2010) Iga Piekarska et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Autophosphorylation Within the Atg1 Activation Loop Is Required for Both Kinase Activity and the Induction of Autophagy in Saccharomyces cerevisiae

(2010) Y.-Y. Yeh et al.   GENETICS

Global Analysis of Cdc14 Phosphatase Reveals Diverse Roles in Mitotic Processes

(2010) Joanna Bloom et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Chaperone Cascade Sorts Proteins for Posttranslational Membrane Insertion into the Endoplasmic Reticulum

(2010) Fei Wang et al.   MOLECULAR CELL

Regulation Mechanisms and Signaling Pathways of Autophagy

(2009) Congcong He et al.   Annual Review of Genetics

Autophagy: Regulation and role in disease

(2009) Alfred J. Meijer et al.   CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES

Tor Directly Controls the Atg1 Kinase Complex To Regulate Autophagy

(2009) Y. Kamada et al.   MOLECULAR AND CELLULAR BIOLOGY

Meiosis I Is Established through Division-Specific Translational Control of a Cyclin

(2008) Thomas M. Carlile et al.   CELL

Cdc14B depletion leads to centriole amplification, and its overexpression prevents unscheduled centriole duplication

(2008) Jun Wu et al.   JOURNAL OF CELL BIOLOGY

Organization of the Pre-autophagosomal Structure Responsible for Autophagosome Formation

(2008) Tomoko Kawamata et al.   MOLECULAR BIOLOGY OF THE CELL