Mechanosensitive calcium flashes promote sustained RhoA activation during tight junction remodeling

Optogenetic control of small GTPases reveals RhoA mediates intracellular calcium signaling

(2021) Hironori Inaba et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Calcium Wave Promotes Cell Extrusion

(2020) Yasuto Takeuchi et al.   CURRENT BIOLOGY

Actin-Membrane Release Initiates Cell Protrusions

(2020) Erik S. Welf et al.   DEVELOPMENTAL CELL

Rho Flares Repair Local Tight Junction Leaks

(2019) Rachel E. Stephenson et al.   DEVELOPMENTAL CELL

Anillin Promotes Cell Contractility by Cyclic Resetting of RhoA Residence Kinetics

(2019) Srikanth Budnar et al.   DEVELOPMENTAL CELL

Alveolar Stretch Activation of Endothelial Piezo1 Protects Adherens Junctions and Lung Vascular Barrier

(2019) Ming Zhong et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Multiscale dynamics of tight junction remodeling

(2019) Saranyaraajan Varadarajan et al.   JOURNAL OF CELL SCIENCE

Piezo2 channel regulates RhoA and actin cytoskeleton to promote cell mechanobiological responses

(2018) Carlos Pardo-Pastor et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell Membranes Resist Flow

(2018) Zheng Shi et al.   CELL

A Mechanosensitive RhoA Pathway that Protects Epithelia against Acute Tensile Stress

(2018) Bipul R. Acharya et al.   DEVELOPMENTAL CELL

Calcium signals drive cell shape changes during zebrafish midbrain–hindbrain boundary formation

(2017) Srishti U. Sahu et al.   MOLECULAR BIOLOGY OF THE CELL

Visualizing the dynamic coupling of claudin strands to the actin cytoskeleton through ZO-1

(2017) Christina M. Van Itallie et al.   MOLECULAR BIOLOGY OF THE CELL

Stretched divisions

(2017) Carl-Philipp Heisenberg   NATURE

Mechanical stretch triggers rapid epithelial cell division through Piezo1

(2017) S. A. Gudipaty et al.   NATURE

Epithelial cell extrusion: Pathways and pathologies

(2017) Swapna Aravind Gudipaty et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

How cells channel their stress: Interplay between Piezo1 and the cytoskeleton

(2017) Jamison L. Nourse et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Optogenetic control of RhoA reveals zyxin-mediated elasticity of stress fibres

(2017) Patrick W. Oakes et al.   Nature Communications

Calcium spikes, waves and oscillations in a large, patterned epithelial tissue

(2017) Ramya Balaji et al.   Scientific Reports

Maintenance of the Epithelial Barrier and Remodeling of Cell-Cell Junctions during Cytokinesis

(2016) Tomohito Higashi et al.   CURRENT BIOLOGY

Inflammation and the Intestinal Barrier: Leukocyte–Epithelial Cell Interactions, Cell Junction Remodeling, and Mucosal Repair

(2016) Anny-Claude Luissint et al.   GASTROENTEROLOGY

Local RhoA activation induces cytokinetic furrows independent of spindle position and cell cycle stage

(2016) Elizabeth Wagner et al.   JOURNAL OF CELL BIOLOGY

Membrane dynamics during cellular wound repair

(2016) Nicholas R. Davenport et al.   MOLECULAR BIOLOGY OF THE CELL

Tight junctions: from simple barriers to multifunctional molecular gates

(2016) Ceniz Zihni et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Forcing open TRP channels: Mechanical gating as a unifying activation mechanism

(2015) Chao Liu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mechanistic Insights into the Anchorage of the Contractile Ring by Anillin and Mid1

(2015) Lingfei Sun et al.   DEVELOPMENTAL CELL

Mechanical stimulation induces formin-dependent assembly of a perinuclear actin rim

(2015) Xiaowei Shao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell-Autonomous Ca 2+ Flashes Elicit Pulsed Contractions of an Apical Actin Network to Drive Apical Constriction during Neural Tube Closure

