标题
Tight junctions: from simple barriers to multifunctional molecular gates
作者
关键词
-
出版物
NATURE REVIEWS MOLECULAR CELL BIOLOGY
Volume 17, Issue 9, Pages 564-580
出版商
Springer Nature
发表日期
2016-06-30
DOI
10.1038/nrm.2016.80
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Beyond Ussing's chambers: contemporary thoughts on integration of transepithelial transport
- (2016) Jeremy R. Herrmann et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Occludin deficiency promotes ethanol-induced disruption of colonic epithelial junctions, gut barrier dysfunction and liver damage in mice
- (2016) Hina Mir et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- ZO-2 silencing induces renal hypertrophy through a cell cycle mechanism and the activation of YAP and the mTOR pathway
- (2016) Alaide Domínguez-Calderón et al. MOLECULAR BIOLOGY OF THE CELL
- Bradykinin increased the permeability of BTB via NOS/NO/ZONAB-mediating down-regulation of claudin-5 and occludin
- (2015) Li-bo Liu et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- PARD3 induces TAZ activation and cell growth by promoting LATS1 and PP1 interaction
- (2015) X.-B. Lv et al. EMBO REPORTS
- ZO-1 controls endothelial adherens junctions, cell–cell tension, angiogenesis, and barrier formation
- (2015) Olga Tornavaca et al. JOURNAL OF CELL BIOLOGY
- Model for the Architecture of Claudin-Based Paracellular Ion Channels through Tight Junctions
- (2015) Hiroshi Suzuki et al. JOURNAL OF MOLECULAR BIOLOGY
- A non-tight junction function of claudin-7—Interaction with integrin signaling in suppressing lung cancer cell proliferation and detachment
- (2015) Zhe Lu et al. Molecular Cancer
- Assembly and function of claudins: Structure–function relationships based on homology models and crystal structures
- (2015) G. Krause et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Transmembrane proteins of the tight junctions at the blood–brain barrier: Structural and functional aspects
- (2015) Reiner F. Haseloff et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Conceptual barriers to understanding physical barriers
- (2015) Amulya Lingaraju et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Claudin-2-dependent paracellular channels are dynamically gated
- (2015) Christopher R Weber et al. eLife
- Proteomic Analysis of Proteins Surrounding Occludin and Claudin-4 Reveals Their Proximity to Signaling and Trafficking Networks
- (2015) Karin Fredriksson et al. PLoS One
- Nuclear distribution of claudin-2 increases cell proliferation in human lung adenocarcinoma cells
- (2014) Akira Ikari et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Tight junction dynamics: the role of junctional adhesion molecules (JAMs)
- (2014) S. Garrido-Urbani et al. CELL AND TISSUE RESEARCH
- ZO Proteins Redundantly Regulate the Transcription Factor DbpA/ZONAB
- (2014) Domenica Spadaro et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The association of microtubules with tight junctions is promoted by cingulin phosphorylation by AMPK
- (2014) Tomoki Yano et al. JOURNAL OF CELL BIOLOGY
- MarvelD3 couples tight junctions to the MEKK1–JNK pathway to regulate cell behavior and survival
- (2014) Emily Steed et al. JOURNAL OF CELL BIOLOGY
- CFTR interacts with ZO-1 to regulate tight junction assembly and epithelial differentiation through the ZONAB pathway
- (2014) Ye Chun Ruan et al. JOURNAL OF CELL SCIENCE
- GEF-H1 controls focal adhesion signaling that regulates mesenchymal stem cell lineage commitment
- (2014) I.-H. Huang et al. JOURNAL OF CELL SCIENCE
- Signalling at tight junctions during epithelial differentiation and microbial pathogenesis
- (2014) C. Zihni et al. JOURNAL OF CELL SCIENCE
- Tricellulin regulates junctional tension of epithelial cells at tricellular contacts through Cdc42
- (2014) Y. Oda et al. JOURNAL OF CELL SCIENCE
- Claudins and the Kidney
- (2014) A. S. L. Yu JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Trans-dimerization of JAM-A regulates Rap2 and is mediated by a domain that is distinct from the cis-dimerization interface
- (2014) Ana C. Monteiro et al. MOLECULAR BIOLOGY OF THE CELL
- ZO-1 Knockout by TALEN-Mediated Gene Targeting in MDCK Cells: Involvement of ZO-1 in the Regulation of Cytoskeleton and Cell Shape
- (2014) Shinsaku Tokuda et al. PLoS One
- Crystal Structure of a Claudin Provides Insight into the Architecture of Tight Junctions
- (2014) H. Suzuki et al. SCIENCE
- Tight junctions and the regulation of gene expression
- (2014) Lorenza González-Mariscal et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- RhoGTPases, actomyosin signaling and regulation of the Epithelial Apical Junctional Complex
- (2014) Miguel Quiros et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Molecular organization and function of invertebrate occluding junctions
- (2014) Yasushi Izumi et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- The emergence of the concept of tight junctions and physiological regulation by ouabain
- (2014) I. Larre et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Tight junction, selective permeability, and related diseases
- (2014) Susanne M. Krug et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Architecture of tight junctions and principles of molecular composition
- (2014) Christina M. Van Itallie et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- JAM-related proteins in mucosal homeostasis and inflammation
- (2014) Anny-Claude Luissint et al. Seminars in Immunopathology
- Dbl3 drives Cdc42 signaling at the apical margin to regulate junction position and apical differentiation
- (2013) Ceniz Zihni et al. JOURNAL OF CELL BIOLOGY
- ZO-1 recruitment to -catenin - a novel mechanism for coupling the assembly of tight junctions to adherens junctions
- (2013) J. L. Maiers et al. JOURNAL OF CELL SCIENCE
- Epithelial barrier assembly requires coordinated activity of multiple domains of the tight junction protein ZO-1
- (2013) L. S. Rodgers et al. JOURNAL OF CELL SCIENCE
- Tetraspanin CD9 links junctional adhesion molecule-A to αvβ3 integrin to mediate basic fibroblast growth factor–specific angiogenic signaling
- (2013) Swetha S. D. Peddibhotla et al. MOLECULAR BIOLOGY OF THE CELL
- Claudins and the Modulation of Tight Junction Permeability
- (2013) Dorothee Günzel et al. PHYSIOLOGICAL REVIEWS
- Cingulin, paracingulin, and PLEKHA7: signaling and cytoskeletal adaptors at the apical junctional complex
- (2012) Sandra Citi et al. Annals of the New York Academy of Sciences
- Claudin-17 forms tight junction channels with distinct anion selectivity
- (2012) Susanne M. Krug et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Apicobasal polarity in the kidney
- (2012) Marc A. Schlüter et al. EXPERIMENTAL CELL RESEARCH
- Loss of Claudins 2 and 15 From Mice Causes Defects in Paracellular Na+ Flow and Nutrient Transport in Gut and Leads to Death from Malnutrition
- (2012) Masami Wada et al. GASTROENTEROLOGY
- Lipid Polarity Is Maintained in Absence of Tight Junctions
- (2012) Junichi Ikenouchi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Epithelial junction formation requires confinement of Cdc42 activity by a novel SH3BP1 complex
- (2012) Ahmed Elbediwy et al. JOURNAL OF CELL BIOLOGY
- Analysis of the 'angulin' proteins LSR, ILDR1 and ILDR2 - tricellulin recruitment, epithelial barrier function and implication in deafness pathogenesis
- (2012) T. Higashi et al. JOURNAL OF CELL SCIENCE
- Cingulin is dispensable for epithelial barrier function and tight junction structure, and plays a role in the control of claudin-2 expression and response to duodenal mucosa injury
- (2012) L. Guillemot et al. JOURNAL OF CELL SCIENCE
- In tight junctions, claudins regulate the interactions between occludin, tricellulin and marvelD3, which, inversely, modulate claudin oligomerization
- (2012) J. Cording et al. JOURNAL OF CELL SCIENCE
- Stress- and Rho-activated ZO-1-associated nucleic acid binding protein binding to p21 mRNA mediates stabilization, translation, and cell survival
- (2012) M. Nie et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Rho GTP exchange factor ARHGEF11 regulates the integrity of epithelial junctions by connecting ZO-1 and RhoA-Myosin II signaling
- (2012) M. Itoh et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cell polarity proteins and cancer
- (2012) Saskia I.J. Ellenbroek et al. SEMINARS IN CANCER BIOLOGY
- A Tight Junction-Associated Merlin-Angiomotin Complex Mediates Merlin's Regulation of Mitogenic Signaling and Tumor Suppressive Functions
- (2011) Chunling Yi et al. CANCER CELL
- Angiomotin is a novel Hippo pathway component that inhibits YAP oncoprotein
- (2011) B. Zhao et al. GENES & DEVELOPMENT
- LSR defines cell corners for tricellular tight junction formation in epithelial cells
- (2011) S. Masuda et al. JOURNAL OF CELL SCIENCE
- Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation
- (2011) Jean-Cheng Kuo et al. NATURE CELL BIOLOGY
- Spatially restricted activation of RhoA signalling at epithelial junctions by p114RhoGEF drives junction formation and morphogenesis
- (2011) Stephen J. Terry et al. NATURE CELL BIOLOGY
- The Rho GEFs LARG and GEF-H1 regulate the mechanical response to force on integrins
- (2011) Christophe Guilluy et al. NATURE CELL BIOLOGY
- Bves Modulates Tight Junction Associated Signaling
- (2011) Patricia K. Russ et al. PLoS One
- Functional complexes between YAP2 and ZO-2 are PDZ domain-dependent, and regulate YAP2 nuclear localization and signalling
- (2010) Tsutomu Oka et al. BIOCHEMICAL JOURNAL
- aPKC Phosphorylation of Bazooka Defines the Apical/Lateral Border in Drosophila Epithelial Cells
- (2010) Eurico Morais-de-Sá et al. CELL
- Crumbs/DaPKC-Dependent Apical Exclusion of Bazooka Promotes Photoreceptor Polarity Remodeling
- (2010) Rhian F. Walther et al. CURRENT BIOLOGY
- The Merlin/NF2 Tumor Suppressor Functions through the YAP Oncoprotein to Regulate Tissue Homeostasis in Mammals
- (2010) Nailing Zhang et al. DEVELOPMENTAL CELL
- Loss of Claudin-15, but Not Claudin-2, Causes Na+ Deficiency and Glucose Malabsorption in Mouse Small Intestine
- (2010) Atsushi Tamura et al. GASTROENTEROLOGY
- The Drosophila Claudin Kune-kune Is Required for Septate Junction Organization and Tracheal Tube Size Control
- (2010) K. S. Nelson et al. GENETICS
- Insights into Regulated Ligand Binding Sites from the Structure of ZO-1 Src Homology 3-Guanylate Kinase Module
- (2010) Ming F. Lye et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Symplekin promotes tumorigenicity by up-regulating claudin-2 expression
- (2010) M. Buchert et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Dynamics and functions of tight junctions
- (2010) Emily Steed et al. TRENDS IN CELL BIOLOGY
- The Y-box factor ZONAB/DbpA associates with GEF-H1/Lfc and mediates Rho-stimulated transcription
- (2009) Mei Nie et al. EMBO REPORTS
- Structure-Function Studies of Claudin Extracellular Domains by Cysteine-scanning Mutagenesis
- (2009) Susanne Angelow et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- JAM-A promotes neutrophil chemotaxis by controlling integrin internalization and recycling
- (2009) M. R. Cera et al. JOURNAL OF CELL SCIENCE
- Claudin-10 exists in six alternatively spliced isoforms that exhibit distinct localization and function
- (2009) D. Gunzel et al. JOURNAL OF CELL SCIENCE
- Similar and Distinct Properties of MUPP1 and Patj, Two Homologous PDZ Domain-Containing Tight-Junction Proteins
- (2009) M. Adachi et al. MOLECULAR AND CELLULAR BIOLOGY
- Junctional Adhesion Molecule A Interacts with Afadin and PDZ-GEF2 to Activate Rap1A, Regulate β1 Integrin Levels, and Enhance Cell Migration
- (2009) Eric A. Severson et al. MOLECULAR BIOLOGY OF THE CELL
- The C. elegans Zonula Occludens Ortholog Cooperates with the Cadherin Complex to Recruit Actin during Morphogenesis
- (2008) Christina Lockwood et al. CURRENT BIOLOGY
- Tjp3/zo-3 is critical for epidermal barrier function in zebrafish embryos
- (2008) Tanja K. Kiener et al. DEVELOPMENTAL BIOLOGY
- Regulation of epithelial and endothelial junctions by PAR proteins
- (2008) Klaus Ebnet Frontiers in Bioscience-Landmark
- The tight junction protein complex undergoes rapid and continuous molecular remodeling at steady state
- (2008) Le Shen et al. JOURNAL OF CELL BIOLOGY
- Molecular Basis for Cation Selectivity in Claudin-2–based Paracellular Pores: Identification of an Electrostatic Interaction Site
- (2008) Alan S.L. Yu et al. JOURNAL OF GENERAL PHYSIOLOGY
- Early Embryonic Lethality of Mice Lacking ZO-2, but Not ZO-3, Reveals Critical and Nonredundant Roles for Individual Zonula Occludens Proteins in Mammalian Development
- (2008) J. Xu et al. MOLECULAR AND CELLULAR BIOLOGY
- Deficiency of Zonula Occludens-1 Causes Embryonic Lethal Phenotype Associated with Defected Yolk Sac Angiogenesis and Apoptosis of Embryonic Cells
- (2008) Tatsuya Katsuno et al. MOLECULAR BIOLOGY OF THE CELL
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