标题
Transcriptional Regulation of Autophagy: Mechanisms and Diseases
作者
关键词
-
出版物
Frontiers in Cell and Developmental Biology
Volume 7, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2019-07-02
DOI
10.3389/fcell.2019.00114
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Biological Functions of Autophagy Genes: A Disease Perspective
- (2019) Beth Levine et al. CELL
- Loss of Sirtuin 1 Alters the Secretome of Breast Cancer Cells by Impairing Lysosomal Integrity
- (2019) Arash Latifkar et al. DEVELOPMENTAL CELL
- Transcriptional regulation of autophagy-lysosomal function in BRAF-driven melanoma progression and chemoresistance
- (2019) Shun Li et al. Nature Communications
- The complex relationship between TFEB transcription factor phosphorylation and subcellular localization
- (2018) Rosa Puertollano et al. EMBO JOURNAL
- Protein phosphatase 2A stimulates activation of TFEB and TFE3 transcription factors in response to oxidative stress
- (2018) José A. Martina et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Aspirin induces Lysosomal biogenesis and attenuates Amyloid plaque pathology in a mouse model of Alzheimer's disease via PPARα
- (2018) Sujyoti Chandra et al. JOURNAL OF NEUROSCIENCE
- FoxO transcription factors modulate autophagy and proteoglycan 4 in cartilage homeostasis and osteoarthritis
- (2018) Tokio Matsuzaki et al. Science Translational Medicine
- A TFEB nuclear export signal integrates amino acid supply and glucose availability
- (2018) Linxin Li et al. Nature Communications
- mTOR-dependent phosphorylation controls TFEB nuclear export
- (2018) Gennaro Napolitano et al. Nature Communications
- DAF-16/FOXO and HLH-30/TFEB function as combinatorial transcription factors to promote stress resistance and longevity
- (2018) Xin-Xuan Lin et al. Nature Communications
- The transcription factors TFE3 and TFEB amplify p53 dependent transcriptional programs in response to DNA damage
- (2018) Eutteum Jeong et al. eLife
- mTORC1 hyperactivation arrests bone growth in lysosomal storage disorders by suppressing autophagy
- (2017) Rosa Bartolomeo et al. JOURNAL OF CLINICAL INVESTIGATION
- Bromodomain Protein BRD4 Is a Transcriptional Repressor of Autophagy and Lysosomal Function
- (2017) Jun-ichi Sakamaki et al. MOLECULAR CELL
- Activation of AMPK/mTORC1-Mediated Autophagy by Metformin Reverses Clk1 Deficiency-Sensitized Dopaminergic Neuronal Death
- (2017) Qiuting Yan et al. MOLECULAR PHARMACOLOGY
- Enhancement of hepatic autophagy increases ureagenesis and protects against hyperammonemia
- (2017) Leandro R. Soria et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Transcriptional activation of RagD GTPase controls mTORC1 and promotes cancer growth
- (2017) Chiara Di Malta et al. SCIENCE
- Small-molecule TFEB pathway agonists that ameliorate metabolic syndrome in mice and extend C. elegans lifespan
- (2017) Chensu Wang et al. Nature Communications
- mTORC1-independent TFEB activation via Akt inhibition promotes cellular clearance in neurodegenerative storage diseases
- (2017) Michela Palmieri et al. Nature Communications
- Transcriptional regulation of mammalian autophagy at a glance
- (2016) Jens Füllgrabe et al. JOURNAL OF CELL SCIENCE
- Activation of the transcription factor EB rescues lysosomal abnormalities in cystinotic kidney cells
- (2016) Laura R. Rega et al. KIDNEY INTERNATIONAL
- AMPK–SKP2–CARM1 signalling cascade in transcriptional regulation of autophagy
- (2016) Hi-Jai R. Shin et al. NATURE
- Protein kinase C controls lysosome biogenesis independently of mTORC1
- (2016) Yang Li et al. NATURE CELL BIOLOGY
- Codon optimality controls differential mRNA translation during amino acid starvation
- (2016) Mridusmita Saikia et al. RNA
- Lateral Thinking: How Histone Modifications Regulate Gene Expression
- (2016) Moyra Lawrence et al. TRENDS IN GENETICS
- Curcumin targets the TFEB-lysosome pathway for induction of autophagy
- (2016) Jianbin Zhang et al. Oncotarget
- Dysregulation of Nutrient Sensing and CLEARance in Presenilin Deficiency
- (2016) Kavya Reddy et al. Cell Reports
- Deacetylation of TFEB promotes fibrillar Aβ degradation by upregulating lysosomal biogenesis in microglia
- (2016) Jintao Bao et al. Protein & Cell
- Transcriptional and epigenetic regulation of autophagy in aging
- (2015) Louis R Lapierre et al. Autophagy
- The role for autophagy in cancer
- (2015) Eileen White JOURNAL OF CLINICAL INVESTIGATION
- Neuronal-Targeted TFEB Accelerates Lysosomal Degradation of APP, Reducing A Generation and Amyloid Plaque Pathogenesis
- (2015) Q. Xiao et al. JOURNAL OF NEUROSCIENCE
- FGF signalling regulates bone growth through autophagy
- (2015) Laura Cinque et al. NATURE
- Transcriptional control of autophagy–lysosome function drives pancreatic cancer metabolism
- (2015) Rushika M. Perera et al. NATURE
- Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB
- (2015) Diego L. Medina et al. NATURE CELL BIOLOGY
- Autophagy at the crossroads of catabolism and anabolism
- (2015) Jasvinder Kaur et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Compromised autophagy and neurodegenerative diseases
- (2015) Fiona M. Menzies et al. NATURE REVIEWS NEUROSCIENCE
- Genetic and Chemical Activation of TFEB Mediates Clearance of Aggregated α-Synuclein
- (2015) Kiri Kilpatrick et al. PLoS One
- MITF drives endolysosomal biogenesis and potentiates Wnt signaling in melanoma cells
- (2015) Diego Ploper et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pharmaceutical screen identifies novel target processes for activation of autophagy with a broad translational potential
- (2015) Santosh Chauhan et al. Nature Communications
- Atomistic Autophagy: The Structures of Cellular Self-Digestion
- (2014) James H. Hurley et al. CELL
- Selective clearance of aberrant tau proteins and rescue of neurotoxicity by transcription factor EB
- (2014) V. A. Polito et al. EMBO Molecular Medicine
- The cytoplasmic side of p53's oncosuppressive activities
- (2014) Anna Comel et al. FEBS LETTERS
- Enhancing Astrocytic Lysosome Biogenesis Facilitates A Clearance and Attenuates Amyloid Plaque Pathogenesis
- (2014) Q. Xiao et al. JOURNAL OF NEUROSCIENCE
- Transcriptional regulation of autophagy by an FXR–CREB axis
- (2014) Sunmi Seok et al. NATURE
- Nutrient-sensing nuclear receptors coordinate autophagy
- (2014) Jae Man Lee et al. NATURE
- Polyglutamine-expanded androgen receptor interferes with TFEB to elicit autophagy defects in SBMA
- (2014) Constanza J Cortes et al. NATURE NEUROSCIENCE
- Molecular genetics and cellular features of TFE3 and TFEB fusion kidney cancers
- (2014) Eric C. Kauffman et al. Nature Reviews Urology
- The Nutrient-Responsive Transcription Factor TFE3 Promotes Autophagy, Lysosomal Biogenesis, and Clearance of Cellular Debris
- (2014) J. A. Martina et al. Science Signaling
- FOXO transcription factors: key regulators of cellular quality control
- (2014) Ashley E. Webb et al. TRENDS IN BIOCHEMICAL SCIENCES
- The Sestrins Interact with GATOR2 to Negatively Regulate the Amino-Acid-Sensing Pathway Upstream of mTORC1
- (2014) Lynne Chantranupong et al. Cell Reports
- Gene transfer of master autophagy regulator TFEB results in clearance of toxic protein and correction of hepatic disease in alpha-1-anti-trypsin deficiency
- (2013) Nunzia Pastore et al. EMBO Molecular Medicine
- Transcription factor EB (TFEB) is a new therapeutic target for Pompe disease
- (2013) Carmine Spampanato et al. EMBO Molecular Medicine
- A RANKL-PKC -TFEB signaling cascade is necessary for lysosomal biogenesis in osteoclasts
- (2013) M. Ferron et al. GENES & DEVELOPMENT
- Global genomic profiling reveals an extensive p53-regulated autophagy program contributing to key p53 responses
- (2013) D. Kenzelmann Broz et al. GENES & DEVELOPMENT
- TFEB regulates lysosomal proteostasis
- (2013) Wensi Song et al. HUMAN MOLECULAR GENETICS
- Epigenetic Regulation of Autophagy by the Methyltransferase G9a
- (2013) A. Artal-Martinez de Narvajas et al. MOLECULAR AND CELLULAR BIOLOGY
- ZKSCAN3 Is a Master Transcriptional Repressor of Autophagy
- (2013) Santosh Chauhan et al. MOLECULAR CELL
- The histone H4 lysine 16 acetyltransferase hMOF regulates the outcome of autophagy
- (2013) Jens Füllgrabe et al. NATURE
- TFEB controls cellular lipid metabolism through a starvation-induced autoregulatory loop
- (2013) Carmine Settembre et al. NATURE CELL BIOLOGY
- TFEB-mediated autophagy rescues midbrain dopamine neurons from -synuclein toxicity
- (2013) M. Decressac et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB
- (2012) Jose A. Martina et al. Autophagy
- A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB
- (2012) Carmine Settembre et al. EMBO JOURNAL
- Restricted leucine zipper dimerization and specificity of DNA recognition of the melanocyte master regulator MITF
- (2012) V. Pogenberg et al. GENES & DEVELOPMENT
- The Autophagy-related Gene 14 (Atg14) Is Regulated by Forkhead Box O Transcription Factors and Circadian Rhythms and Plays a Critical Role in Hepatic Autophagy and Lipid Metabolism
- (2012) Xiwen Xiong et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Transcriptional integration of metabolism by the nuclear sterol-activated receptors LXR and FXR
- (2012) Anna C. Calkin et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- The histone H3 lysine 56 acetylation pathway is regulated by target of rapamycin (TOR) signaling and functions directly in ribosomal RNA biogenesis
- (2012) Hongfeng Chen et al. NUCLEIC ACIDS RESEARCH
- The Transcription Factor TFEB Links mTORC1 Signaling to Transcriptional Control of Lysosome Homeostasis
- (2012) A. Roczniak-Ferguson et al. Science Signaling
- PGC-1 Rescues Huntington's Disease Proteotoxicity by Preventing Oxidative Stress and Promoting TFEB Function
- (2012) T. Tsunemi et al. Science Translational Medicine
- Chaperone-mediated autophagy: a unique way to enter the lysosome world
- (2012) Susmita Kaushik et al. TRENDS IN CELL BIOLOGY
- The Role of Atg Proteins in Autophagosome Formation
- (2011) Noboru Mizushima et al. Annual Review of Cell and Developmental Biology
- Microautophagy in mammalian cells: Revisiting a 40-year-old conundrum
- (2011) Dalibor Mijaljica et al. Autophagy
- The autophagy initiating kinase ULK1 is regulated via opposing phosphorylation by AMPK and mTOR
- (2011) Dan Egan et al. Autophagy
- Autophagy: Renovation of Cells and Tissues
- (2011) Noboru Mizushima et al. CELL
- Transcriptional Activation of Lysosomal Exocytosis Promotes Cellular Clearance
- (2011) Diego L. Medina et al. DEVELOPMENTAL CELL
- Microautophagy of Cytosolic Proteins by Late Endosomes
- (2011) Ranjit Sahu et al. DEVELOPMENTAL CELL
- Regulation of TFEB and V-ATPases by mTORC1
- (2011) Samuel Peña-Llopis et al. EMBO JOURNAL
- JNK regulates FoxO-dependent autophagy in neurons
- (2011) P. Xu et al. GENES & DEVELOPMENT
- Characterization of the CLEAR network reveals an integrated control of cellular clearance pathways
- (2011) Michela Palmieri et al. HUMAN MOLECULAR GENETICS
- Spermidine and resveratrol induce autophagy by distinct pathways converging on the acetylproteome
- (2011) Eugenia Morselli et al. JOURNAL OF CELL BIOLOGY
- AMPK promotes skeletal muscle autophagy through activation of forkhead FoxO3a and interaction with Ulk1
- (2011) Anthony MJ Sanchez et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Biology and Clinical Relevance of the Micropthalmia Family of Transcription Factors in Human Cancer
- (2011) Rizwan Haq et al. JOURNAL OF CLINICAL ONCOLOGY
- The cellular pathology of lysosomal diseases
- (2011) Timothy M Cox et al. JOURNAL OF PATHOLOGY
- Control of autophagy as a therapy for neurodegenerative disease
- (2011) Harry Harris et al. Nature Reviews Neurology
- The pro-longevity gene FoxO3 is a direct target of the p53 tumor suppressor
- (2011) V M Renault et al. ONCOGENE
- Epigenetic Regulation of E2F-1-Dependent Bnip3 Transcription and Cell Death by Nuclear Factor-κB and Histone Deacetylase-1
- (2011) Hongying Gang et al. PEDIATRIC CARDIOLOGY
- Nutrient starvation elicits an acute autophagic response mediated by Ulk1 dephosphorylation and its subsequent dissociation from AMPK
- (2011) L. Shang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- TFEB Links Autophagy to Lysosomal Biogenesis
- (2011) C. Settembre et al. SCIENCE
- Protein deacetylation by sirtuins: delineating a post-translational regulatory program responsive to nutrient and redox stressors
- (2010) Jianjun Bao et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Pathogenic Lysosomal Depletion in Parkinson's Disease
- (2010) B. Dehay et al. JOURNAL OF NEUROSCIENCE
- Cytosolic FoxO1 is essential for the induction of autophagy and tumour suppressor activity
- (2010) Ying Zhao et al. NATURE CELL BIOLOGY
- SIRT1 Negatively Regulates the Mammalian Target of Rapamycin
- (2010) Hiyaa Singhee Ghosh et al. PLoS One
- Autophagy and Metabolism
- (2010) J. D. Rabinowitz et al. SCIENCE
- Physiological role of autophagy as an intracellular recycling system: With an emphasis on nutrient metabolism
- (2010) Akiko Kuma et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Regulation Mechanisms and Signaling Pathways of Autophagy
- (2009) Congcong He et al. Annual Review of Genetics
- P53 negatively regulates the transcriptional activity of FOXO3a under oxidative stress
- (2009) Yasuo Miyaguchi et al. CELL BIOLOGY INTERNATIONAL
- Hepatic Autophagy Is Suppressed in the Presence of Insulin Resistance and Hyperinsulinemia
- (2009) Hui-Yu Liu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- MDM2 Acts Downstream of p53 as an E3 Ligase to Promote FOXO Ubiquitination and Degradation
- (2009) Wei Fu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Nutrient-dependent mTORC1 Association with the ULK1–Atg13–FIP200 Complex Required for Autophagy
- (2009) Nao Hosokawa et al. MOLECULAR BIOLOGY OF THE CELL
- Cytoplasmic functions of the tumour suppressor p53
- (2009) Douglas R. Green et al. NATURE
- A Gene Network Regulating Lysosomal Biogenesis and Function
- (2009) Marco Sardiello et al. SCIENCE
- Lysosomal disorders: From storage to cellular damage
- (2008) Andrea Ballabio et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- p53 Target Genes Sestrin1 and Sestrin2 Connect Genotoxic Stress and mTOR Signaling
- (2008) Andrei V. Budanov et al. CELL
- SIRT1 Modulation of the Acetylation Status, Cytosolic Localization, and Activity of LKB1
- (2008) Fan Lan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Autophagy fights disease through cellular self-digestion
- (2008) Noboru Mizushima et al. NATURE
- Targeting bile-acid signalling for metabolic diseases
- (2008) Charles Thomas et al. NATURE REVIEWS DRUG DISCOVERY
- E2F1 regulates autophagy and the transcription of autophagy genes
- (2008) S Polager et al. ONCOGENE
- A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy
- (2008) I. H. Lee et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Antagonism of E2F-1 regulated Bnip3 transcription by NF- B is essential for basal cell survival
- (2008) J. Shaw et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now