(2015) Neophytos Christodoulou et al.   Cell Reports

Ca2+Signaling in Cytoskeletal Reorganization, Cell Migration, and Cancer Metastasis

(2015) Feng-Chiao Tsai et al.   Biomed Research International

Ethanol disrupts intestinal epithelial tight junction integrity through intracellular calcium-mediated Rho/ROCK activation

(2014) Elhaseen Elamin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Anillin Regulates Cell-Cell Junction Integrity by Organizing Junctional Accumulation of Rho-GTP and Actomyosin

(2014) Ciara C. Reyes et al.   CURRENT BIOLOGY

Functional Role for Piezo1 in Stretch-evoked Ca2+Influx and ATP Release in Urothelial Cell Cultures

(2014) Tatsuya Miyamoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ion channels contribute to the regulation of cell sheet forces during Drosophila dorsal closure

(2013) G. L. Hunter et al.   DEVELOPMENT

ARP2/3-mediated junction-associated lamellipodia control VE-cadherin–based cell junction dynamics and maintain monolayer integrity

(2013) Abdallah Abu Taha et al.   MOLECULAR BIOLOGY OF THE CELL

Ultrasensitive fluorescent proteins for imaging neuronal activity

(2013) Tsai-Wen Chen et al.   NATURE

Inositol kinase and its product accelerate wound healing by modulating calcium levels, Rho GTPases, and F-actin assembly

(2013) X. Soto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanics of Epithelial Tissue Homeostasis and Morphogenesis

(2013) C. Guillot et al.   SCIENCE

TULIPs: tunable, light-controlled interacting protein tags for cell biology

(2012) Devin Strickland et al.   NATURE METHODS

Activation of TRPV4 Strengthens the Tight-Junction Barrier in Human Epidermal Keratinocytes

(2012) Y. Akazawa et al.   SKIN PHARMACOLOGY AND PHYSIOLOGY

Segregation of PIP2 and PIP3 into distinct nanoscale regions within the plasma membrane

(2012) J. Wang et al.   Biology Open

The Mechanosensitive Ion Channel Piezo1 Is Inhibited by the Peptide GsMTx4

(2011) Chilman Bae et al.   BIOCHEMISTRY

Local, persistent activation of Rho GTPases during plasticity of single dendritic spines

(2011) Hideji Murakoshi et al.   NATURE

Cytoskeletal Regulation of Epithelial Barrier Function During Inflammation

(2010) Andrei I. Ivanov et al.   AMERICAN JOURNAL OF PATHOLOGY

c-Jun NH2-terminal kinase-2 mediates osmotic stress-induced tight junction disruption in the intestinal epithelium

(2010) G. Samak et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Epithelial Barriers in Homeostasis and Disease

(2010) Amanda M. Marchiando et al.   Annual Review of Pathology-Mechanisms of Disease

The TRPV4 Channel Contributes to Intercellular Junction Formation in Keratinocytes

(2010) Takaaki Sokabe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MLCK-dependent exchange and actin binding region-dependent anchoring of ZO-1 regulate tight junction barrier function

(2010) D. Yu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels

(2010) B. Coste et al.   SCIENCE

Integration of Single and Multicellular Wound Responses

(2009) Andrew G. Clark et al.   CURRENT BIOLOGY

The TRPV4 Cation Channel Mediates Stretch-evoked Ca2+Influx and ATP Release in Primary Urothelial Cell Cultures

(2009) Tsutomu Mochizuki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Calcium flickers steer cell migration

(2009) Chaoliang Wei et al.   NATURE

Role of cortical tension in bleb growth

(2009) J.-Y. Tinevez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Frequency and peak stretch magnitude affect alveolar epithelial permeability

(2008) T. S. Cohen et al.   EUROPEAN RESPIRATORY JOURNAL

A short history of blebbing

(2008) G.T. CHARRAS   JOURNAL OF MICROSCOPY

Regulation of cytokinesis by Rho GTPase flux

(2008) Ann L. Miller et al.   NATURE CELL BIOLOGY

Calcium waves

(2008) L. F Jaffe   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES